Image_2_Decreased MEF2A Expression Regulated by Its Enhancer Methylation Inhibits Autophagy and May Play an Important Role in the Progression of Alzheimer’s Disease.TIF by Hui Li (32376)

Data_Sheet_1_O-GlcNAcylation Suppresses the Ion Current IClswell by Preventing the Binding of the Protein ICln to α-Integrin.docx by Roberta Costa (4117369)

“…Here, we show that experimentally increased O-GlcNAcylation of cellular proteins inhibited the endogenous as well as the ICln-induced IClswell current and prevented RVD in a human renal cell line, while decreases in O-GlcNAcylation augmented the current magnitude. …”

Wnt5a Regulates the Assembly of Human Adipose Derived Stromal Vascular Fraction-Derived Microvasculatures by Venkat M. Ramakrishnan (2559520)

“…We exposed hSVF cells to a battery of angiogenesis inhibitors and found that the pan-Wnt inhibitor IWP2 produced the most significant hSVF-EC networking decrease (~25%). …”

<i>Delonix regia</i> Leaf Extract (DRLE): A Potential Therapeutic Agent for Cardioprotection by Lung-Shuo Wang (3391244)

“…We suggest that DRLE may act as a promising novel herbal medicine for cardioprotection.…”

Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling by Colin H. Beckwitt (2037196)

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X‑ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson’s Disease Mouse Model by Jun Mou (4113313)

“…In a MPTP-induced Parkinson’s disease (PD) mouse model, <b>BI-43</b> manifested efficacy in mitigating locomotor deficits through reversing dopaminergic neuronal loss, reducing microglia, and decreasing levels of the sQC/gQC substrates, α-synuclein, and CCL2. …”

Variation of the time window of detection with recombination. by Gabriele Pedruzzi (5753792)

The optimization algorithm to identify ideal conditions for detection of epistasis is exemplified through the 3D scatter plot of three different measures of LD. by Gabriele Pedruzzi (5753792)

FABP5 expression levels in brain microvessels from 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

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Cellular uptake of [¹⁴C]docosahexaenoic acid (DHA) by RBECs transfected with MFSD2A siRNA. by Takuro Iwao (14636741)

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Brain uptake rate of [¹⁴C]docosahexaenoic acid (DHA) in the whole brain and each brain region. by Takuro Iwao (14636741)

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Brain uptake rate of [¹⁴C]sucrose in the whole brain and individual brain regions. by Takuro Iwao (14636741)

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Brain uptake of [³H]mannitol in 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

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Brain uptake of [¹⁴C]docosahexaenoic acid (DHA) in 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

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The mRNA expression levels of Mfsd2a in brain microvessels from 2- and 24-month-old mice. by Takuro Iwao (14636741)

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MFSD2A expression levels in brain microvessels from 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

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Mutations of Human <i>NARS2</i>, Encoding the Mitochondrial Asparaginyl-tRNA Synthetase, Cause Nonsyndromic Deafness and Leigh Syndrome by Mariella Simon (711384)

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Detection of epistasis is rescued by simultaneous analysis of multiple independently-evolved populations. by Gabriele Pedruzzi (5753792)

MiR-34a regulates the invasive capacity of canine osteosarcoma cell lines by Cecilia M. Lopez (4729986)

“…Lastly, we validated changes in miR-34a putative target gene expression, including decreased expression of KLF4, SEM3A, and VEGFA transcripts in canine OSA cells overexpressing miR-34a and identified KLF4 and VEGFA as direct target genes of miR-34a. …”

Serum Magnesium and Sudden Death in European Hemodialysis Patients by Camiel L. M. de Roij van Zuijdewijn (829813)

“…Furthermore, data on the association between serum Mg and sudden death in this patient group is limited. Therefore, we evaluated Mg in a <i>post-hoc</i> analysis using pooled data from the CONvective TRAnsport STudy (CONTRAST, NCT00205556), a randomized controlled trial (RCT) evaluating the survival risk in dialysis patients on hemodiafiltration (HDF) compared to HD with a mean follow-up of 3.1 years. …”