Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Diabetic Sensorimotor Polyneuropathy Severity Classification Using Adaptive Neuro Fuzzy Inference System by Haque, Fahmida

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Semi-continuous anaerobic digestion of the organic fraction of municipal solid waste: digester performance and microbial population dynamics by Najoua, Mlaik

“…Three organic loading rates (OLRs) were tested throughout the anaerobic process (1.36, 2.5 and 3.5 g VS/L.d). The achieved results showed that biogas yield decreased with the increase of OLR. …”
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Thermal properties of phase-change materials based on high-density polyethylene filled with micro-encapsulated paraffin wax for thermal energy storage by Karkri, M.

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Experimental results and modelling of corrosion-damaged concrete beams strengthened with externally-bonded composites by Elghazy M.

“…This paper presents the results of 3D finite element (FE) modelling of corrosion-damaged reinforced concrete (RC) beams strengthened in flexure with externally-bonded composites. …”
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Wireless Car Control Over the Cellular System by Al-Shamali, Haleema Khamis

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Plasticization and co-crystallization in LLDPE/wax blends. by Gumede, Thandi P.

“…Upon cooling from the melt, two crystalline phases develop for blends with more than 10 wt % wax characterized by widely different melting points. …”
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TRAINING PRACTICES OF FILIPINO ATHLETES DURING THE EARLY COVID-19 LOCKDOWN by Pagaduan, J.C.

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Effects of financial turmoil on financial integration and risk premia in emerging markets by Boubakri, Salem

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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions by Salih, Isam M.

“…Plots of In (AA) versus time where A and A are absorbance values of the Cu(III) product at time t and infinity, respectively, showed marked deviations from linearity. …”
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Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac by Abdulilah Dawoud, Bani-Yaseen

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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…The lifetime probability of HIV acquisition remains highest in the sub-Saharan Africa super-region, where it declined from its 1995 peak of 21·8% (20·1–24·2) to 8·7% (7·5–10·7) in 2021. Four of the seven GBD super-regions had a lifetime probability of less than 1% in 2021. …”
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Baseline monitoring gastropods in the intertidal zone of Qatar - target species and bioindicators for hyper-thermic and hyper-saline Conditions by Al-Maslamani, Ibrahim

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Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells by AlDisi, Sara

“…Cardiovascular diseases (CVDs) are still the number one cause of morbidity and mortality both in Qatar and worldwide. A major risk factor of CVDs is atherosclerosis, the hardening of blood vessels caused by decreased diameter and formation of plaque. …”
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Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties by Slimani, Ahmed

“…The XRD results show that the 850 °C is the best calcination temperature, where the NBT-6BT ceramic had the largest crystallite size with a dense sample, 96% of the theoretical value. However, the density decreased significantly with increasing the calcination temperature above 850 °C due to the secondary phase formation. …”
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Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method by Gao P.

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Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Traumatic Brain Injury? by Al-Haj, Nadine

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Computational modeling of motile cilia generated cerebral flow dynamics in zebrafish embryo by Salman, Huseyin Enes

“…Methods: The dynamics of motile-cilia driven flow is analyzed employing computational fluid dynamics (CFD) modeling. A 2D model is generated using the time-lapse microscopic movies showing movements of a fluorescently labeled motile-cilia in a zebrafish embryo (48-hour post-fertilization). …”
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Reducing energy consumption of CO2 desorption in CO2-loaded aqueous amine solution using Al2O3/HZSM-5 bifunctional catalysts by Zhang X.

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Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. by Seidel, Monika

“…Deletion of the β8-β9 sequence produces unstable tetrameric channels with subdued intracellular Ca2+ mobilization implicating a role for this domain in channel opening. The arrhythmia-linked R176Q mutation within the β8-β9 loop decreases N-terminus tetramerization but does not affect RyR2 subunit tetramerization or the N-terminus interaction with C-terminus. …”
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