Image_4_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Image_3_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Image_2_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Image_1_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Table_1_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.DOC by Jie-Jie Shen (5600129)

“…Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Serum Creatinine Modifies Associations between Body Mass Index and Mortality and Morbidity in Prevalent Hemodialysis Patients by Yukitoshi Sakao (2547880)

Subjects:

Exploring reopening strategies for a wide range in disease transmission <i>v</i>_<i>r</i> with high testing capacity <i>T</i>_<i>r</i> = 0.75: We randomly choos... by Mackenzie Dalton (14093874)

Data_Sheet_2_Centrally Acting Angiotensin-Converting Enzyme Inhibitor Suppresses Type I Interferon Responses and Decreases Inflammation in the Periphery and the CNS in Lupus-Prone... by Cassandra Nocito (9377072)

“…It is known that ACE degrades bradykinin (BK) into inactive peptides. We have previously shown in an in vitro model of mouse bone-marrow-derived dendritic cells (BMDC) and human peripheral blood mononuclear cells that captopril (a centrally acting ACE inhibitor-ACEi) suppressed Type I IFN responsive gene (IRG) expression. …”

Data_Sheet_3_Centrally Acting Angiotensin-Converting Enzyme Inhibitor Suppresses Type I Interferon Responses and Decreases Inflammation in the Periphery and the CNS in Lupus-Prone... by Cassandra Nocito (9377072)

“…It is known that ACE degrades bradykinin (BK) into inactive peptides. We have previously shown in an in vitro model of mouse bone-marrow-derived dendritic cells (BMDC) and human peripheral blood mononuclear cells that captopril (a centrally acting ACE inhibitor-ACEi) suppressed Type I IFN responsive gene (IRG) expression. …”

Data_Sheet_1_Centrally Acting Angiotensin-Converting Enzyme Inhibitor Suppresses Type I Interferon Responses and Decreases Inflammation in the Periphery and the CNS in Lupus-Prone... by Cassandra Nocito (9377072)

“…It is known that ACE degrades bradykinin (BK) into inactive peptides. We have previously shown in an in vitro model of mouse bone-marrow-derived dendritic cells (BMDC) and human peripheral blood mononuclear cells that captopril (a centrally acting ACE inhibitor-ACEi) suppressed Type I IFN responsive gene (IRG) expression. …”

Multivariate-adjusted odds ratios for all-cause mortality according to the BMI groups and the tertiles of serum Cr. by Yukitoshi Sakao (2547880)

Subjects:

pPplA enhances bacterial aggregation in broth culture. by Bobbi Xayarath (209925)

“…<p><b>(A)</b> Image of bacterial aggregation observed between the wild-type <i>L</i>. …”

Proteasome inhibition during early postnatal development provokes a decrease in the expression of mitochondrial markers and an increase in DNA oxidation. by Rocío Romero-Granados (193152)

Deletion of <i>Trgal11</i> resulted in a significant decrease in the transcription of cellobiohydrolase and endoglucanase but not β-glucosidase genes. by Fanglin Zheng (4844064)

Table_1_Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption.docx by Sven de Mey (5813789)

Scatterplot showing the decrease in individual core mass caused by the removal of a flake, relative to reduction interval (blow number). by Mark W. Moore (3155967)

“…<p>Scatterplot showing the decrease in individual core mass caused by the removal of a flake, relative to reduction interval (blow number).…”

Deep crypt secretory (DCS) cells are predominantly distributed in the proximal colon, with a progressive decrease towards the distal colon. by Daisuke Sugahara (2047696)

Decrease in cell migration and adhesion of MCF10A cells after knockdown of <i>MYO1C</i>. by Kittichate Visuttijai (3204519)

“…A dose-dependent decrease in relative cell index response to MYO1C depletion was observed reaching to a significant value with concentrations of 5 and 10 nM of <i>MYO1C</i>-siRNA at 48 hours post-transfection compared to control cells (mock transfection). …”

Substrate translocation via Mep2^H194E induces a pH decrease. by Ana Sofia Brito (8463537)

RcbA and RcbB co-operatively decrease motility independent of CaCl₂ concentration. by Shobnom Mustaree (21728815)