Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2. by Thirumal Kumar, D

“…The D-2-HGA includes two subtypes: type I and type II caused by the mutations in D2HGDH and IDH2 proteins, respectively. In this study, we studied six mutations, four in the D2HGDH (I147S, D375Y, N439D, and V444A) and two in the IDH2 proteins (R140G, R140Q). …”
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EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS by ABU-EL-RUZ, RASHA

“…Background: Chlamydia trachomatis (CT) is a Sexually Transmitted Disease (STD); it leads to health complications and infertility if not treated. …”
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Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response by Xue, Mingzhan

“…Pharmacological decrease of MG with Glo1 inducer, trans-resveratrol and hesperetin in combination, offers a novel treatment strategy to counter UPR-related cell dysfunction, particularly in hyperglycemia associated with diabetes.…”
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The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets by Cenciarelli, Carlo

“…In the last decade Stat3 has gained attention as therapeutic target in cancer but there is not yet any approved Stat3-based glioma therapy. Herein, we report that exposure to a Stat3/5 inhibitor, induced apoptosis either in shHes1-CSC or control cells. …”
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Effect of hyperglycemia on EPCs function and regenerative ability by Hendawi, Hadeel Khalil

“…This research aims to test the EPC subtype blood outgrowth endothelial cells (BOECs) and their ability to survive and function under chronic hyperglycemic conditions. For that, we studied BOECs viability, response to shear stress, angiogenesis ability, and barrier function under normoglycemic (5.5mM) and hyperglycemic (25mM) conditions. …”
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Roadmap toward energy-positive upfront nitrogen removal process in baseload LNG plant by Mkacher, Hajer

“…The results show that UNrem of 87.5% from the NG feed can reduce the total power requirements by 0.24%, increase the production flow rate by 4.4%, and decrease the exergy losses by 0.23% compared with the base case. …”
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Improvement of both lipid and biomass productivities of Qatar Chlorocystis isolate for biodiesel production and food security by Saadaoui, Imen

“…Most previous research evidenced that the increase of the lipid content is accompanied by a decrease of the biomass production, which increases the cost of the downstream processing. …”
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Superior photocatalytic activity of Cu doped NiWO4 for efficient degradation of benzene in air even under visible radiation by Tri N.L.M.

“…This was because Cu effectively acted as novel dopant, which not only affected valence band (VB) top and conduction band (CB) bottom of NiWO4 but also formed a medium energy level between CB and VB of the NiWO4 to decrease its energy band gap and electron-hole recombination rate. …”
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Modeling of dual-metal Schottky contacts based silicon micro and nano wire solar cells by Rabbani, M. Golam

“…However current per surface area exposed to light is found to decrease rapidly with increase in length. The use of a multi-contact interdigitated design for long wires is investigated to increase the photovoltaic response of the devices.…”
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Corporate governance and cost of debt financing: Empirical evidence from Canada by Ghouma, Hatem

“…Our empirical findings point to a decrease in the bond spreads for an improvement of the overall quality of the corporate governance index. …”
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Trends in prevalence of depression and anxiety symptoms and effects of sociodemographic variables before and after the first wave of COVID-19 in Qatar by Khaled, Salma M.

“…The data for 2020/21 showed a 35.1% and 29.2% decrease in depression and anxiety symptoms scores compared to pre-pandemic years (2017/2018) after adjusting for sociodemographic factors. …”
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Effect of outdoor temperature on the power-conversion efficiency of newly synthesized organic photosensitizer based dye-sensitized solar cells by Mehmood U.

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Integrated planning of spare parts and service engineers with partial backlogging by Rahimi-Ghahroodi, S.

“…In a numerical study, we show that for problems with more than five types of spare parts it is preferable to use approximate evaluations as they become significantly faster than exact evaluation. …”
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Antibiotic Prescription Patterns for Upper Respiratory Tract Infections in Outpatient Qatari Population in the Private Sector by Butt, Adeel Ajwad

“…Results: There were a total of 75,733 claims during the study period. …”
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Evacuated tube heat pipe solar collector for Encontech engine-driven reverse osmosis solar desalination by Takalkar, Gorakshnath

“…Both energetic and exergetic efficiencies exhibit upper values at A co/A abs ratio up to 1. Further increment in this ratio up to 3 resulted in a decrease in the efficiency of the ETHPSC.…”
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Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis by Manresa M.C.

“…Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. …”
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Effect of mobile text messages on antiretroviral medication adherence and patient retention in early HIV care: An open-label, randomized, single center study in south Florida by Sherman, Elizabeth M.

“…Background People with HIV (PHIV) with limited access to health services often experience suboptimal antiretroviral therapy (ART) adherence. We investigated whether a daily text messaging intervention improves ART adherence and retention in early HIV care in PHIV in a south Florida hospital-based clinic. …”
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Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications by Souayeh, Basma

“…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …”
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Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. by Wang, Yue

“…Egg consumption at each survey was assessed by a 3-d 24-h recall and weighed food record methods. …”
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Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes by Patel, J. P.

“…Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. …”
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