Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations by Igor Shamovsky (1845193)

“…Results suggest that bioactivation of ArNH₂ follows the anionic pathway. We demonstrate that H-bonding and/or geometric fit of ArNH₂ to CYP1A2 as well as feasibility of both proton abstraction by the ferriheme-peroxo base and heterolytic cleavage of arylhydroxylamines render molecules mutagenic. …”

Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations by Igor Shamovsky (1845193)

“…Results suggest that bioactivation of ArNH₂ follows the anionic pathway. We demonstrate that H-bonding and/or geometric fit of ArNH₂ to CYP1A2 as well as feasibility of both proton abstraction by the ferriheme-peroxo base and heterolytic cleavage of arylhydroxylamines render molecules mutagenic. …”

Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations by Igor Shamovsky (1845193)

“…Results suggest that bioactivation of ArNH₂ follows the anionic pathway. We demonstrate that H-bonding and/or geometric fit of ArNH₂ to CYP1A2 as well as feasibility of both proton abstraction by the ferriheme-peroxo base and heterolytic cleavage of arylhydroxylamines render molecules mutagenic. …”

The percentage of persons by household telephone status and percentage of persons tested for HIV by telephone status, NHIS, United States, 2003–2013^a. by Michelle M. Van Handel (732792)

EVs obtained from U937 cells increased the expression of adhesion molecules in endothelial cells EA.hy926. by Myriam Lucia Velandia-Romero (8259726)

OSR model describes data from HepG2 cells exposed to DEM when NRF2 stimulates KEAP1 production. by Elsje J. Burgers (20903422)

We compared the Fugl-Meyer (FMA) clinical assessment scores for individuals with stroke with their performance for each outcome measure. by Devin Sean Austin (20285144)

“…We found that individuals with stroke with more severe levels of hemiparesis had decreased performance in Peak Speed (A), Average Speed (B), Error Time (C), Movement Time (D), and Number of Speed Peaks (E) when compared to both mild and control groups (***p < 0.001).…”

Processive receptor methylation compromises adaptation and decreases signaling noise. by William Pontius (460803)

“…Fluctuations are largest in <b>M1</b> and smallest in model <b>M2</b>.…”

Is there any relation between anthropometric indices and decrease in seminal parameters? by Juliana Christofolini (6851441)

Presentation_1_Do We Overestimate the Within-Variability? The Impact of Measurement Error on Intraclass Coefficient Estimation.pdf by Rafael Wilms (8858795)

“…Our contribution firstly shows via mathematical proof that measurement error increases the within-variance, which in turn decreases the ICC(1). Further, we provide a numerical example, and examine the RMSEs, alpha error rates and the inclusion of zero in the confidence intervals for ICC(1) estimation with and without measurement error. …”

Table_1_Biomarkers Associated With Aortic Valve Calcification: Should We Focus on Sex Specific Processes?.DOCX by Frederique E. C. M. Peeters (9108308)

“…Mechanisms are rapidly elucidated and sex differences are suggested to be involved. Therefore, we sought to identify biomarkers involved in aortic valve calcification (AVC) stratified by sex.…”

C E Ferulic decreases tumor number in female mice. by Erin M. Burns (412412)

“…<p>Tumors with a diameter larger than 1 mm were measured weekly with calipers. …”

Adenosine inhibits AMPA EPSCs by decreasing presynaptic glutamate release. by Shouping Wang (402959)

Symptoms, laboratory findings, and clinical syndromes of infants with SARS-CoV-2 infection. by Pierre-Philippe Piché-Renaud (10052970)

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Logistic regression analysis of infants’ characteristics associated with COVID-19 hospital admission. by Pierre-Philippe Piché-Renaud (10052970)

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Characteristics of infants with SARS-CoV-2 infection in Canada. by Pierre-Philippe Piché-Renaud (10052970)

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Flow chart of cases reported to the CPSP COVID-19 study until May 31, 2021. by Pierre-Philippe Piché-Renaud (10052970)

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Odds ratios of COVID-19 admission by continuous infant age, compared to infants at 100 days of age. by Pierre-Philippe Piché-Renaud (10052970)

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Fig 2 - by Pierre-Philippe Piché-Renaud (10052970)

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Human Multipotent Stromal Cells (MSCs) Increase Neurogenesis and Decrease Atrophy of the Striatum in a Transgenic Mouse Model for Huntington's Disease by Brooke R. Snyder (253093)

“…</p><h3>Results</h3><p>We implanted hMSCs into the striatum of transgenic mice (N171-82Q) that are a model for HD. …”