Supplementary Material for: Poly-(ADP-Ribose) Polymerase-1 Promotes Prothrombin Gene Transcription and Produces Des-Gamma-Carboxy Prothrombin in Hepatocellular Carcinoma by Taniguchi T. (3908848)

“…A SEAP vector with -2985 to +27 showed a very high transcription activity in DCP-producing Huh-1 cells. However, transcription abruptly decreased when the vector with -2955 to +27 was transfected, and then remained at the similar levels with larger deletion mutants, indicating the existence of a cis-element at -2985 to -2955 (31-bp). …”

A Framework for Time-Driven Activity-Based Costing for Orthopedic Procedure by Holozada, Bayan Hani

“…This study used method of Time-Driven Activity-Based costing (TDABC) approach to examined cost reduction in healthcare sector, Knee Arthroplasty Department in Al-Emadi Hospital as case-study for delivering a primary knee arthroplasty consultation. The purpose of the study is to propose an optimization model that tends to determine significant and insignificant resources and cost uncertainties in a particular healthcare service. …”
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Immunofluorescence staining patterns for 5-mC and 5-hmC in CIN3 lesions with overlying columnar epithelium, showing extensive heterogeneity for methylation and hydroxymethylation. by Jobran M. Moshi (18405149)

A Risk-Based Framework for Assessing the Effectiveness of Stratospheric Aerosol Geoengineering by Angus J. Ferraro (522417)

“…We present a simple, intuitive risk-based framework for classifying these impacts according to whether geoengineering increases or decreases the risk of substantial climate change, with further classification by the level of existing risk from climate change from increasing carbon dioxide concentrations. …”

Application research and progress of microalgae as a novel protein resource in the future by S. L. Ma (22409308)

“…Microalgae have emerged as a promising alternative, with higher protein content, better nutritional quality, and greater environmental resilience compared to conventional crops. …”

Data_Sheet_1_Simultaneous detection of infectious bronchitis virus and avian metapneumovirus genotypes A, B, and C by multiplex RT-qPCR assay in chicken tracheal samples in Ecuador... by Anthony Loor-Giler (19170247)

“…Particularly, aMPV has three genotypes that have been reported with greater frequency in chickens: aMPV-A, aMPV-B, and aMPV-C. …”

Anti-Angiogenic and Anti-Inflammatory Properties of Kahweol, a Coffee Diterpene by Casimiro Cárdenas (210714)

“…<div><h3>Background</h3><p>Epidemiological studies have shown that unfiltered coffee consumption is associated with a low incidence of cancer. This study aims to identify the effects of kahweol, an antioxidant diterpene contained in unfiltered coffee, on angiogenesis and key inflammatory molecules.…”

Reduced FS excitability promotes a paradoxical response to inhibitory stimulation. by Alexander Bryson (11570876)

“…<p><b>A)</b> The presence of an ISN was explored by applying an external current stimulus to the FS (y axis) and NFS (x axis) population and recording the mean change in inhibitory (hyperpolarising) current received by the PC population (increased inhibitory current in green, decreased inhibitory current in red). …”

DataSheet1_The Dictyostelium Model for Mucolipidosis Type IV.PDF by Claire Y. Allan (12409690)

“…Both increasing and decreasing mucolipin expression caused the formation of smaller slugs and larger numbers of fruiting bodies during multicellular development, suggesting that mucolipin is involved in initiation of aggregation centers. …”

Graphical representation of the proportion of linkage explained by the SNP in Campora (A) and Cardile (B). by Daniela Ruggiero (140756)

“…A greater effect is observed when the three SNPs detected in Campora are considered simultaneously.…”

Spaceflight in microgravity reduces sGAG content in the femoral head and distal epiphysis. by Rukmani Cahill (20939813)

INCREASE IN WATER-SCARCITY RISK IN A BRAZILIAN DRY-REGION RESERVOIR by MARGARITA MARIA LÓPEZ GIL (10482261)

“…<div><p>ABSTRACT This study assesses the extent to which silting increases water-scarcity risk, considering the temporal reduction of water availability and increased demand using land use and water-demand scenarios at the transition of Caatinga and Cerrado biomes of the Bocaina reservoir watershed (103hm4), in the Brazilian dry region. Methodological steps were: reservoir silting measured in-situ 20 years after dam construction; climate variables computed with the aid of a conventional station (2005-2014); soil erodibility assessed using 16 soil samples; and topography and land cover estimated based on 21 years of Landsat imagery. …”

Aβ has no effect on NMDA-receptor mediated ion conductance. by Albert Tamburri (418150)

“…Following the sharp decrease in the EPSC amplitude, Aβ oligomers were applied (arrow on the right). …”

Building a mechanistic mathematical model of hepatitis C virus entry by Mphatso Kalemera (6476033)

“…<div><p>The mechanism by which hepatitis C virus (HCV) gains entry into cells is a complex one, involving a broad range of host proteins. …”

Loss of PRC2 activity leads to changes in DNA methylation. a, by James A. Hagarman (104059)

“…Methylated CpGs are indicated by filled-in circles. <b>c,</b> A Fisher’s exact test was conducted for each CpG in (b) (** p<.01, *** p<.001). …”

Enrichment of a Type I Interferon Gene Set in SUS Pigs. by Jamie M. Wilkinson (798436)

“…The score is calculated by walking down a list of genes ranked by their correlation with the LBW phenotype, increasing a running-sum statistic when a gene in that gene set is encountered (each black vertical line underneath the enrichment plot) and decreasing it when a gene that isn’t in the gene set is encountered. …”

Alcohol consumption during pregnancy and perinatal results: a cohort study by Mariana Sbrana (10445498)

“…<div><p>ABSTRACT CONTEXT AND OBJECTIVE: Alcohol consumption during pregnancy is a significant social problem that may be associated with adverse perinatal outcomes. …”

DPP6 regulates a channel with properties similar to TASK-3. by Brian M. Nadin (401054)

“…Current clamp recordings from cells before and after application of pH 6.0 external solution show changes in the voltage responses to a series of 10 pA current steps. For these studies we only characterized changes in input conductance because pH 6.0 partially blocks voltage gated channels Na⁺ channels, making an analysis of effects of low pH on firing threshold complex and essentially uninformative for our purposes <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0060831#pone.0060831-Hille1" target="_blank">[73]</a>. …”

Image_1_Spectrum Degradation of Hippocampal LFP During Euthanasia.JPEG by Yuchen Zhou (1601536)

“…As the collapse of activity occurred later in hippocampus compared with medial entorhinal cortex, it suggests that the ability of a neural network to maintain the 1/f slope with decreasing energy is a function of general connectivity. …”

Internal loading potential of phosphorus in reservoirs along a semiarid watershed by Diana Souza Moura (8743428)

“…Reservoirs R#5, R#1 and R#2 showed a tendency of decreasing total phosphorus (PT) as the sediment depth increased, probably indicating an increase of allochthonous phosphorus loading along time. …”