Generation and Characterization of Conditional Heparin-Binding EGF-Like Growth Factor Knockout Mice by Atsushi Oyagi (165473)

“…These knockout mice showed (a) behavioral abnormalities similar to those described in psychiatric disorders, which were ameliorated by typical or atypical antipsychotics, (b) altered dopamine and serotonin levels in the brain, (c) decreases in spine density in neurons of the prefrontal cortex, (d) reductions in the protein levels of the NR1 subunit of the <em>N</em>-methyl-D-aspartate (NMDA) receptor and post-synaptic protein-95 (PSD-95), (e) decreases in the EGF receptor, and in the calcium/calmodulin-dependent protein kinase II (CaMK II) signal cascade. …”

Effects of under-sampling on analysis of bout duration distributions. by Matt T. Bianchi (236029)

“…Bout durations from four randomly selected individuals, are shown in panels B–D, including the single patient shown in panels A1–3 (which corresponds to patient #4 in panels B–D), to illustrate how the distributions can visually or statistically (asterisk) be mistaken as Gaussian. …”

Modulation of cardiovascular function by rooibos in adults at risk for cardiovascular disease by Maria Diana Hartnick (7007012)

“…Objective 2: The effect of daily Rooibos consumption over 12 weeks on the cardiovascular system included the following outcomes: grade 1 diastolic dysfunction counts decreased from 63 (28%) to 47 (21.5%), grade 2 diastolic dysfunction decreased from 46 (21%) to 24 (11%) and grade 3 diastolic dysfunction decreased from 5 (2.3%) to 3 (1.4%). …”

Full-length AKAP13 mRNA levels are reduced by the gene-trap events. by Matthew J. Spindler (407529)

“…<p>(A) TaqMan gene expression assays were used to measure the expression of AKAP13 transcripts at the indicated exon-exon junctions (E4-5, Brx-9, & E37-38). …”

Oscillation rate tuning. by Mark Campanelli (251746)

“…Clock protein levels are shown for the first of two coupled cells for the parameter set selection giving min with differential decay (A–D), and with differential decay changed to linear decay (E). …”

Early AMD-like degeneration in <i>Nrf2^−/−</i> mice. by Zhenyang Zhao (295966)

“…(E and F) Scotopic ERG recordings at +10 dB (25 cd·s/m²) flash intensity, showing significantly decreased a- and b-wave amplitudes in <i>Nrf2</i>^−/− mice when compared to age-matched wild-type mice (n = 6 per group; *<i>P</i><0.05, ** <i>P</i><0.01, Student's t-test).…”

Variation of PA/DAG ratio modulates the sensitivity and dose response of the pathway. by Jamie L. Nosbisch (8681709)

“…<p><b>(A)</b> The final steady-state concentration of PA (<i>d</i>_<i>p</i>) is plotted versus the concentration of DAG (<i>d</i>) at the front of the cell for each simulation presented in <b><a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007708#pcbi.1007708.g002" target="_blank">Fig 2</a></b>. …”

Table1_Feasibility on equivalence ratio measurement via OH*, CH*, and C2* chemiluminescence and study of soot emissions in co-flow non-premixed DME/C1–C2 hydrocarbon flames.XLSX by Abdallah Abu Saleh (17748816)

“…The 1D simulation showed a non-monotonic correlation between OH*/CH* ratios and equivalence ratios, implying a limited use of OH*/CH* for the equivalence ratio measurement in non-premixed flames with DME additions.…”

DataSheet1_Feasibility on equivalence ratio measurement via OH*, CH*, and C2* chemiluminescence and study of soot emissions in co-flow non-premixed DME/C1–C2 hydrocarbon flames.PDF... by Abdallah Abu Saleh (17748816)

“…The 1D simulation showed a non-monotonic correlation between OH*/CH* ratios and equivalence ratios, implying a limited use of OH*/CH* for the equivalence ratio measurement in non-premixed flames with DME additions.…”

Mitochondrial genome sequencing with short overlapping amplicons on MiSeq FGx system by Yang Xin (286771)

“…In this study, we employed the strategy of short overlapping amplicons for the whole mitogenome, library preparation with tagmentation using the Nextera® XT DNA Library Preparation Kit, sequencing on the MiSeq FGx^TM Forensic Genomics System and analyzing data using the mitochondrial(mtDNA) MSR Plug-in and the mtDNA Variant Analyzer. A total of 27 libraries and 56 libraries were sequenced in a run using MiSeq Reagent Kit v2 and v3, respectively. …”

Differential Proteome Analysis of Bone Marrow Mesenchymal Stem Cells from Adolescent Idiopathic Scoliosis Patients by Qianyu Zhuang (224501)

“…Among these proteins, five related to bone growth and development, including pyruvate kinase M2, annexin A2, heat shock 27 kDa protein, γ-actin, and β-actin, were found to be dysregulated and therefore selected for further validation by Western blot analysis. …”

Supplementary Material for: Intralesional Triamcinolone for Fistulous Tracts in Hidradenitis Suppurativa: An Uncontrolled Prospective Trial with Clinical and Ultrasonographic Follo... by Álvarez P. (6749003)

“…Mean clinical size decreased from 17.0 to 5.1 mm (<i>p</i> < 0.0001), while mean length on ultrasound decreased from 16.0 to 8.6 mm (<i>p</i> < 0.0001). …”

NPS rapidly weakens evoked neuronal activity flow from the DG to area CA1 in hippocampal slices prepared from C57BL/6N mice. by Julien Dine (369093)

“…B, Time course of the experiments depicted for the CA1 output subfield of the VH. NPS (1 µM) decreased FDS peak amplitudes (84±5% of baseline, n = 7 slices from 6 mice). …”

Resveratrol suppresses NSCLC cell growth, invasion and migration by mediating Wnt/β-catenin pathway via downregulating SIX4 and SPHK2 by Xiaolan Wang (317443)

“…<p>Resveratrol (RSV) has been found to have a cancer-suppressing effect in a variety of cancers, including non-small cell lung cancer (NSCLC). …”

Image1_Construction of ceRNA network and identification of hub genes in aniridia-associated keratopathy using bioinformatics analysis.JPEG by Jiawen Wu (63886)

“…Differentially expressed lncRNAs, miRNAs, and mRNAs were analyzed using “limma” packages and weighted gene co-expression network analysis (WGCNA). A ceRNA network was constructed by Cytoscape 3.9.1, and miR-224-5p, miR-30a-5p, and miR-204-5p were at the center of the network. …”

Trends in China’s anthropogenic emissions since 2010 as the consequence of clean air actions by Bo Zheng (5701343)

“…To tackle the problem of severe air pollution, China has implemented active clean air policies in recent years. As a consequence, the emissions of major air pollutants have decreased and the air quality has substantially improved. …”

Detrended fluctuations analysis (DFA) α1 and α2. by Yujie Zhu (618667)

“…ΔDFA α1 represents the increased average heart rate at 6 AM-noon vs midnight-6 AM, and was decreased with CHF. (D) Summarized data of average DFA α2 at baseline, 240 days and 720 days after AC. …”

GTA reduces ASPA expression and inhibits oligodendrocyte differentiation. by Patrick M. Long (487632)

“…D) GTA decreased ASPA levels in Hs683 and HOG cells, but not Oli-Neu cells. …”

DataSheet1_Microbial diversity and potential functional dynamics within the rhizocompartments of Dendrobium huoshanense.docx by Guijuan Xie (8619840)

“…Interestingly, a high proportion of fungi with unknown functions were found in the endosphere, highlighting an area for further research regarding the medicinal efficacy of D. huoshanense. …”

Substitution of dry corn grain by rehydrated and ensiled corn grain, finely or coarsely ground, on performance of young bulls finished in feedlot by Marlon Richard Hilário da Silva (5889929)

“…Ensiling corn grain decreased DMI by 10.3% (11.6 vs. 10.4 kg/d for dry and ensiled, respectively) and increased feed efficiency by 13.3% (0.13 vs. 0.15 kg/d for dry and ensiled, respectively), but there was no effect of particle size, grain source, and their interaction on ADG. …”