MMV291 disrupts actin-dependent apicoplast segregation and induces a partial delayed death phenotype. by Madeline G. Dans (14193815)

“…<b>ii</b> These images were quantified by 3 independent blind scorers, which showed a significant decrease in the normal segregation of apicoplasts between the 10 μM MMV291 and DMSO treatments, while the 5 μM MMV291 was not significant (ns). …”

Knockdown of Appa, Appb, or Prp1 results in impaired development and death of head region. A–L. by Darcy M. Kaiser (114856)

“…S3</a>). The <i>appa</i> and <i>appb</i> splice blocking (SB) MOs used above (A–H) significantly decreases detection of protein species by the antibody 22C11 (top row). …”

Stabilization of p27^Kip1 through S140 phosphorylation is required for tumorsphere resistance to IR. by Erica K. Cassimere (3111996)

“…Differences between groups were evaluated using two-tailed Student <i>t</i> tests among replicate experiments; **P = 0.005. (E) p27S140A has a decreased half-life compared to p27WT in tumorspheres subjected to IR. …”

mGluR1 facilitates anchorage-independent growth. by Malathi Banda (505556)

“…<p><b>A and B. MCF10AT1 cells.</b> Cells were transduced with either with pLenti-<i>GRM1</i>, pLenti-<i>LacZ</i>, sh<i>GRM1</i>, or NS control vector and stably selected before plating in soft agar. …”

Dual Involvement of Growth Arrest-Specific Gene 6 in the Early Phase of Human IgA Nephropathy by Kojiro Nagai (226911)

“…Meanwhile, representative cell cycle regulatory protein p27 has been reported to be expressed in podocytes in normal glomeruli with decreased expression in proliferating glomeruli, which inversely correlated with mesangial proliferation in human IgA nephropathy (IgAN).…”

Table_2_Causal effects of fatty acids on atopic dermatitis: A Mendelian randomization study.XLSX by Jia-Ying Lin (2247670)

“…The single-SNP analyses revealed that n-3 fatty acids are likely linked to a decreased risk of AD through FADS cluster, highlighting the significance of the FADS gene in the fatty acids synthesis pathway in the development of AD.…”

Reappraisal of Metformin Efficacy in the Treatment of Type 2 Diabetes: A Meta-Analysis of Randomised Controlled Trials by Rémy Boussageon (172049)

“…We cannot exclude a 33% reduction or a 64% increase in cardiovascular mortality. …”

Table_1_Causal effects of fatty acids on atopic dermatitis: A Mendelian randomization study.XLSX by Jia-Ying Lin (2247670)

“…The single-SNP analyses revealed that n-3 fatty acids are likely linked to a decreased risk of AD through FADS cluster, highlighting the significance of the FADS gene in the fatty acids synthesis pathway in the development of AD.…”

Image_1_Causal effects of fatty acids on atopic dermatitis: A Mendelian randomization study.jpeg by Jia-Ying Lin (2247670)

“…The single-SNP analyses revealed that n-3 fatty acids are likely linked to a decreased risk of AD through FADS cluster, highlighting the significance of the FADS gene in the fatty acids synthesis pathway in the development of AD.…”

Table_3_Causal effects of fatty acids on atopic dermatitis: A Mendelian randomization study.XLSX by Jia-Ying Lin (2247670)

“…The single-SNP analyses revealed that n-3 fatty acids are likely linked to a decreased risk of AD through FADS cluster, highlighting the significance of the FADS gene in the fatty acids synthesis pathway in the development of AD.…”

In vivo performance of FRCaMPi and SomaFRCaMPi in neurons in zebrafish larvae. by Shihao Zhou (5774795)

“…<b>(B)</b> Representative single plane confocal images of periventricular cell bodies in optic tectum of fish expressing jRGECO1a, FRCaMPi or SomaFRCaMPi. Decreased neuropil fluorescence and clearer neuronal cell bodies was found in SomaFRCaMPi-expressing larval zebrafish. …”

Table_1_Soil uptake of isoprenoids in a Eucalyptus urophylla plantation forest in subtropical China.DOCX by Zhaobin Mu (12571636)

“…The removal of surface litter had a significant impact on the exchange rates of two monoterpenes (α-pinene and β-pinene), resulting in decreased fluxes. …”

Data_Sheet_1_Impact of a multidomain lifestyle intervention on regional spontaneous brain activity.docx by So Young Moon (12981504)

“…Our results suggest that facility-based group preventive strategies may have cognitive benefits through neuroplastic changes in functional processing circuits in the brain areas which play a crucial role in the adaptive learning and internally directed cognition.…”

Defect-Induced Band-Edge Reconstruction of a Bismuth-Halide Double Perovskite for Visible-Light Absorption by Adam H. Slavney (1415035)

“…The first halide double perovskite evaluated as an absorber, Cs₂AgBiBr₆ (<b>1</b>), has a bandgap of 1.95 eV. Here, we show that dilute alloying decreases <b>1</b>’s bandgap by ca. 0.5 eV. …”

Image 1_Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study.jpeg by Bhaswati Roy (2802559)

“…Surgery induced further gray matter volume and brain tissue changes along with reduced cognitive scores within the immediate postoperative period (MoCA 26 vs 24, P < 0.001). At six months, we observed reversal of brain alterations for most patients and a concomitant rebound of cognitive scores to patient’s baseline status.…”

Image_1_A Mycobacterium tuberculosis Specific IgG3 Signature of Recurrent Tuberculosis.tiff by Stephanie Fischinger (9528578)

“…Individuals with recurrent TB had decreased Mtb-antigen specific IgG3 titers, but not other IgG subclasses or IgA, compared to control individuals. …”

Video_2_Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model.MOV by Ravikanth Velagapudi (7880072)

“…In a separate cohort we evaluated neuroinflammation and blood-brain barrier (BBB) dysfunction using clarified brain tissue with light-sheet microscopy. …”

Mice deficient in NKLAM have attenuated inflammatory cytokine production in a Sendai virus pneumonia model by Donald W. Lawrence (4923328)

“…Here, we present novel data describing a role for NKLAM in regulating the immune response to Sendai virus (SeV), a murine model of paramyxoviral pneumonia. …”

Improving Degradation Efficiency of Organic Pollutants through a Self-Powered Alternating Current Electrocoagulation System by Linglin Zhou (1626217)

“…Moreover, the removal efficiency can be further enhanced by decreasing the frequency AC, in which a 5.7-fold improvement was achieved at 0.2 Hz compared to DC at 1.8 Hz. …”

Image_1_Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model.TIFF by Ravikanth Velagapudi (7880072)

“…In a separate cohort we evaluated neuroinflammation and blood-brain barrier (BBB) dysfunction using clarified brain tissue with light-sheet microscopy. …”