K-means++ clustering algorithm. by Zhen Zhao (159931)

“…Firstly, recursive feature elimination using cross validation (RFECV), maximum information coefficient (MIC), and mean decrease accuracy (MDA) methods were utilized to select population distribution feature factors. …”

Mechanism of Peroxynitrite Interaction with Ferric <i>M. tuberculosis</i> Nitrobindin: A Computational Study by Andresa Messias (14384003)

“…Our results indicate that ONOO^– and ONOOH migration is almost unhindered, consistent with the exposed metal center of <i>Mt</i>-Nb(III). To further analyze the ligand binding process, we computed potential energy profiles for the displacement of the Fe(III)-coordinated water molecule using a hybrid QM/MM scheme at the DFT level and a nudged elastic band approach. …”

Mechanism of Peroxynitrite Interaction with Ferric <i>M. tuberculosis</i> Nitrobindin: A Computational Study by Andresa Messias (14384003)

“…Our results indicate that ONOO^– and ONOOH migration is almost unhindered, consistent with the exposed metal center of <i>Mt</i>-Nb(III). To further analyze the ligand binding process, we computed potential energy profiles for the displacement of the Fe(III)-coordinated water molecule using a hybrid QM/MM scheme at the DFT level and a nudged elastic band approach. …”

Validating the stability of the analysis against nonuniform coverage of a fish’s trajectory. by Lear Cohen (15353793)

“…<p>We used three tuning curves of firing rate to position in the vertical axis as recorded from three different fish to simulate firing patterns in a real trajectory (panel A, left panel, black curve), which partially covered the experimental water tank. …”

Downregulation of LGR4 decreases ARPE-19 cell migration. by Qiang Hou (495704)

The variable importance of each histone modification in determining RNA expression levels was obtained by random forest as mean decrease in node impurity. by Yayoi Natsume-Kitatani (211588)

Table_2_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_5_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Image_2_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.tif by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_4_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_3_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Impact of combined induction of XBP1s and ATF6 on mutational tolerance varies across Env structural elements. by Jimin Yoon (9646685)

Subjects:

Inhibition of the mitochondrial fission decreases mtROS production. by Dong Ma (584680)

Inhibition of TMEM16A decreased SW620 cell migration and invasion. by Yujie Sui (549090)

Mean plasma concentration profiles of oseltamivir and oseltamivir carboxylate after a single oral administration of oseltamivir at 75 mg. by Jaeseong Oh (3947381)

Knockdown of AR expression decreases the efficiency of KSHV infection in endothelial cells. by Xing Wang (154377)

“…(g, h) Knockdown of AR and EphA2 expression decreases nuclear LANA expression in SLK cells, as determined by an immunofluorescence assay and quantitative analysis by Image J software. …”

Coupled Dynamics of Droplet Impact on a Flexible, Hydrophilic Cantilever Beam by Bibek Kumar (14082303)

“…We experimentally study the droplet impact on a flexible, hydrophilic cantilever beam. …”

(A) Experimental timeline and (B) behavioural results (mean ± SEM) in Experiment 2 on the effect of adaptation to a decrease and to an increase in height of the ball drop. by Ana Tajadura-Jiménez (315994)

PI3K activity is required for induction of cerebellar LTP. by Claire Jackson (362873)

P-Rex-deficient Purkinje neurons have normal passive membrane properties and basal synaptic transmission. by Claire Jackson (362873)