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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
larger decrease » marked decrease (Expand Search)
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4581
Exploring the Shape Influence on Melting Temperature, Enthalpy, and Solubility of Organic Drug Nanocrystals by a Thermodynamic Model
Published 2017“…This paper focuses on a thermodynamic model built to predict the reduction of organic drug melting temperature and enthalpy with nanocrystal size decrease. …”
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4582
Model.
Published 2019“…The precise reason for this decreased mitotic timing is still unknown but we hypothesize that cells with sufficient CENP-A recruit SAC components more quickly or capture microtubules more efficiently to satisfy the SAC faster. …”
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4583
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4584
Knockout of <i>Il2rg</i> and <i>Rag2</i> caused deficient development of lymphocytes.
Published 2022Subjects: -
4585
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4586
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4587
Percent changes (Δ-values are differences between means) in protein levels and proteolytic activity of Separase after IM treatment when compared to corresponding untreated cells.
Published 2015“…<p><sup>1</sup> Δ-values were calculated from significant data sets diagrammed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0129648#pone.0129648.g001" target="_blank">Fig 1</a>. …”
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4588
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4589
Decreases in Gap Junction Coupling Recovers Ca<sup>2+</sup> and Insulin Secretion in Neonatal Diabetes Mellitus, Dependent on Beta Cell Heterogeneity and Noise
Published 2016“…Previously, we demonstrated that a critical number of inexcitable cells can rapidly suppress the overall islet response, as a result of gap junction coupling. …”
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4590
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4591
SAHA Decreases HDAC 2 and 4 Levels <em>In Vivo</em> and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease
Published 2011“…To elucidate whether SAHA is a potent modifier of HDAC protein levels <em>in vivo</em>, we performed two independent mouse trials. …”
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4592
Identification of Chz1 regions dictates the preference for H2A.Z. (A) Schematic view of Chz1-FL according to a previous mapping result.
Published 2019“…(C) Effect of Chz1-MC and Chz1-M on dictating the preference for H2A.Z. The folds of binding affinity decrease between all histone dimers (in single-chain form) and scZB are denoted as Kd/Kd (H2A.Z) and calculated for comparison. …”
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4593
Image_1_Chronic Exposure to the Combination of Cigarette Smoke and Morphine Decreases CD4+ Regulatory T Cell Numbers by Reprogramming the Treg Cell Transcriptome.tif
Published 2022“…We then performed RNA-Seq on Treg cells from mice treated with SM, M, or SM + M, and we found that the S + M induced a number of significant changes in the transcriptome, that were not as apparent following treatment with either SM or M alone. …”
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4594
Supplementary Material for: Vitamin D<sub>3</sub> Treatment Decreases Frequencies of CD16-Positive and TNF-α-Secreting Monocytes in Asthmatic Patients
Published 2015“…<b><i>Background:</i></b> Previously, we demonstrated that glucocorticoid (GC) treatment of asthmatic patients resulted in decreasing frequencies of monocyte subsets expressing CD16 and capable of releasing TNF-α. …”
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4595
Effects of Pressure Support Ventilation Mode on Emergence Time and Intra-Operative Ventilatory Function: A Randomized Controlled Trial
Published 2014“…<div><p></p><p>We tested the hypothesis that pressure-support ventilation (PSV) allows a reduction in emergence time and laryngeal mask airway (LMA) removal time after general anesthesia compared to volume-controlled mechanical ventilation (CMV). …”
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4596
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4597
PACAP Protects Adult Neural Stem Cells from the Neurotoxic Effect of Ketamine Associated with Decreased Apoptosis, ER Stress and mTOR Pathway Activation
Published 2017“…The results also suggest that the effect of ketamine occurs <i>via</i> AMPA receptor activation. Finally, we show that PACAP counteracted the decreased NSC viability induced by ketamine <i>via</i> the specific activation of the PAC-1 receptor subtype. …”
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4598
DataSheet_1_Patients with juvenile idiopathic arthritis have decreased clonal diversity in the CD8+ T cell repertoire response to influenza vaccination.pdf
Published 2024“…At the clonotype level, the response to the conserved influenza antigen, M1<sub>58–66</sub> has been well characterized in healthy individuals, but not in patients receiving immunosuppressive therapy or with aberrant immunity, such as those with juvenile idiopathic arthritis (JIA). Here we show that patients with JIA have a reduced number of M1<sub>58–66</sub> specific RS/RA clonotypes, indicating decreased clonal richness and, as a result, have lower repertoire diversity. …”
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4599
DataSheet_1_Patients with juvenile idiopathic arthritis have decreased clonal diversity in the CD8+ T cell repertoire response to influenza vaccination.pdf
Published 2024“…At the clonotype level, the response to the conserved influenza antigen, M1<sub>58–66</sub> has been well characterized in healthy individuals, but not in patients receiving immunosuppressive therapy or with aberrant immunity, such as those with juvenile idiopathic arthritis (JIA). Here we show that patients with JIA have a reduced number of M1<sub>58–66</sub> specific RS/RA clonotypes, indicating decreased clonal richness and, as a result, have lower repertoire diversity. …”
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4600