DataSheet2_Real-World Data and Budget Impact Analysis (BIA): Evaluation of a Targeted Next-Generation Sequencing Diagnostic Approach in Two Orthopedic Rare Diseases.PDF by Elena Pedrini (224672)

“…</p><p>Conclusions: Our targeted NGS diagnostic approach decreases time to diagnosis and costs, appearing to be beneficial and recommended both for patients and from a healthcare perspective in routine diagnosis also considering very small gene panels and a low patient flow. …”

DataSheet1_Real-World Data and Budget Impact Analysis (BIA): Evaluation of a Targeted Next-Generation Sequencing Diagnostic Approach in Two Orthopedic Rare Diseases.PDF by Elena Pedrini (224672)

“…</p><p>Conclusions: Our targeted NGS diagnostic approach decreases time to diagnosis and costs, appearing to be beneficial and recommended both for patients and from a healthcare perspective in routine diagnosis also considering very small gene panels and a low patient flow. …”

DataSheet3_Real-World Data and Budget Impact Analysis (BIA): Evaluation of a Targeted Next-Generation Sequencing Diagnostic Approach in Two Orthopedic Rare Diseases.PDF by Elena Pedrini (224672)

“…</p><p>Conclusions: Our targeted NGS diagnostic approach decreases time to diagnosis and costs, appearing to be beneficial and recommended both for patients and from a healthcare perspective in routine diagnosis also considering very small gene panels and a low patient flow. …”

Data_Sheet_1_Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching.pdf by Anne Marchalot (8814242)

“…Supporting a global effect on CSR, we also observed that the targeting of Iμ dss reduced CSR to IgG3 and, to a lesser extent, IgG2b isotypes. …”

Data_Sheet_1_Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching.pdf by Anne Marchalot (8814242)

“…Supporting a global effect on CSR, we also observed that the targeting of Iμ dss reduced CSR to IgG3 and, to a lesser extent, IgG2b isotypes. …”

Data_Sheet_2_Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching.docx by Anne Marchalot (8814242)

“…Supporting a global effect on CSR, we also observed that the targeting of Iμ dss reduced CSR to IgG3 and, to a lesser extent, IgG2b isotypes. …”

Data_Sheet_2_Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching.docx by Anne Marchalot (8814242)

“…Supporting a global effect on CSR, we also observed that the targeting of Iμ dss reduced CSR to IgG3 and, to a lesser extent, IgG2b isotypes. …”

Table 1_Acute whole-body vibration as a recovery strategy did not alter the content of gluteus medius monocarboxylate-transporters, lactatemia, and acidosis induced by intense exer... by Júlia Ribeiro Garcia Carvalho (3390047)

“…The WBV group (WBVG) followed a stepwise recovery protocol on VP, with each step lasting 2 min and the frequencies decreasing in a specific order: 76, 66, 55, 46, and 32 Hz. …”

Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd... by Bo Peng (273834)

Data Sheet 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.pdf by Peerapon Kiatkittikul (22801874)

“…</p>Results<p>[¹⁸F]SMBT-1 was successfully synthesized via nucleophilic substitution of a tosylate precursor, followed by a deprotection step. …”

Table_1_Dietary changes among pregnant individuals compared to pre-pandemic: A cross-sectional analysis of the Pregnancy during the COVID-19 Pandemic (PdP) study.DOCX by Elnaz Vaghef-Mehrabani (14200028)

“…Changes in consumption of the food categories had a curvilinear association with mental health symptoms (except resilience) indicating greater symptoms with either decreased or increased intakes. …”

Inhibition of NM-2 activity through acute blebbistatin treatment slows the kinetics of exocytosis and endocytosis. by Juan A. Flores (587973)

“…<p>Representative traces of capacitance steps from a control (A) and blebbistatin-treated cell (B). …”

Inhibition of NM-2 activity through acute blebbistatin treatment slows the kinetics of exocytosis and endocytosis. by Juan A. Flores (587973)

“…<p>Representative traces of capacitance steps from a control (A) and blebbistatin-treated cell (B). …”

Table_1_Impacts of glacial and sea-ice meltwater, primary production, and ocean CO2 uptake on ocean acidification state of waters by the 79 North Glacier and northeast Greenland sh... by Agneta Fransson (471604)

“…The lowest aragonite saturation state (Ω_Ar) of 1.13 was found in the SL in 2012. Biological CO₂ drawdown at primary production caused increased Ω_Ar in SL, which compensated for most of the Ω_Ar decrease due to the freshwater dilution of carbonate ions reducing total alkalinity, hence preventing corrosive conditions. …”

Image_1_Impacts of glacial and sea-ice meltwater, primary production, and ocean CO2 uptake on ocean acidification state of waters by the 79 North Glacier and northeast Greenland sh... by Agneta Fransson (471604)

“…The lowest aragonite saturation state (Ω_Ar) of 1.13 was found in the SL in 2012. Biological CO₂ drawdown at primary production caused increased Ω_Ar in SL, which compensated for most of the Ω_Ar decrease due to the freshwater dilution of carbonate ions reducing total alkalinity, hence preventing corrosive conditions. …”

Similarity to target (Carlsberg) vs. similarity to source (Sega_Game_Gear). by José A. Capitán (208517)

“…<p>In this example, our semantic path (red) is comprised by jumps whereas shortest paths (green) involve steps (-fold degenerated). However, a slight efficiency loss can be compensated by a truly coherent path. …”

Table 1_Remimazolam used for sedation during spinal anesthesia puncture provides faster sedation effect and increase recovery rate compared to midazolam: a randomized controlled tr... by Peipei Sun (416208)

“…In China’s high-volume operating rooms, this step is crucial to prevent errors. Spinal anesthesia often induces anxiety, making sedation necessary. …”

Selectivity of the Highly Preorganized Tetradentate Ligand 2,9-Di(pyrid-2-yl)-1,10-phenanthroline for Metal Ions in Aqueous Solution, Including Lanthanide(III) Ions and the Uranyl(... by Ashley N. Carolan (2006530)

“…For Ln­(III) ions larger than Sm­(III), there is a steady rise in log <i>K</i>₁ from La­(III) to Sm­(III), while for Ln­(III) ions smaller than Sm­(III), log <i>K</i>₁ decreases slightly to the smallest Ln­(III) ion, Lu­(III). …”

Loss of function mutations in essential genes cause embryonic lethality in pigs by Martijn F. L. Derks (5348063)

“…The lethal haplotypes have a large effect on carrier-by-carrier matings, decreasing litter sizes by 15.1 to 21.6%. The causal mutations are of different type including two splice-site variants (affecting <i>POLR1B</i> and <i>TADA2A</i> genes), one frameshift (<i>URB1</i>), and one missense (<i>PNKP</i>) variant, resulting in a complete loss-of-function of these essential genes. …”

Video1_The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study.m... by Juhina Das (17808068)

“…Flow-cytometric evidences suggest that NLGP treatment upregulated CD8⁺, IFNγ⁺, granzyme B⁺, CD11c⁺ cells in comparison to 4NQO treated mice with a decrease in Ki67⁺ and CD4⁺FoxP3⁺ cells in NLGP treated cohort. …”