Downstream signaling pathways of the Htr2b receptor in the mammary gland are altered by serotonin deficiency. by Jimena Laporta (383836)

Homozygous deletion of the orthologous murine <i>Ikzf1</i> enhancer results in significantly decreased <i>Ikzf1</i> expression, increased cell proliferation, and altered B cell dif... by Vincent U. Gant (9955199)

c-Src mediates the effect of AngII on LPL expression in SAT. by Tsuyoshi Uchiyama (201495)

An enriched environment prevents diabetes-induced cognitive impairment in rats by enhancing exosomal miR-146a secretion from endogenous bone marrow-derived mesenchymal stem cells by Kenta Kubota (5778341)

“…BM-MSCs isolated from STZ/CC rats had functional and morphological abnormalities that were not detected in STZ/EE BM-MSCs. The miR-146a levels in exosomes in conditioned medium of cultured BM-MSCs and serum from STZ/CC rats were decreased compared with non-diabetic rats, and the level was restored in STZ/EE rats. …”

Spatially Resolved Dissolution and Speciation Changes of ZnO Nanorods during Short-Term <i>in Situ</i> Incubation in a Simulated Wastewater Environment by Miguel A. Gomez-Gonzalez (7410050)

“…Complementary <i>ex situ</i> X-ray absorption spectroscopy and scanning electron microscopy confirmed a significant decrease in the ZnO contribution over time. …”

Discovery of PiragliatinFirst Glucokinase Activator Studied in Type 2 Diabetic Patients by Ramakanth Sarabu (1971181)

“…Compound <b>1</b>, a glucokinase activator (GKA) lead that we have previously disclosed, caused reversible hepatic lipidosis in repeat-dose toxicology studies. …”

PKCβ1 and p38 MAP kinase activation by AngII in VAT and SAT, respectively. by Tsuyoshi Uchiyama (201495)

Preconditioned medium from hypoxic human cardiac fibroblasts affected cardiomyocyte beating frequency. by Mikael Sandstedt (3072450)

Analysis of types of AngII receptors and G proteins involved in AngII regulation of LPL expression. by Tsuyoshi Uchiyama (201495)

The Catalytic Subunit of the System L1 Amino Acid Transporter (<i>Slc7a5</i>) Facilitates Nutrient Signalling in Mouse Skeletal Muscle by Nadège Poncet (527942)

“…We generated a floxed <i>Slc7a5</i> mouse strain which, when crossed with mice expressing Cre driven by a global promoter, produced <i>Slc7a5</i> heterozygous knockout (<i>Slc7a5</i>+/−) animals with no overt phenotype, although homozygous global knockout of <i>Slc7a5</i> was embryonically lethal. …”

Transient over-expression of hMp84 impairs cell proliferation and stimulates cell death in HT-144 melanoma cells. by Daniele Moretti (379766)

PLCβ4 is critical for the inhibition of LPL expression in visceral adipocytes. by Tsuyoshi Uchiyama (201495)

Image_1.TIF by Lu Liu (171341)

“…Furthermore, we demonstrate that Ac2-26 induces IKKβ accumulation in lysosomes and that lysosomal-associated membrane protein 2A (LAMP-2A), not LC-3, is enhanced in microglia exposed to Ac2-26. …”

Eutrophication and predator presence overrule the effects of temperature on mosquito survival and development by Maarten Schrama (2924811)

“…We carried out two mesocosm experiments with the common brown house mosquito, <i>Culex pipiens</i>, a confirmed vector for West Nile Virus, Usutu and Sindbis, and a controphic species; the harlequin fly, <i>Chironomus riparius</i>. …”

Image_1_Programmed Cell Senescence in the Mouse Developing Spinal Cord and Notochord.TIF by Jorge Antolio Domínguez-Bautista (10033274)

“…Expression of p21^CIP1/WAF was documented in epithelial cells of the spinal cord and the notochord, while p16^INK4A was observed in motoneurons. Treatment with the senolytic ABT-263 decreased the number of motoneurons, supporting their senescent phenotype. …”

Image_3_Programmed Cell Senescence in the Mouse Developing Spinal Cord and Notochord.TIF by Jorge Antolio Domínguez-Bautista (10033274)

“…Expression of p21^CIP1/WAF was documented in epithelial cells of the spinal cord and the notochord, while p16^INK4A was observed in motoneurons. Treatment with the senolytic ABT-263 decreased the number of motoneurons, supporting their senescent phenotype. …”

Image_2_Programmed Cell Senescence in the Mouse Developing Spinal Cord and Notochord.TIF by Jorge Antolio Domínguez-Bautista (10033274)

“…Expression of p21^CIP1/WAF was documented in epithelial cells of the spinal cord and the notochord, while p16^INK4A was observed in motoneurons. Treatment with the senolytic ABT-263 decreased the number of motoneurons, supporting their senescent phenotype. …”

Decreased CD4⁺ cell cytokine production, macrophage phagocytosis and bacterial clearance in CLP-induced Atg7^f/fCD4-Cre mice. by Chih-Wen Lin (599080)

Transfluthrin elicits spatial repellency in <i>Ae</i>. <i>aegypti</i>. by Felipe Andreazza (11098928)

Decrease of <i>cwp1</i>, <i>cwp2</i>, and <i>myb2</i> gene expression by MLF knock down during vegetative growth using strategy 3. by Zi-Qi Lin (6444350)

“…Fold change is calculated as the ratio of the difference between Cas9MLFko cell line and the control cell line, to which a value of 1 was assigned. Results are expressed as mean ± SD. …”