<i>Y. pseudotuberculosis</i> lacking a functional IscR display decreased transcription of a number of pYV encoded genes. by Halie K. Miller (375675)

“…<p>Middle and inner rings: heatmap <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004194#ppat.1004194-Krzywinski1" target="_blank">[83]</a> representations of log₂-ratios (log₂(RPKM_mutant/RPKM_wt) for each gene on the pYV plasmid for both the Δ<i>iscR</i> (middle ring) and apo-IscR (inner ring) mutants relative to wild type. …”

Huperzine A decreased HiLyte-Aβ₄₂ fluorescent signals colocalized with mitochondrial marker in primary rat neurons. by Yun Lei (495070)

Loss of RBM-26 causes mitochondria dysfunction in PLM. by Tamjid A. Chowdhury (14149846)

Role of Solvent Water in the Temperature-Induced Self-Assembly of a Triblock Copolymer by Achintya Kundu (1308561)

“…Our experimental results suggest two distinct subpopulations of water molecules: those that interact with other water molecules and those involved in the hydration of a triblock copolymer surface. We find that the vibrational dynamics of bulk-like water is not affected by either micellation or gelation of triblock copolymers. …”

Decreased by Violet R. Mukaro (282939)

<i>In vitro</i> characterization of escape mutant viruses of anti-HA stalk antibody candidate clone F11. by Kaori Sano (229641)

“…<p>Two escape mutant viruses of antibody clone F11 were obtained by serial passage of A/Narita/1/2009 (H1N1)pdm09 virus in the presence of high concentrations of F11 IgG1. …”

Expression of KIF4A in shKIF4A cells. by Yasuyuki Minakawa (502260)

“…(<b>B</b>) Immunoblotting analysis shows that the KIF4A protein levels in shKIF4A-transfected cells (HSC-3- and Ca9-22-derived transfectants; 2 clones each) also have decreased markedly compared with that in the shMock cells (<i>P</i> < 0.05, Mann-Whitney U test).…”

Dual Stimuli-Responsive Pickering Emulsions from Novel Magnetic Hydroxyapatite Nanoparticles and Their Characterization Using a Microfluidic Platform by Shruti Mendiratta (1504402)

“…Here, we report the synthesis of novel “smart” hydroxyapatite (HaP) magnetic nanoparticles and their corresponding stimuli-responsive Pickering emulsions and explore their movement under confined spaces using a microfluidic platform. …”

Increasing temperature decreases oxygen concentration and decreasing oxygen content decreases neuronal excitability. by Yuguo Yu (172221)

“…Increasing temperature can dramatically decrease oxygen levels. B. Response of layer 2/3 pyramidal cells (n = 5) to the intracellular injection of a depolarizing current pulse (200 pA, 500 ms) at different temperatures (same experiments as in A). …”

Data_Sheet_1_Decreased plasma fetuin-A level as a novel bioindicator of poor prognosis in community-acquired pneumonia: A multi-center cohort study.docx by Lili Zhao (442802)

“…Fetuin-A levels were decreased in patients with CAP, especially in SCAP and non-survivors. …”

Decreased macrophage recruitment correlates with decreased angiogenesis. by Johanna R. Reed (306158)

“…<p>A) Quantification of BrdU incorporation demonstrates that decreased macrophage infiltration does not significantly correlate with a change in epithelial cell proliferation (N.S. = not significant). …”

International Patent Classification (IPC) scheme for a generic patent classified as <i>A01C 3/04</i>. by Edoardo Filippi-Mazzola (14817626)

A homozygous missense variant in <i>VWA2</i>, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux by Amelie T. van der Ven (4782093)

“…We identified a homozygous missense mutation (c.1336C>T, p.Arg446Cys) in the gene <i>Von Willebrand factor A domain containing 2</i> (<i>VWA2</i>). …”

A summary of the included study characteristics. by Zahra Tajik (20752452)

“…Also, the mean GCF level of diabetic patients decreased after NSPT. Therefore, visfatin level may be used as a diagnostic and therapeutic noninvasive biomarker in patients with periodontitis, which requires further studies.…”

Geographical distribution of large cities and small cities. by Saul Estrin (8629173)

“…The Figure reveals two patterns: 1) the maximum level of innovation is higher in large cities (2.53) than in small cities (2.02); 2) among large cities in <b>a</b>, innovation levels in general decrease with nightlight density. …”

MrcA disruption or ITPR3 depletion decreases pT853-MYPT1 and pS19-MLC2 recruitment to chlamydial inclusion. by Phu Hai Nguyen (4967140)

Clostridium difficile toxins or infection induce upregulation of adenosine receptors and IL-6 with early pro-inflammatory and late anti-inflammatory pattern by D.A. Foschetti (10461345)

“…<div><p>Clostridium difficile causes intestinal inflammation, which increases adenosine. We compared the expression of adenosine receptors (AR) subtypes A1, A2A, A2B, and A3 in HCT-8, IEC-6 cells, and isolated intestinal epithelial cells, challenged or not with Clostridium difficile toxin A and B (TcdA and TcdB) or infection (CDI). …”

Model of intrastriatal network during cocaine and A2A-R antagonists exposure. by Alessandro Tozzi (246297)

“…The simultaneous effect of the stimulation of D2-Rs by DA and the blockade of A2A-Rs by CSC or ZM, on cholinergic interneurons might decrease the release of acetylcholine at the synaptic sites of D2-and D1-R expressing MSNs. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”