Increases in the gain of Ia afferent feedback (i.e., larger presynaptic control level) decrease low-frequency force variability (1-5 Hz) while they increase physiological tremor (5-12 Hz). by Akira Nagamori (4743981)

“…<p>All of the dependent variables are normalized to their respective mean values at the presynaptic control level of -0.5. (A) Mean force power within the common drive range (mean ± SE across 20 trials). …”

TGFβ1 and COL1A1 expression was decreased and RASAL1 expression was increased by Western blotting in NTM cells under both normoxic and hypoxic conditions. by Fiona McDonnell (2636635)

“…NTM cells were treated with 0.3μM 5-aza for 24 hours and then subjected to 1%O₂ for the last 6 hours of treatment. We found that COL1A1 protein was decreased in the presence of 5-aza. …”

The CtrA level decreases upon depletion of CckA and ChpT. by Oliver Leicht (8755473)

A Two-Year Randomized Trial of Interventions to Decrease Stress Hormone Vasopressin Production in Patients with Meniere’s Disease—A Pilot Study by Tadashi Kitahara (702040)

“…Because mental/physical stress and subsequent increase in the stress hormone vasopressin supposedly trigger Meniere's disease, we set a pilot study to seek new therapeutic interventions, namely management of vasopressin secretion, to treat this disease. …”

Glycine is able to induce both a motility speed in- and decrease during zebrafish neuronal migration by Ulrike Theisen (4734555)

Choroidal Neovascularization Is Inhibited in Splenic-Denervated or Splenectomized Mice with a Concomitant Decrease in Intraocular Macrophage by Xue Tan (2994324)

5-FU induces a decrease in the total cell number in cultures of smooth muscle cells. by Marcelo de Carvalho Filgueiras (408321)

“…Quantification of the number of nuclei per field revealed that 5-FU treatment induced a decrease in cell number in all the concentrations tested (<b>G</b>). …”

Image_3_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Table_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.DOCX by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Image_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Video_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Video_3_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Image_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Video_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Table_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.docx by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Aβ42 increases the level of tau in the cytosol and decreases the level of microtubule-bound tau. by Kanae Ando (1951501)

Improved high sensitivity screen for Huntington disease using a one-step triplet-primed PCR and melting curve assay by Mingjue Zhao (654744)

“…To address this pitfall, we have developed an improved screening assay coupling TP-PCR, which has been shown in CE-based assays to detect all expanded alleles regardless of size, with MCA in a rapid one-step assay. …”

Global FD Code ProcB copy from Tropical mammal functional diversity increases with productivity but decreases with anthropogenic disturbance by Daniel Gorczynski (10093617)

“…A variety of factors can affect the biodiversity of tropical mammal communities, but their relative importance and directionality remain uncertain. …”

Silencing of Rap1A decreases ERK and p38 activation. by Yougen Wu (830191)

Decreased miR-29b/c in GC tissue samples. by He Cui (229445)