Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in <i>Drosophila</i> by Michael A. Najarro (831657)

“…Our goal is to genetically dissect variation in the response to xenobiotics, and characterize naturally-segregating polymorphisms that modulate toxicity. Here, we use the <i>Drosophila</i> Synthetic Population Resource (DSPR), a multiparent advanced intercross panel of recombinant inbred lines, to identify QTL (Quantitative Trait Loci) underlying xenobiotic resistance, and employ caffeine as a model toxic compound. …”

Table1_Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis.DOCX by Michael Horckmans (14206388)

“…Among the mutations identified, we focused our attention on a coding region polymorphism (rs3745601) that results in replacement of the asparagine at residue 178 with threonine (N178T) located in the second extracellular loop of the P2Y₄ receptor. …”

Renal (urea and creatinine) (a, b) and Liver function (ALT and AST) (c, d) test in serums of different experimental groups and body weight changes (e) on day 10. by Omid Mehrpour (9385929)

Subjects:

External capsule MR diffusion properties (mean ± standard deviation) in controls (●) and poly (I:C) rats (○) measured at 4 and 10 weeks after birth. by Lucy Liu (298305)

Corpus callosum MR diffusion properties (mean ± standard deviation) in controls (●) and poly (I:C) rats (○) measured at 4 and 10 weeks after birth. by Lucy Liu (298305)

Internal capsule MR diffusion properties (mean ± standard deviation) in controls (●) and poly (I:C) rats (○) measured at 4 and 10 weeks after birth. by Lucy Liu (298305)

Zebrafish <i>hoxd4a</i> Acts Upstream of <i>meis1.1</i> to Direct Vasculogenesis, Angiogenesis and Hematopoiesis by Aseervatham Anusha Amali (390160)

“…<div><p>Mice lacking the 4^th-group paralog <i>Hoxd4</i> display malformations of the anterior vertebral column, but are viable and fertile. Here, we report that zebrafish embryos having decreased function of the orthologous <i>hoxd4a</i> gene manifest striking perturbations in vasculogenesis, angiogenesis and primitive and definitive hematopoiesis. …”

Ethical dilemma of identity disclosure faced by medical students in clinical clerkships: A nationwide multicenter study in China by Yi Zhao (14034)

“…<div><p>Objective</p><p>Medical students in China are currently facing a dilemma of whether to clarify their identity as students to patients. …”

MicroCT analysis of the lower femoral metaphysis in A) chicken of the FREE group, B) chicken of the HYPO group. by Eric Aguado (687890)

<i>cdx4</i>, <i>meis1.1</i> and Hox gene expression in <i>hoxd4a</i> morphants, and a genetic pathway for specification of hemangioblasts and unipotential stem cells. by Aseervatham Anusha Amali (390160)

“…<p>(A) qRT-PCR showing decreased expression of <i>meis1.1</i> and many, but not all, <i>hox</i> genes in <i>hoxd4a</i> morphants at 26–28 hpf. …”

Limited trypsinolysis of PfGyrA-CTD. by Soshichiro Nagano (826134)

“…<p>Protein digests were visualised as a function of time. Time elapsed in minutes after initiation of reaction is indicated along the top of the gel. …”

AR-induced downstream signaling cascades were recapitulated in membrane-LRs of HUVECs cells, upon KSHV infection. by Xing Wang (154377)

“…<p>(a, b) PP1-induced decreasing expression of pEphA2 at Ser897 is rescued by DHT treatment upon KSHV infection. …”

Membrane-localized AR facilitates productive endocytosis and nuclear trafficking of KSHV. by Xing Wang (154377)

“…(c) Knockdown of AR and EphA2 expression reduces KSHV endocytosis, as indicated by decreasing gB staining in cells. …”

Image1_Prolonged warm ischemia time increases mitogen-activated protein kinase activity and decreases perfusate cytokine levels in ex vivo rat liver machine perfusion.jpeg by Joohyun Kim (413093)

Effects of 6-week ALF or ELD administration in <i>Cyp27b1</i>^<i>+/+</i> or <i>Cyp27b1</i>^{<i>–/–</i>}mice. by Yoshihisa Hirota (616015)

Subjects:

Effect of vitamin D derivatives on the proliferation and the differentiation of ATDC5 cells. by Yoshihisa Hirota (616015)

Subjects:

Bone mineral density and bone strength of the femurs in <i>Cyp27b1</i>^<i>+/+</i> or <i>Cyp27b1</i>^{<i>–/–</i>}mice administered ALF or ELD. by Yoshihisa Hirota (616015)

Subjects:

Appearance and soft X-ray image of the femurs of <i>Cyp27b1</i>^<i>+/+</i> or <i>Cyp27b1</i>^{<i>–/–</i>}mice administered ALF or ELD. by Yoshihisa Hirota (616015)

Subjects:

Bone histology in <i>Cyp27b1</i>^<i>+/+</i> or <i>Cyp27b1</i>^{<i>–/–</i>}mice administered ALF or ELD. by Yoshihisa Hirota (616015)

Subjects:

Structural analysis of trabecular bone of femur of <i>Cyp27b1</i>^<i>+/+</i> or <i>Cyp27b1</i>^{<i>–/–</i>}mice administered ALF and ELD. by Yoshihisa Hirota (616015)

Subjects: