Increased endothelial cell-cell junction size on stiff matrices is diminished after simvastatin treatment. by Marsha C. Lampi (845609)

“…<p>Endothelial monolayers are stained for VE-cadherin and cell-cell junction sizes are measured with control and 1 μM simvastatin treatments. (A) Representative images of fluorescently stained VE-cadherin monolayers indicating where junction width measurements were made (black line). …”

Simvastatin reduces vinculin localization at cell-cell adhesions in endothelial monolayers. by Marsha C. Lampi (845609)

“…(C) Vinculin localization per monolayer at cell-cell adhesions, a readout of intercellular junction tension, is quantified and increases with matrix stiffness but is significantly decreased with the statin treatment at higher matrix stiffnesses (n = 3, 70–90 fields of view per condition). …”

Biofilm formation assays. by Zezhang T. Wen (135862)

“…The results demonstrate that PBP1a-deficiency significantly decreased biofilm formation by the deficient mutant (* indicates differences at <i>P</i><0.001 when compared to the wild-type, UA159 under the same conditions). …”

Figure S1 - Effects of Negative Pressure Wound Therapy on Mesenchymal Stem Cells Proliferation and Osteogenic Differentiation in a Fibrin Matrix by Jin Zhu (164147)

Simvastatin alters actin organization, cell morphology, and Rac1 activity in endothelial monolayers. by Marsha C. Lampi (845609)

“…Cell circularity, where a perfectly circular cell has a value of 1, decreases with increasing simvastatin concentration (n = 3, 50–54 cells per condition). …”

Canonical and Noncanonical Sites Determine NPT2A Binding Selectivity to NHERF1 PDZ1 by Tatyana Mamonova (753968)

“…Experimentally introduced mutation in PDZ1 (Glu43Asp and His27Asn) decreased binding to NPT2A. Conversely, introduction of Asp183Glu and Asn167His mutations in PDZ2 promoted the formation of favorable interactions yielding micromolar <i>K</i>_Ds. …”

Ten years of improving glycemic control in pediatric diabetes care: Data from the Norwegian Childhood Diabetes Registry by Heiko Bratke (10112600)

“…The predictor variables in the adjusted linear mixed-effects model were (1) the use of diabetes technology, (2) the use of carbohydrate counting for meal bolusing, and (3) whether the patient’s diabetes team participated in a quality improvement project.</p><p dir="ltr">Results: Mean HbA1c decreased from 8.2% (2013) to 7.2% (2021), and the proportion of youth reaching an HbA1c <7.0% increased from 13% (2013) to 43% (2022). …”

Tomato HsfA1a plays a critical role in plant drought tolerance by activating <i>ATG</i> genes and inducing autophagy by Yu Wang (12152)

“…On the other hand, <i>HsfA1a</i>-silenced plants increased while its overexpression decreased the levels of insoluble proteins which were highly ubiquitinated under drought stress. …”

Obesity prevalence of NYC public school K-8 students by race/ethnicity and home-neighborhood poverty level, 2019–20. by Kira L. Argenio (18563302)

Voltage in the steady state of the membrane system as a function of higher concentration for configurations A (black) and B (red). by Sławomir Grzegorczyn (12035398)

Mechanistic Investigation of the Hydrogenation of Ketones Catalyzed by a Ruthenium(II) Complex Featuring an N-Heterocyclic Carbene with a Tethered Primary Amine Donor: Evidence for... by Wylie W. N. O (1755865)

“…The transfer to the ketone of a hydride and proton equivalent that are produced in the heterolytic splitting reaction yields the product in a fast, low activation barrier step. …”

Mechanistic Investigation of the Hydrogenation of Ketones Catalyzed by a Ruthenium(II) Complex Featuring an N-Heterocyclic Carbene with a Tethered Primary Amine Donor: Evidence for... by Wylie W. N. O (1755865)

“…The transfer to the ketone of a hydride and proton equivalent that are produced in the heterolytic splitting reaction yields the product in a fast, low activation barrier step. …”

Mechanistic Investigation of the Hydrogenation of Ketones Catalyzed by a Ruthenium(II) Complex Featuring an N-Heterocyclic Carbene with a Tethered Primary Amine Donor: Evidence for... by Wylie W. N. O (1755865)

“…The transfer to the ketone of a hydride and proton equivalent that are produced in the heterolytic splitting reaction yields the product in a fast, low activation barrier step. …”

Theoretical Studies on the Mechanism, Enantioselectivity, and Axial Ligand Effect of a Ru(salen)-Catalyzed Asymmetric Cyclopropanation Reaction by Ting Shi (3955)

“…Five proposed reaction pathways, including (1) a stepwise process containing the formation of carbene species and cyclopropanation step (path a), (2) a one-step process (path b), (3) a bis-carbene mechanism (path c), (4) a three-centered-intermediate pathway (path d), and (5) the main side reaction of dimerization of EDA (path e), are taken into consideration to determine the most favorable mechanism. …”

Proteolysis of CtrA is essential in <i>S</i>. <i>meliloti</i> and requires at least CpdR, RcdA and the last three amino acids of CtrA. by Francesco Pini (739798)

“…Pulse-chase experiment of showing decrease over time of radiolabeled CtrA in <i>S</i>. …”

Epigenome modulated xenobiotic detoxification pathways control DMBA-induced breast cancer in agouti A^vy/a mice by Simbarashe Mazambani (6683576)

“…Compared to pseudoagouti littermates, a significant decrease in tumour latency with increased tumour burden was observed in slightly mottled and yellow littermates (<i>p</i> ≤ 0.05). …”

Data_Sheet_1_Alanine Scanning Mutagenesis of the C-Terminal Cytosolic End of Gpm6a Identifies Key Residues Essential for the Formation of Filopodia.pdf by Nicolás M. Rosas (5712830)

“…Expression levels of both truncation mutants were not affected but we observed decrease in the amount of both truncated proteins on cell surface suggesting that the incapacity of the Gpm6a lacking C-terminus to induce filopodium formation is not due to the lower amount of Gpm6a on cell surface. …”

Ectopic expression of miR-181a enhances lymphoid differentiation in the <i>ETV6/RUNX1</i>-positive cell line and primary ALL blasts. by Yung-Li Yang (514952)

“…In the comparison with the infection control (NC), 181A1-LV-transduced cells derived from patient #1 and #2 both showed a decrease in CD10^High cells (Patient #1: NC 10.1% / MFI 40.92, 181A1 6.95% / MFI 39.51; Patient #2: NC 40.1% / MFI 424.28, 181A1 29.5% / MFI 444.24) and a relative increase in CD10^Low cells (Patient #1: NC 87.98% / MFI 165.49, 181A1 91.05% / MFI 156.68; Patient #2: NC 58.1% / MFI 1929.88, 181A1 69% / 1854.4). …”

DataSheet_1_The extremely small body size of Williamson’s mouse deer (Tragulus williamsoni) allows coexistence with sympatric larger ungulates through temporal avoidance.zip by Ru-Chuan He (17098336)

“…We hypothesized that: 1) because of its extremely small body size, competition with the larger ungulates would be relatively weak, allowing spatial co-existence but still requiring temporal avoidance, and 2) the strength of avoidance would increases with decreasing differences in body size. …”

Albumin Abundance and Its Glycation Status Determine Hemoglobin Glycation by Mashanipalya G. Jagadeeshaprasad (5843024)

“…Diabetes diagnosis and management majorly depend upon the measurement of glycated hemoglobin (HbA1c) levels. Various factors influence HbA1c levels such as the use of various analytical methods and the presence of various clinical conditions. …”