Conformer Distribution in (<i>cis</i>-1,4-DACH)bis(guanosine-5′-phosphate)platinum(II) Adducts: A Reliable Model for DNA Adducts of Antitumoral Cisplatin by Rosa Ranaldo (2444953)

“…In [PtCl₂(<i>cis</i>-1,4-DACH)] (DACH = diaminocyclohexane), the N−Pt−N bite angle (≥97°, as determined by X-ray diffraction analysis) is much larger than those found in other Pt complexes with bidentate diamines or in cisplatin (~91°). …”

Neutrophil depletion is associated with decreased intracellular cytokine levels and changes in transcription factor mRNA expression related to T helper subsets during the chronic s... by Juan David Puerta-Arias (3187089)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibi... by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibi... by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibi... by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibi... by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibi... by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibi... by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibi... by Jinxin Che (791250)

Dietary or gavaged TU-100 and the ginger component decrease enteropooling stimulated by anti-CD3 antibody treatment in specified pathogen free (SPF) and germ free (GF) C57Bl6 mice. by Nobuhiro Ueno (346397)

Id2 down regulation drives Neuro2a AD cells towards the AI phenotype. by Lina Chakrabarti (501389)

“…<p>(<b>A, B</b>) BrdU incorporation assay demonstrated that transfection of AD cells with Id2-siRNA reduced the rate of proliferation. …”

Knockdown of CN-A attenuate the protein synthesis inhibition under ER stress. by Mariana Bollo (244365)

“…Note that CN is decreased by the CN-A morpholinos treatment only after ER stress (lane M-tg 6). …”

LTP modulates steady-state inactivation of A-type K⁺ currents. by Sung-Cherl Jung (261358)

“…Scale bars, 200 pA, 50 ms. The A-current available for activation at −60 mV was significantly decreased only in the neurons receiving paired stimulation 10 min after conditioning stimulation (a red arrow). …”

The coefficients of the stiffness model according to condition levels of anchor points and a trend line of the coefficients. by Jihun Kim (10091)

Tumor vessel activity is inhibited by 6a-P peptide. by Tong-Young Lee (250877)

“…Immunohistochemistry result shows that VEGF/KDR complexes are colocalized with vessels (VWF staining) on PBS treated tumor (A; up panel). However, the staining signal is decreased after peptide treatment (A; lower panel). …”

Expression of proteins associated with AD is altered by eIF4A inhibition. by Andrew Bottley (361376)

“…Significant differences (p≤0.05 by t-test) are indicated by asterisks. <b>C</b>. Secreted A-beta levels in the medium of 9×10⁵ SH-SY5Y cells were assayed by ELISA 24 hours following treatment with 10 µM hippuristanol (+), demonstrating a modest but reproducible decrease in comparison to control cells (−). …”

Time of thrombin in free and bound states within AA, AP, and wild-type junctions. by Michael A. Kelley (13804062)

Clinical significance of <i>STM</i>_<i>FCS</i>. by Peter A. Pahapill (8468607)

Blockade of PKCγ and PKC/Mζ with isozyme-specific pseudosubstrate inhibitors abolishes prenatal cocaine exposure induced increase and decrease in synaptic membrane associated GRASP... by Kalindi Bakshi (343243)

A white matter voxel’s importance for a given eigenmode is defined as the decrease in the corresponding eigenvalue when a 12mm-diameter lesion is placed at that voxel, damaging enc... by Maxwell B. Wang (4166806)

“…The brighter the voxel, the larger the corresponding decrease in eigenvalue. The <i>X</i> and <i>Z</i> coordinates of each taken axial and sagittal plane are shown for reference: increasing <i>X</i> denotes the sagittal plane moving from the right to left side of the brain, while increasing <i>Z</i> denote inferior to superior axial planes.…”