Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

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Transcriptome comparison of HEK293^DAX cells and SupT1^DAX cells. by Jimin Yoon (9646685)

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LV chamber dilation and depressed cardiac function in PTIP- TAC hearts. by Adam B. Stein (743743)

“…However, PTIP- TAC hearts reveal a significant increase in LVEDD (panel A) and a significant decrease in LVEF when compared to PTIP- sham and PTIP+ TAC hearts. …”

ATG13 is a substrate of CDK1/cyclin B in mitosis. by Zhiyuan Li (205620)

“…(C) CDK1 inhibitor RO-3306 decreases the ATG13 band shift in mitosis. HeLa cells synchronized and treated as <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000288#pbio.3000288.g003" target="_blank">Fig 3A</a> were subjected to western blot analysis. …”

ULK1 is a substrate of CDK1/cyclin B in mitosis. by Zhiyuan Li (205620)

Impairment of mossy fiber-CA3 LTP by a sialidase inhibitor. by Akira Minami (474027)

A MFS-like plasma membrane transporter required for <i>Leishmania</i> virulence protects the parasites from iron toxicity by Maria Fernanda Laranjeira-Silva (843978)

“…LIR1 null parasites are more sensitive to iron toxicity and have drastically impaired infectivity, phenotypes that are reversed by <i>LIR1</i> complementation. We conclude that LIR1 functions as a plasma membrane iron exporter with a critical role in maintaining iron homeostasis and promoting infectivity in <i>L</i>. …”

Subcellular localization of NS2 in assembly deficient mutants in NS5A protein. by Costin-Ioan Popescu (230609)

“…(<b>E</b>) Mutations in NS5A protein drastically decrease the number of cells presenting NS2 dotted structures. …”

TGF-β1 down-regulates the expression of CD300a and Eomes in Th1 cells. by Sriram Narayanan (364941)

“…<p>(A) Sorted naïve CD4 T cells were polarized under Th1 or Th17 conditions as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010636#s4" target="_blank">materials and methods</a>. …”

Expression of proteins associated with AD is altered by eIF4A inhibition. by Andrew Bottley (361376)

“…Significant differences (p≤0.05 by t-test) are indicated by asterisks. <b>C</b>. Secreted A-beta levels in the medium of 9×10⁵ SH-SY5Y cells were assayed by ELISA 24 hours following treatment with 10 µM hippuristanol (+), demonstrating a modest but reproducible decrease in comparison to control cells (−). …”

(A) Latency to the first interictal epileptiform discharge (IED) and (B) Number of IEDs in rats with lateral FPI or sham-operation. by PLOS ONE (2189197)

“…<p>Note a decrease in latency to the 1^st IED (p  =  0.03) and an increase in IEDs (p  =  0.03) in injured rats (n  =  7) as compared to sham-operated animals (n  =  6). …”

Construction of New MRI Contrast Agents for Spatiotemporal Visualization of Nitric Oxide in Ischemia/Reperfusion Organs by Libang Zhang (19803046)

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Abnormal visual experience-induced homeostatic synaptic plasticity in GluR1-S831A mutants. by Anubhuti Goel (225953)

“…<p><b>(A)</b> Left: average mEPSC amplitude decreased with dark-exposure (D) and did not decrease any further with re-exposure to light (L). *: Significantly different from NR (N) at p<0.01, Fisher's PLSD posthoc test. …”

Baseline characteristics of patients according to their CBS. by István Szegedi (11091230)

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Baseline parameters and specific hemostasis markers according to short-term functional outcomes in the studied cohort. by István Szegedi (11091230)

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Baseline parameters and specific hemostasis markers according to long-term functional outcomes in the studied cohort. by István Szegedi (11091230)

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Independent predictors of unfavorable long-term outcome^a (mRS) in the total cohort. by István Szegedi (11091230)

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Independent predictors of poor short-term outcome^a in the studied cohort. by István Szegedi (11091230)

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Occupancy model results using habitat as a covariate that affects occupancy, detection probability, or both (pre-COVID conditions only). by Ishana Shukla (20189612)

Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain by Jiawen Lang (4288540)

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