NSC population and proliferation decrease drastically during the second postnatal week of DG development. by Cristina Medina-Menéndez (21800157)

JBPOS0101 decreased Amyloid Beta (Aβ) aggregates in the cortex and hippocampal regions in 5xFAD mouse brains. by Jihoon Jeong (4852690)

GluN2A(D731N) reduces the agonist potency. by Kai Gao (120150)

Subjects:

High glucose induces a mild decrease in KIF5B but does not affect the overall content and distribution of tau, KIF1A and dynein in hippocampal cultures. by Filipa I. Baptista (145150)

Knockdown of endogenous Cdk-5 decreases T-type Ca2+ channel functional expression. by Aida Calderón-Rivera (701054)

CD5-2 decreases established CCM lesions in the hindbrain of <i>Ccm2</i>^<i>ECKO</i> mice and lesions in the retina of <i>Ccm2</i>^<i>ECKO</i> mice. by Jia Li (160557)

Decreased responsivity to mechanical stimuli during DRN 5-HT neurons photostimulation. by Guillaume P. Dugué (620333)

eNOS phosphorylation increased intracellular ROS generation and decreased cell viability in BH4-depleted cells. by Hu Peng (396074)

“…<p>(A) HEK 293 cells were treated with DMSO or 10mM DAHP for 24 hours to deplete BH4, then transfected with either control vector or WT eNOS plasmid DNA overnight. …”

Selective downregulation of SR Ca²⁺ handling proteins and decreased SR Ca²⁺ uptake in TG mice hearts. by Mayilvahanan Shanmugam (691549)

“…For each atrial Ca²⁺ uptake experiment, atria from four mice were pooled. n = 4 for each group. The V_max of Ca²⁺ uptake was obtained at pCa 5.5.…”

CsA reduces Flk1 protein expression and significantly decreases the percentages of Flk1+ cells. by Seung-Cheol Choi (686982)

“…(D) Flow cytometric quantification of Flk1+ cells at 48 and 96 h after 0.32 μM CsA treatment during EB formation by P19 cells. …”

Knockdown of AR expression decreases the efficiency of KSHV infection in endothelial cells. by Xing Wang (154377)

“…Values were normalized to the level of actin mRNA and calibrated by comparison to a control siRNA treatment. (d) AR inhibition leads to a significant reduction of the number of internalized KSHV DNA copies. …”

Summary of the A19D unfolding pathway highlighting the main structural changes identified here that might explain its decreased thermodynamic stability. by Priscila Ferreira (498747)

GluN2A(D731N) enhances sensitivity to endogenous proton and zinc ions. by Kai Gao (120150)

Subjects:

Excessive LF4A kinase activity shortens cilia and decreases IFT. by Yu-Yang Jiang (7036916)

Stabilization of Hif-1α at early stages of infection leads to a decrease in bacterial burden. by Philip M. Elks (324793)

“…<p>(A) Quantification of bacterial burden by fluorescent pixel count after DMOG treatment between 5 and 6 dpi. …”

Metformin decreases ATP levels in medium containing low glucose (2.5 mM). by Yongxian Zhuang (634693)

Chemically inhibiting LDHA or PDK1 decreases cell viability in Aβ resistant cells. by Jordan T. Newington (223389)

“…Similarly, 48 hr Aβ exposure significantly decreased cell viability in both PC12 (<b>C</b>) and B12 (<b>D</b>) resistant lines when cells were co-treated with 2.5 mM dichloroacetate (DCA), a chemical inhibitor of PDK1 (*P<0.01). …”

HDACi exposure in DHA-treated cells enhanced decreases of Mcl-1 and p-ERK. A. by Chris Zhiyi Zhang (111721)

Decreased PMA-induced reactive oxygen species production in CD macrophages. by Christine D. Palmer (257323)

Ibuprofen and diclofenac decrease lactate levels and LDH activity. by Verena Leidgens (815986)

“…Diclofenac treatment resulted in a significant decrease of lactate at all concentrations and in all cell lines. …”