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13221
Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors
Published 2020“…The preliminary mechanistic studies indicated that compounds <b>6</b> and <b>43</b> possibly target the HAdV DNA replication process, while compounds <b>46</b> and <b>47</b> suppress later steps of HAdV life cycle. Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC<sub>50</sub> = 0.27 μM), significantly decreased cytotoxicity (CC<sub>50</sub> = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”
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13222
Understanding and Improving the Kinetics of Bulk Carbonation on Sodium Carbonate
Published 2020“…We find that the kinetics of Na<sub>2</sub>CO<sub>3</sub> bulk carbonation is controlled by the <i>I</i><sub>H</sub><sup>+</sup>/<i>V</i><sub>Na</sub><sup>–</sup> defect pair generation in Na<sub>2</sub>CO<sub>3</sub>; we predict that the kinetics can be enhanced by doping lithium into Na<sub>2</sub>CO<sub>3</sub>, which decreases the defect formation energy by 0.13 eV. This prediction was confirmed by our fixed-bed experiments, which found a 125% increase in the initial CO<sub>2</sub> absorption rate and a 29% increase in CO<sub>2</sub> uptake after 36 min exposure in 0.7 wt % (1.0 at. %) Li-doped Na<sub>2</sub>CO<sub>3</sub> compared with undoped Na<sub>2</sub>CO<sub>3</sub>.…”
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13223
Understanding and Improving the Kinetics of Bulk Carbonation on Sodium Carbonate
Published 2020“…We find that the kinetics of Na<sub>2</sub>CO<sub>3</sub> bulk carbonation is controlled by the <i>I</i><sub>H</sub><sup>+</sup>/<i>V</i><sub>Na</sub><sup>–</sup> defect pair generation in Na<sub>2</sub>CO<sub>3</sub>; we predict that the kinetics can be enhanced by doping lithium into Na<sub>2</sub>CO<sub>3</sub>, which decreases the defect formation energy by 0.13 eV. This prediction was confirmed by our fixed-bed experiments, which found a 125% increase in the initial CO<sub>2</sub> absorption rate and a 29% increase in CO<sub>2</sub> uptake after 36 min exposure in 0.7 wt % (1.0 at. %) Li-doped Na<sub>2</sub>CO<sub>3</sub> compared with undoped Na<sub>2</sub>CO<sub>3</sub>.…”
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13224
Understanding and Improving the Kinetics of Bulk Carbonation on Sodium Carbonate
Published 2020“…We find that the kinetics of Na<sub>2</sub>CO<sub>3</sub> bulk carbonation is controlled by the <i>I</i><sub>H</sub><sup>+</sup>/<i>V</i><sub>Na</sub><sup>–</sup> defect pair generation in Na<sub>2</sub>CO<sub>3</sub>; we predict that the kinetics can be enhanced by doping lithium into Na<sub>2</sub>CO<sub>3</sub>, which decreases the defect formation energy by 0.13 eV. This prediction was confirmed by our fixed-bed experiments, which found a 125% increase in the initial CO<sub>2</sub> absorption rate and a 29% increase in CO<sub>2</sub> uptake after 36 min exposure in 0.7 wt % (1.0 at. %) Li-doped Na<sub>2</sub>CO<sub>3</sub> compared with undoped Na<sub>2</sub>CO<sub>3</sub>.…”
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13225
Understanding and Improving the Kinetics of Bulk Carbonation on Sodium Carbonate
Published 2020“…We find that the kinetics of Na<sub>2</sub>CO<sub>3</sub> bulk carbonation is controlled by the <i>I</i><sub>H</sub><sup>+</sup>/<i>V</i><sub>Na</sub><sup>–</sup> defect pair generation in Na<sub>2</sub>CO<sub>3</sub>; we predict that the kinetics can be enhanced by doping lithium into Na<sub>2</sub>CO<sub>3</sub>, which decreases the defect formation energy by 0.13 eV. This prediction was confirmed by our fixed-bed experiments, which found a 125% increase in the initial CO<sub>2</sub> absorption rate and a 29% increase in CO<sub>2</sub> uptake after 36 min exposure in 0.7 wt % (1.0 at. %) Li-doped Na<sub>2</sub>CO<sub>3</sub> compared with undoped Na<sub>2</sub>CO<sub>3</sub>.…”
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13226
Understanding and Improving the Kinetics of Bulk Carbonation on Sodium Carbonate
Published 2020“…We find that the kinetics of Na<sub>2</sub>CO<sub>3</sub> bulk carbonation is controlled by the <i>I</i><sub>H</sub><sup>+</sup>/<i>V</i><sub>Na</sub><sup>–</sup> defect pair generation in Na<sub>2</sub>CO<sub>3</sub>; we predict that the kinetics can be enhanced by doping lithium into Na<sub>2</sub>CO<sub>3</sub>, which decreases the defect formation energy by 0.13 eV. This prediction was confirmed by our fixed-bed experiments, which found a 125% increase in the initial CO<sub>2</sub> absorption rate and a 29% increase in CO<sub>2</sub> uptake after 36 min exposure in 0.7 wt % (1.0 at. %) Li-doped Na<sub>2</sub>CO<sub>3</sub> compared with undoped Na<sub>2</sub>CO<sub>3</sub>.…”
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13227
Understanding and Improving the Kinetics of Bulk Carbonation on Sodium Carbonate
Published 2020“…We find that the kinetics of Na<sub>2</sub>CO<sub>3</sub> bulk carbonation is controlled by the <i>I</i><sub>H</sub><sup>+</sup>/<i>V</i><sub>Na</sub><sup>–</sup> defect pair generation in Na<sub>2</sub>CO<sub>3</sub>; we predict that the kinetics can be enhanced by doping lithium into Na<sub>2</sub>CO<sub>3</sub>, which decreases the defect formation energy by 0.13 eV. This prediction was confirmed by our fixed-bed experiments, which found a 125% increase in the initial CO<sub>2</sub> absorption rate and a 29% increase in CO<sub>2</sub> uptake after 36 min exposure in 0.7 wt % (1.0 at. %) Li-doped Na<sub>2</sub>CO<sub>3</sub> compared with undoped Na<sub>2</sub>CO<sub>3</sub>.…”
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13228
Involvement of Abscisic Acid in PSII Photodamage and D1 Protein Turnover for Light-Induced Premature Senescence of Rice Flag Leaves
Published 2016“…The <i>psf</i> showed evidently decreased D1 protein amount in the senescent leaves. …”