UPR gene and protein expression of autoimmune hepatitis (AIH) livers compared to pediatric normal controls (pNormal) and pediatric cholestatic liver disease (pCLD) samples. by Alyssa Kriegermeier (4707226)

“…<p>A) Using qPCR, we determine that: compared to AIH livers (n = 5), pCLD livers (n = 10) had decreased expression of IRE1α, XBP1s, and EDEM1 by 78%, 77%, and 67% while ERdj4 gene expression was similar. …”

Total number of indoor mosquitoes vectors collected per household (mean of three occasions) by selected house quality indicators. by Jenny X. Liu (464011)

“…<p>There does not appear to be a consistent or gradient relationship between house quality and the mean mosquito numbers across urban and rural areas. …”

DataSheet1_Examining the paradoxical effects of kratom: a narrative inquiry.PDF by Kirsten E. Smith (10716529)

“…Five of the 10 participants met DSM-5-based criteria for kratom-use disorder (3 mild, 1 moderate, 1 severe, by symptoms counts). When kratom was inadvertently taken in larger than intended doses, participants described a constellation of symptoms that they called “the wobbles” (a jittery feeling accompanied by what seemed to be nystagmus); this was rare, but could be of scientific and clinical interest as a possible manifestation of serotonin syndrome. …”

Anti-CD25 treatment depletes Foxp3^GFP Treg cells and induces decreased fungal loads in Foxp3^GFP C57BL/6 mice. by Maíra Felonato (296591)

Astilbin treatment decreases the percentage of CD44^hiCD62L^lo activated CD4⁺ T cells and several cytokine mRNA expression. by Lele Guo (720961)

Circulating CD161⁺CD4⁺ and CD161^hiCD8⁺ T cells are decreased in allo-SCT patients who develop GVHD. by Anniek B. van der Waart (115983)

Increment of mean [Ca²⁺]_i after addition of septic serum from mice. by Mara R. N. Celes (435880)

“…<p>Cardiomyocytes exposed to serum from septic mice for 2 minutes (upper panel) presented a marked increment of mean [Ca²⁺]_i, around 49%, due to a rise of diastolic ion levels, with decreased amplitude of the calcium transients as compared to cardiomyocytes incubated with serum from sham-operated mice. …”

Enzymes of the ubiquitin system affect A53T α-synuclein aggregation. by Charlotte Vajhøj (11864270)

“…(D) Electrochemiluminescence immunoassay showed down-regulation of α-synuclein protein levels in doxycycline treated neurons in response to SCNA and USP9X siRNAs. Data are shown as mean±SEM. Data in (A) and (B) were analyzed by one-way ANOVA followed by Dunnett’s multiple comparison test (n = 2, m = 2). …”

Reach duration (top) and engagement duration (bottom) difference for all experimental groups (no music-music); mean and standard errors. by Lori-Ann R. Sacrey (370746)

Table 1_Dynamic retinal vessel analysis: flickering a light into the brain.docx by Anna Peterfi (16748403)

“…</p>Results<p>We identified 11 studies, of which most employed a cross-sectional design (91%). …”

Autocorrelation function, variance of the firing rates and timescale of the network activity with external noise predicted by dynamical mean field theory. by Manuel Beiran (6495338)

Snapshotting the Excited-State Planarization of Chemically Locked <i>N</i>,<i>N</i>′‑Disubstituted Dihydrodibenzo[<i>a</i>,<i>c</i>]phenazines by Wei Chen (23863)

“…For deeper understanding of the coupling of electronic processes with conformational motions, we exploit a tailored strategy to harness the excited-state planarization of <i>N</i>,<i>N</i>′-disubstituted dihydrodibenzo­[<i>a</i>,<i>c</i>]­phenazines by halting the structural evolution via a macrocyclization process. …”

Snapshotting the Excited-State Planarization of Chemically Locked <i>N</i>,<i>N</i>′‑Disubstituted Dihydrodibenzo[<i>a</i>,<i>c</i>]phenazines by Wei Chen (23863)

“…For deeper understanding of the coupling of electronic processes with conformational motions, we exploit a tailored strategy to harness the excited-state planarization of <i>N</i>,<i>N</i>′-disubstituted dihydrodibenzo­[<i>a</i>,<i>c</i>]­phenazines by halting the structural evolution via a macrocyclization process. …”

Snapshotting the Excited-State Planarization of Chemically Locked <i>N</i>,<i>N</i>′‑Disubstituted Dihydrodibenzo[<i>a</i>,<i>c</i>]phenazines by Wei Chen (23863)

“…For deeper understanding of the coupling of electronic processes with conformational motions, we exploit a tailored strategy to harness the excited-state planarization of <i>N</i>,<i>N</i>′-disubstituted dihydrodibenzo­[<i>a</i>,<i>c</i>]­phenazines by halting the structural evolution via a macrocyclization process. …”

Snapshotting the Excited-State Planarization of Chemically Locked <i>N</i>,<i>N</i>′‑Disubstituted Dihydrodibenzo[<i>a</i>,<i>c</i>]phenazines by Wei Chen (23863)

“…For deeper understanding of the coupling of electronic processes with conformational motions, we exploit a tailored strategy to harness the excited-state planarization of <i>N</i>,<i>N</i>′-disubstituted dihydrodibenzo­[<i>a</i>,<i>c</i>]­phenazines by halting the structural evolution via a macrocyclization process. …”

Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A by Fiona Fernandes (251389)

“…Additionally, we demonstrated a novel CsA-sensitive interaction between NS5A and both cyclophilin A and B. …”

Image_4_STXBP1 Syndrome Is Characterized by Inhibition-Dominated Dynamics of Resting-State EEG.TIF by Simon J. Houtman (8716335)

“…Brain-wide abnormalities were observed in each of the four resting-state measures assessed here: (i) slowing of activity and increased low-frequency power in the range 1.75–4.63 Hz, (ii) increased long-range temporal correlations in the 11–18 Hz range, (iii) a decrease of our recently introduced measure of functional E/I ratio in a similar frequency range (12–24 Hz), and (iv) a larger exponent of the 1/f-like aperiodic component of the power spectrum. …”

Image_6_STXBP1 Syndrome Is Characterized by Inhibition-Dominated Dynamics of Resting-State EEG.TIF by Simon J. Houtman (8716335)

“…Brain-wide abnormalities were observed in each of the four resting-state measures assessed here: (i) slowing of activity and increased low-frequency power in the range 1.75–4.63 Hz, (ii) increased long-range temporal correlations in the 11–18 Hz range, (iii) a decrease of our recently introduced measure of functional E/I ratio in a similar frequency range (12–24 Hz), and (iv) a larger exponent of the 1/f-like aperiodic component of the power spectrum. …”

Image_3_STXBP1 Syndrome Is Characterized by Inhibition-Dominated Dynamics of Resting-State EEG.TIF by Simon J. Houtman (8716335)

“…Brain-wide abnormalities were observed in each of the four resting-state measures assessed here: (i) slowing of activity and increased low-frequency power in the range 1.75–4.63 Hz, (ii) increased long-range temporal correlations in the 11–18 Hz range, (iii) a decrease of our recently introduced measure of functional E/I ratio in a similar frequency range (12–24 Hz), and (iv) a larger exponent of the 1/f-like aperiodic component of the power spectrum. …”

Image_2_STXBP1 Syndrome Is Characterized by Inhibition-Dominated Dynamics of Resting-State EEG.TIF by Simon J. Houtman (8716335)

“…Brain-wide abnormalities were observed in each of the four resting-state measures assessed here: (i) slowing of activity and increased low-frequency power in the range 1.75–4.63 Hz, (ii) increased long-range temporal correlations in the 11–18 Hz range, (iii) a decrease of our recently introduced measure of functional E/I ratio in a similar frequency range (12–24 Hz), and (iv) a larger exponent of the 1/f-like aperiodic component of the power spectrum. …”