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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…Our predictions revealed that E17K, R67W, V164G, E319G, R391G, D32Y, L52H, L52R, and W80R were the most pathogenic mutations. …”
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Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit
Published 2024“…Gentamicin dose regimen continuations, dose regimen decreases and dose regimen discontinuations were inappropriately applied in 27% (n = 10), 25% (n = 2) and 14% (n = 1) of the times, respectively. …”
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An investigation of endometrial vascularity in normally menstruating women and those in other physiological states using 3D ultrasound imaging
Published 2024“…The uterine and endometrial volume in the postnatal group were nearly double that of the luteal group (P value <0.01 and 0.014, respectively). There was a significant decrease in flow index in the postnatal group compared to the luteal group (P < 0.01), suggesting low flow intensity in the postnatal group. …”
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Dietary L-carnitine and vitamin-E; a strategy to combat ochratoxin-A induced immunosuppression
Published 2018“…The dietary addition of OA alone suppressed the humoral immune responses, however, the exposure of birds to 1.0 mg/kg OA in the presence of LC and/or VE showed a significant reduction in OA induced immunotoxicity. …”
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A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications
Published 2017“…Data were identified for the genes coding for the cytochrome P450 (CYP) enzymes: CYP2C8, CYP2C19, CYP2A6, CYP2D6, CYP2B6, and the P-glycoprotein drug transporter. …”
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71
Comparative Study on Gas-Sensing Properties of 2D (MoS2, WS2)/PANI Nanocomposites-Based Sensor
Published 2022“…The composite films also exhibited response and recovery times of 10/16 and 14/16 s. Therefore, the composite PANI/2D-TMDs is a suitable material for NH3 gas detection applications.…”
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72
Study of the Ion Interclation Mechanism in Mxene Membrane for the Water Treatment Applications
Published 2020“…MXene membrane consists of free-standing layers of a 2D material, namely MXene, which is attracting growing interest due to its conductivity and well-defined interlayer distance and slit-like channels, making it attractive in applications like energy storage and water treatment applications. …”
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Administration error of benzathine penicillin G in a Saudi male
Published 2019“…The creatinine concentration fluctuated between 0.8 and 1 mg/dL. Conclusion This was an obvious case of a drug‐related problem categorised as a ‘wrong route error’. …”
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Potential of halophytes as cattle fodder : A case-study in Pakistan
Published 2016“…Feeding Berseem (Trifolium alexandrinum, 15% crude protein) as the only source of concentrate in a diet containing D. bipinnata sustained weight only for about 6-7 weeks after which it started to decrease. …”
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The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes
Published 2017“…We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …”
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Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats.
Published 2020“…CsA increased blood pressure (by 46mmHg) and decreased creatinine clearance (by 49%, all P<0.05). …”
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Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
Published 2021“…Ochratoxin A (OTA), an important fungal metabolite in foods and feeds has been shown to induce oxidative stress and cellular injuries to human and animal subjects. …”
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