RAGE deficient mice displayed decreased levels of circulating IL-17A in septic arthritis whereas healthy mice had increased levels of several pro-inflammatory cytokines. by Majd Mohammad (764517)

Minimum Margin of stability. by Mengnan Wu (769253)

DataSheet1_Interactive Effects of Glucocorticoids and Cytochrome P450 Polymorphisms on the Plasma Trough Concentrations of Voriconazole.docx by Su-jie Jia (10869666)

“…The mutation of CYP3A5 has no significant effect. Furthermore, CYP2C19*17 mutants could strengthen the effects of glucocorticoids and decrease VRC C_min/dose to a larger extent.…”

Image_1_Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19.tif by Tanja M. Müller (10026137)

“…</p>Conclusion<p>COVID-19 is associated with a decrease in circulating adaptive immune cells expressing the key gut homing marker α4β7 suggesting that these cells are preferentially recruited to extra-intestinal tissues independently of α4β7 or that the systemic immune response against SARS-CoV-2 is at least numerically dominated by extraintestinal, particularly pulmonary, immune cell priming.…”

Image_2_Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19.tif by Tanja M. Müller (10026137)

“…</p>Conclusion<p>COVID-19 is associated with a decrease in circulating adaptive immune cells expressing the key gut homing marker α4β7 suggesting that these cells are preferentially recruited to extra-intestinal tissues independently of α4β7 or that the systemic immune response against SARS-CoV-2 is at least numerically dominated by extraintestinal, particularly pulmonary, immune cell priming.…”

Image_4_Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19.tif by Tanja M. Müller (10026137)

“…</p>Conclusion<p>COVID-19 is associated with a decrease in circulating adaptive immune cells expressing the key gut homing marker α4β7 suggesting that these cells are preferentially recruited to extra-intestinal tissues independently of α4β7 or that the systemic immune response against SARS-CoV-2 is at least numerically dominated by extraintestinal, particularly pulmonary, immune cell priming.…”

Image_3_Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19.tif by Tanja M. Müller (10026137)

“…</p>Conclusion<p>COVID-19 is associated with a decrease in circulating adaptive immune cells expressing the key gut homing marker α4β7 suggesting that these cells are preferentially recruited to extra-intestinal tissues independently of α4β7 or that the systemic immune response against SARS-CoV-2 is at least numerically dominated by extraintestinal, particularly pulmonary, immune cell priming.…”

ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation by Baby Periyanayaki Muthusamy (838234)

“…TGF-β also activates the Erk MAPK pathway through recruitment and Tyr phosphorylation of the adaptor protein ShcA by the activated TGF-β type I receptor. We found that ShcA protects the epithelial integrity of nontransformed cells against EMT by repressing TGF-β-induced, Smad-mediated gene expression. p52ShcA competed with Smad3 for TGF-β receptor binding, and down-regulation of ShcA expression enhanced autocrine TGF-β/Smad signaling and target gene expression, whereas increased p52ShcA expression resulted in decreased Smad3 binding to the TGF-β receptor, decreased Smad3 activation, and increased Erk MAPK and Akt signaling. …”

Data_Sheet_1_Plantaricin BM-1 decreases viability of SW480 human colorectal cancer cells by inducing caspase-dependent apoptosis.docx by He Wang (250350)

Reduction of Nonvolatile Particulate Matter Emissions of a Commercial Turbofan Engine at the Ground Level from the Use of a Sustainable Aviation Fuel Blend by Lukas Durdina (1482799)

“…These emissions can be reduced using sustainable aviation fuels (SAFs). Here, we investigate the effects of a 32% SAF blend with fossil fuel on particle size distributions and nvPM emission indices of a widely used turbofan engine. …”

Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma by Deepanwita Sengupta (734845)

“…BET inhibitor JQ1 disrupts BRD4 association with super-enhancers, downregulates proto-oncogenes, such as <i>c-Myc</i>, and displays antitumor activity in preclinical animal models of human cancers. Here we show that an enhancer proximal to the <i>c-Myc</i> promoter is enriched in H3K27Ac and associated with high occupancy of BRD4, and coincides with a putative <i>c-Myc</i> super-enhancer in MCC cells. …”

Table_1_Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl– Cotransporter NCC and Transiently Affects Sodium Handling.DOCX by Jérémie Canonica (7240793)

Table_1_Decreased Functional Connectivity Between the Left Amygdala and Frontal Regions Interferes With Reading, Emotional, and Executive Functions in Children With Reading Difficu... by Ohad Nachshon (8771906)

“…Introduction<p>Dyslexia is a reading disorder characterized by significant difficulty in reading, as well as reports of altered executive functions (EF). …”

Table_2_Decreased Functional Connectivity Between the Left Amygdala and Frontal Regions Interferes With Reading, Emotional, and Executive Functions in Children With Reading Difficu... by Ohad Nachshon (8771906)

“…Introduction<p>Dyslexia is a reading disorder characterized by significant difficulty in reading, as well as reports of altered executive functions (EF). …”

image1_Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma.tif by Tingting Jia (770327)

Presentation_1_Decreased resistance to bacterial cold-water disease and excessive inflammatory response in ayu (Plecoglossus altivelis) reared at high water temperature.pptx by Goshi Kato (5772416)

“…</p>Discussion<p>These results suggest that rearing the fish under high water temperature causes excessive inflammatory responses similar to metabolic inflammation in human obesity, resulting in a decrease of disease resistance. In addition, thymic involution induced by higher water temperature probably leads the poor response to vaccination. …”

Table_1_Decreased resistance to bacterial cold-water disease and excessive inflammatory response in ayu (Plecoglossus altivelis) reared at high water temperature.docx by Goshi Kato (5772416)

“…</p>Discussion<p>These results suggest that rearing the fish under high water temperature causes excessive inflammatory responses similar to metabolic inflammation in human obesity, resulting in a decrease of disease resistance. In addition, thymic involution induced by higher water temperature probably leads the poor response to vaccination. …”

Decreased Pre-existing Ad5 Capsid and Ad35 Neutralizing Antibodies Increase HIV-1 Infection Risk in the Step Trial Independent of Vaccination by Cheng Cheng (68821)

“…Those Ad5 seropositive subjects who generated anti-capsid responses showed a marked reduction in vaccine-induced CD8 responses. …”

Data_Sheet_1_The role of booster vaccination in decreasing COVID-19 age-adjusted case fatality rate: Evidence from 32 countries.docx by Cui Zhou (1388874)

Examples of alluvial plots indicating frequency change of people performing group activity, cultural activity and keeping up with world affairs among the repeated measures (N = 203... by Lan Li (73597)