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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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224541
Quantification of alanine aminotransferase (ALT) and histopathology of liver from C57BL/6 mice infected with <i>Leishmania amazonensis</i> and treated for 60 days with <i>Morinda c...
Published 2016“…<p>Noni group treated at 500mg.kg<sup>-1</sup>.day<sup>-1</sup> and Glucantime group treated at 20mg.kg<sup>-1</sup>.twice a week<sup>-1</sup>. Diffuse inflammatory infiltration (arrows) and periportal infiltration (arrow-heads) in the liver of infected mice. …”
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224542
Gene expression in <i>P</i><sub><i>ENO</i></sub><i>-TLO</i> complemented strains.
Published 2023“…<p>(A) Volcano plots with spots representing genes with 2-fold or more change in gene expression (blue decreased; orange increased) relative to the <i>tlo</i>Δ mutant (FDR q <0.05). …”
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224543
Effects of dapagliflozin on HIF1 in IR-injured kidneys (S (n = 5), sham; S+Dapa (n = 5), sham+dapagliflozin; IR (n = 7); vehicle-treated renal IR mice; IR+Dapa (n = 7), dapaglifloz...
Published 2016“…<p>(A) Representative Western blot: dapagliflozin increased HIF1 expression in IR-injured kidneys. …”
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224544
Robust chain-length specific reductions in some intermediate chain and long chain PE phospholipids in peroxisomal mutant brain.
Published 2025“…<p><b>A.</b> Levels in mol% of PE 33:3 in <i>pex2</i> and <i>pex16</i> mutant brains show significant decreases in <i>pex</i> mutant brains. …”
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224545
RA-induced meiosis-associated gene expression was attenuated by JNK inhibitor treatment.
Published 2018“…The number of (E) STRA8-positive germ cells (red, white arrowheads) in the ovaries was dramatically reduced when SP600125 was present in the culture medium compared with the (A) control group (red, white arrows). (F) The expression of SYCP3 in female germ cells was also dramatically reduced with SP600125 treatment, and meiosis was blocked during early leptotene stage (white arrowheads) compared with the (B) control group (red, white arrows). …”
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224546
Data Sheet 1_Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model.docx
Published 2025“…</p>Methods<p>Build 4T1 breast cancer xenograft tumor model in Balb/c mice, intraperitoneal injection of DOX (5mg/kg) once a week, build the model of DOX induced chemotherapy related cognitive impairment (CRCI), and the administration lasted for three weeks. …”
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224547
Timing of glucocorticoid administration determines severity of lipid metabolism and behavioral effects in rats
Published 2016“…<p>Glucocorticoids (GCs) are a group of steroid hormones secreted by the adrenal glands in circadian cycles, and the dysregulation of GC signaling has been suggested to cause metabolic syndrome. …”
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224548
Image2_Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms.TIF
Published 2022“…<p>Cholestasis is a clinical syndrome triggered by the accumulation and aggregation of bile acids by subsequent inflammatory responses. …”
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224549
Supplementary file 1_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.docx
Published 2025“…Despite notable changes in biomass, cell wall biomass was only slightly affected. Under drought, a 14% reduction in cell wall biomass was observed alongside compositional changes, including reduced arabinosylation in glucuronoarabinoxylan (GAX). …”
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224550
DataSheet1_Eucommia, Cuscuta, and Drynaria Extracts Ameliorate Glucocorticoid-Induced Osteoporosis by Inhibiting Osteoclastogenesis Through PI3K/Akt Pathway.xlsx
Published 2022“…<p>Osteoporosis is one of the most common diseases in the world which resulted in heavy socioeconomic burden and a public health threat. Glucocorticoid-induced osteoporosis (GIO) is the most common secondary reason of osteoporosis. …”
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224551
Data_Sheet_1_Reno-Protective Effect of Low Protein Diet Supplemented With α-Ketoacid Through Gut Microbiota and Fecal Metabolism in 5/6 Nephrectomized Mice.xlsx
Published 2022“…</p>Conclusion<p>LKD had a better effect than LPD on delaying renal failure in 5/6 nephrectomy-induced CKD, which may be due to the regulation of affecting the gut microbiome and fecal metabolic profiles.…”
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224552
Image1_Arbuscular mycorrhizal fungi alleviate Mn phytotoxicity by altering Mn subcellular distribution and chemical forms in Lespedeza davidii.tif
Published 2024“…</p>Methods<p>In this study, Lespedeza davidii inoculated with or without AMF (Glomus mosseae) under different Mn concentrations (0 mmol/L, 1 mmol/L, 5 mmol/L, 10 mmol/L, and 20 mmol/L) was cultivated via a pot experiment, and plant biomass, physiological and biochemical characteristics, manganese absorption, subcellular distribution, and chemical forms of Mn were examined.…”
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224553
Table_1_Altered Patterns of the Fractional Amplitude of Low-Frequency Fluctuation and Functional Connectivity Between Deficit and Non-Deficit Schizophrenia.docx
Published 2019“…<p>Objective: A limited number of studies have previously reported on the regional activity [amplitude of low-frequency fluctuation (ALFF)] and functional integration [functional connectivity (FC)] of the whole brain in deficit schizophrenia (DS). …”
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224554
Expression of <i>nNOS</i> and <i>PGP 9</i>.<i>5</i> mRNA and nNOS protein.
Published 2017“…<p>(A) The expression of <i>nNOS</i> mRNA measured by real-time PCR decreased with age. …”
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224555
Transverse sections of stems from two month old wild-type and <i>35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i> knockdown <i>Populus</i>.
Published 2011“…<p>(a) Section from fourth internode of wild-type <i>Populus</i> stem during primary growth. …”
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224556
<i>VHL-KO</i> mice exhibit hypoglycemia despite normal glucose tolerance and intact pancreatic β cells.
Published 2013“…<p>(<b>A</b>) <i>VHL-KO</i> mice had significant decreases in blood glucose levels (BS) after tamoxifen injection (4 mg/mouse; n = 10). …”
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224557
Supplementary file 1_Analysis of the diagnostic value of peripheral blood immune inflammatory indicators of female bladder pain syndrome.zip
Published 2025“…According to the correlation analysis between peripheral blood immune-inflammatory markers and disease diagnosis, this research further verifies the potential diagnostic value of peripheral blood inflammatory markers in FBPS.</p>Method<p>A total of 149 women with bladder pain syndrome who visited the urology department of our hospital from January 2013 to December 2024 and 149 healthy controls Patients who underwent health examinations at the physical examination center of our hospital from January 2022 to January 2023 were screened. …”
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224558
Image_2_Efficacy and safety of anti-vascular endothelial growth factor agents in the treatment of primary pterygium.JPEG
Published 2023“…Both topical (RR 0.19, 95% CI 0.08–0.45, P < 0.001) and subconjunctival anti-VEGF agents (RR 0.64, 95% CI 0.45–0.91, P = 0.01) had a positive influence on recurrence. There was no statistically significant difference in complications between the groups (RR 0.80, 95% CI 0.52–1.22, P = 0.29).…”
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224559
S1 Raw data -
Published 2025“…Dapagliflozin increased serum GSH-Px and SOD levels and decreased IL-1β, IL-6, TNF-α and MDA levels (P < 0.05) in a rabbit model of heart failure. …”
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224560
Image_1_Efficacy and safety of anti-vascular endothelial growth factor agents in the treatment of primary pterygium.JPEG
Published 2023“…Both topical (RR 0.19, 95% CI 0.08–0.45, P < 0.001) and subconjunctival anti-VEGF agents (RR 0.64, 95% CI 0.45–0.91, P = 0.01) had a positive influence on recurrence. There was no statistically significant difference in complications between the groups (RR 0.80, 95% CI 0.52–1.22, P = 0.29).…”