The expression of Myc leads to a decreased rate of dinitrophenol uncoupled respiration when glutamate+malate and succinate+rotenone were used as complex I and complex II substrates compared to the mitochondria from Myc-OFF or single transgenic mice (Single Tg) (Panel A). by Hyoung-gon Lee (73934)

“…<p>Myc did not affect the oxidation of TMPD-ascorbate (Panel A). Direct measurement of electron transport chain enzyme activity shows that Myc decreased activities of complex I, NCR (NADH cytochrome <i>c</i> oxidoreductase), and complex III (Panel B). …”

Table_1_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.DOCX by Ebru Karasu (5158097)

“…In a mono-centered prospective clinical study with polytraumatized patients, we found significantly increased granulocyte-derived MVs containing the C5a receptor (C5aR1, CD88) on their surface. …”

Image_1_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…In a mono-centered prospective clinical study with polytraumatized patients, we found significantly increased granulocyte-derived MVs containing the C5a receptor (C5aR1, CD88) on their surface. …”

Image_4_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…In a mono-centered prospective clinical study with polytraumatized patients, we found significantly increased granulocyte-derived MVs containing the C5a receptor (C5aR1, CD88) on their surface. …”

Image_2_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…In a mono-centered prospective clinical study with polytraumatized patients, we found significantly increased granulocyte-derived MVs containing the C5a receptor (C5aR1, CD88) on their surface. …”

Image_3_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…In a mono-centered prospective clinical study with polytraumatized patients, we found significantly increased granulocyte-derived MVs containing the C5a receptor (C5aR1, CD88) on their surface. …”

MiR-26a regulates insulin secretion through modulating actin remodeling. by Haixia Xu (479002)

“…RIP TG mice showed an increase of 204 proteins and a decrease of 104 proteins. (D) KEGG pathway analysis on islet proteins deregulated in RIP TG mice. …”

Modelled global climate suitability for <i>Aleurocanthus woglumi</i> under a historical climate scenario, represented by a composite of natural rainfall and irrigation scenarios ba... by Antigoni Akrivou (11858940)

Multiple Receiver Operating Characteristic (ROC) curves as a function of sensitivity vs 1-specificity to compare the performance of markers and combos for (A) Primary Knee Osteoart... by Sakuni Rankothgedera (11457923)

Data_Sheet_1_Expanded Diversity and Phylogeny of mer Genes Broadens Mercury Resistance Paradigms and Reveals an Origin for MerA Among Thermophilic Archaea.ZIP by Christos A. Christakis (10742055)

“…<p>Mercury (Hg) is a highly toxic element due to its high affinity for protein sulfhydryl groups, which upon binding, can destabilize protein structure and decrease enzyme activity. …”

Supplemental Figure 1.LAMP2a Levels were Altered with Pharmacological Agents by Rajeshwary Ghosh (9764078)

“…The corresponding bar graph shows the fold decrease in LAMP2a-positive lysosomes relative to control cells (F) LAMP2a protein levels were detected by immunoblots of isolated lysosomal fractions from cardiomyocytes treated with 10 mM 3-MA or Veh for 24 hours. …”

Obesity Resistance and Enhanced Insulin Sensitivity in <i>Ahnak</i>^-/- Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure by Jae Hoon Shin (438372)

“…AHNAK-KO male mice were fed a high-fat diet (HFD; 60% calories from fat) and examined for glucose and insulin tolerances, for body fat compositions, and by hyperinsulinemic-euglycemic clamping. …”

Jmjd6a regulates <i>GSK3β</i> RNA splicing in <i>Xenopus laevis</i> eye development by Jee Yoon Shin (7067369)

“…We further found down-regulation of gene expression related to eye development such as <i>Rx1</i>, <i>Otx2</i>, and <i>Pax6</i> in <i>Jmjd6a</i> morpholino injected embryos. …”

Peck’s formula for simulating a bilinear settlement curve. by Xingli Jia (13994009)

BSA genetic mapping reveals three QTL for pyflubumide resistance. by Seyedeh Masoumeh Fotoukkiaii (5123303)

“…Dashed red lines delineate statistical significance for QTL detection as assessed by a permutation approach (FDR of 5%). In all panels, chromosomes are ordered by decreasing length and are indicated by alternating shading. …”

A neonatal murine model of coxsackievirus A4 infection for evaluation of vaccines and antiviral drugs by Zhenjie Zhang (530750)

“…<p>Coxsackievirus A4 (CVA4) infection can cause hand, foot and mouth disease (HFMD), an epidemic illness affecting neonatal and paediatric cohorts, which can develop to severe neurological disease with high mortality. …”

Data_Sheet_1_C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection.DOCX by Daria Briukhovetska (9098294)

“…Further, C3 can bind to T. gondii resulting in limited complement activation. Here, we determined the role of C5a/C5aR1 axis activation for the early innate immune response in a mouse model of peritoneal T. gondii infection. …”

Activity of a thermosensory neuron AFD modulates curving rates and circulating direction of locomotion. by Muneki Ikeda (5166362)

Data_Sheet_1_The Salvinorin Analogue, Ethoxymethyl Ether Salvinorin B, Promotes Remyelination in Preclinical Models of Multiple Sclerosis.PDF by Kelly F. Paton (3934061)

“…In the experimental autoimmune encephalomyelitis model, we found that EOM SalB (0.1–0.3 mg/kg) effectively decreased disease severity in a KOR-dependent manner and led to a greater number of animals in recovery compared to U50,488 treatment. …”

Expression of TGFβ1 and RASAL1 by qPCR and Western blotting in GTM cells compared to NTM cells. by Fiona McDonnell (2636635)

“…<p><b>A.</b> mRNA expression of TGFβ1 and RASAL1 by qPCR. …”