<i>tsn</i> mutations cause spermatogenic cell overproliferation, cytokinetic defects during meiosis, fewer spermatid bundles, and reduced male fertility. by Hsueh-Yen Ku (848090)

“…Asterisks indicate the hubs. The <i>tsn</i> mutant testis had more pH3-positive spermatogonia and was larger in size. …”

Feasibility and clinical impact of routine molecular testing of gastrointestinal cancers at a tertiary centre with a multi-gene, tumor-agnostic, next generation sequencing panel by Giacomo Bregni (9281195)

“…<p> High-throughput sequencing technologies are increasingly used in research but limited data are available on the feasibility and value of these when routinely adopted in clinical practice.</p> <p> We analyzed all consecutive cancer patients for whom genomic testing by a 48-gene next-generation sequencing (NGS) panel (Truseq Amplicon Cancer Panel, Illumina) was requested as part of standard care in one of the largest Belgian cancer networks between 2014 and 2019. …”

The impact of a breast cancer diagnosis on health-related quality of life. A prospective comparison among middle-aged to elderly women with and without breast cancer by Randi V. Karlsen (2545756)

“…</p> <p><b>Results</b> Women with breast cancer reported significantly larger decreases in HQoL from before to after diagnosis than those who remained breast cancer-free (physical component summary, −2.0; 95% CI −2.8; −1.2, mental component summary, −1.5, 95% CI −2.3; −0.6). …”

Identity in Family Firms: A Theoretical Analysis of Incentives and Contracts by Marcelo Sanches Pagliarussi (10413760)

“…<div><p>Abstract We developed a principal-agent model that coherently and parsimoniously explains previous findings from research on executive compensation in family firms. …”

Nutritional stress targets LeishIF4E-3 to storage granules that contain RNA and ribosome components in <i>Leishmania</i> by Rohit Shrivastava (6459608)

“…We hypothesize that each is responsible for a different function during the life cycle. …”

A <i>Clostridium difficile</i> Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence by Michele Chu (731561)

“…<i>difficile</i> infection is unknown. We explored the contribution of a conserved CWG locus to <i>C</i>. …”

DataSheet1_Efficacy of a paper-based interleukin-6 test strip combined with a spectrum-based optical reader for sequential monitoring and early recognition of respiratory failure i... by Cheng-Han Chen (15414512)

“…Respiratory failure was associated with a higher mortality rate (p = 0.015). Decreased serum IL-6 concentration within 24 h after admission indicated a lower risk of developing respiratory failure in the later admission course (Receiver Operating Characteristic [ROC] curve = 0.696).…”

DataSheet1_Efficacy of a paper-based interleukin-6 test strip combined with a spectrum-based optical reader for sequential monitoring and early recognition of respiratory failure i... by Cheng-Han Chen (15414512)

“…Respiratory failure was associated with a higher mortality rate (p = 0.015). Decreased serum IL-6 concentration within 24 h after admission indicated a lower risk of developing respiratory failure in the later admission course (Receiver Operating Characteristic [ROC] curve = 0.696).…”

A Device for Performing Automated Balloon Catheter Inflation Ischemia Studies by Silas J. Leavesley (555725)

“…This system has significantly increased the reproducibility of coronary collateral growth studies in our laboratory, resulting in a significant decrease in the numbers of animals needed to complete each study while relieving laboratory personnel from the burden of extra working hours and enabling us to continue studies over periods when we previously could not. …”

Table_1_Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet.xlsx by Ana Ramos-Levi (724988)

“…</p>Conclusions<p>We identify a core set of SNPs in their association with diabetes and GDM in a large cohort of patients from two main ethnicities from a single center. …”

Table_2_Kynurenic acid as a biochemical factor underlying the association between Western-style diet and depression: A cross-sectional study.docx by Heather M. Francis (3665893)

“…Mixed-effects regression analysis showed the glutamatergic inhibitor, KA, was the only biomarker to have a significant association with depression symptoms in a model adjusted for demographic and lifestyle variables: a unit increase in KA was associated with 0.21 unit decrease in Depression Anxiety and Stress Scale-21 depression score (p = 0.009). …”

Table_1_Kynurenic acid as a biochemical factor underlying the association between Western-style diet and depression: A cross-sectional study.docx by Heather M. Francis (3665893)

“…Mixed-effects regression analysis showed the glutamatergic inhibitor, KA, was the only biomarker to have a significant association with depression symptoms in a model adjusted for demographic and lifestyle variables: a unit increase in KA was associated with 0.21 unit decrease in Depression Anxiety and Stress Scale-21 depression score (p = 0.009). …”

Image_1_Kynurenic acid as a biochemical factor underlying the association between Western-style diet and depression: A cross-sectional study.jpg by Heather M. Francis (3665893)

“…Mixed-effects regression analysis showed the glutamatergic inhibitor, KA, was the only biomarker to have a significant association with depression symptoms in a model adjusted for demographic and lifestyle variables: a unit increase in KA was associated with 0.21 unit decrease in Depression Anxiety and Stress Scale-21 depression score (p = 0.009). …”

Table_3_Kynurenic acid as a biochemical factor underlying the association between Western-style diet and depression: A cross-sectional study.docx by Heather M. Francis (3665893)

“…Mixed-effects regression analysis showed the glutamatergic inhibitor, KA, was the only biomarker to have a significant association with depression symptoms in a model adjusted for demographic and lifestyle variables: a unit increase in KA was associated with 0.21 unit decrease in Depression Anxiety and Stress Scale-21 depression score (p = 0.009). …”

Table_4_Kynurenic acid as a biochemical factor underlying the association between Western-style diet and depression: A cross-sectional study.docx by Heather M. Francis (3665893)

“…Mixed-effects regression analysis showed the glutamatergic inhibitor, KA, was the only biomarker to have a significant association with depression symptoms in a model adjusted for demographic and lifestyle variables: a unit increase in KA was associated with 0.21 unit decrease in Depression Anxiety and Stress Scale-21 depression score (p = 0.009). …”

Nanoparticle Surfactants as a Route to Bicontinuous Block Copolymer Morphologies by Bumjoon J. Kim (1477771)

“…The surface chemistry of nanoparticles can be modified so that these particles behave like surfactants and localize at interfaces between two fluids. We demonstrate that small volume fractions φ_P of such surfactant nanoparticles added to lamellar diblock copolymers lead initially to a decrease in lamellar thickness with φ_P, a consequence of decreasing interfacial tension, up to a critical value of φ_P, beyond which the block copolymer adopts a bicontinuous morphology. …”

Packing and Sorting Colloids at the Contact Line of a Drying Drop by Cécile Monteux (1687471)

“…In this article, we study the drying kinetics of a sessile droplet containing latex particles. …”

Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of <i>MAN2C1</i> and Children's Intelligence by Alejandro Cáceres (3162900)

“…Although the haplotype-genotypes have been most likely generated by decreased or absent recombination among them, we could not confirm that they were the product of inversion polymorphisms in the region. …”

A Genome-Wide mRNA Screen and Functional Analysis Reveal <i>FOXO3</i> as a Candidate Gene for Chicken Growth by Biao Chen (795331)

“…A total of 60, 23, 153 and 359 differentially expressed genes were detected in WRR_h vs. …”

Estimating Metabolic Fluxes Using a Maximum Network Flexibility Paradigm by Wout Megchelenbrink (523390)

“…By mapping measured flux data from central metabolism to the genome-scale models of <i>Escherichia coli</i> and <i>Saccharomyces cerevisiae</i> we show that i) indeed, most of the measured fluxes agree with a high adaptability of the network, ii) this result can be used to further reduce the space of feasible solutions iii) this reduced space improves the quantitative predictions made by FBA and contains a significantly larger fraction of the measured fluxes compared to the flux space that was reduced by a uniform sampling approach and iv) MMF can be used to select reactions in the network that contribute most to the steady-state flux space. …”