A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice by Hiroaki Yashiro (2231686)

“…Here, we demonstrate reduced insulin resistance and the anti-obesity effect of a D5D selective inhibitor (compound-326), an orally active small-molecule, in a high-fat diet-induced obese (DIO) mouse model. …”

Hsp90 depletion decreases stress resistance. by Michelle D. Leach (108675)

Decreased <i>Resf1</i> in cell lines paradoxically decreases metastatic capacity. by Megan R. Majocha (18529925)

Knockdown of Hsp90α or Hsp90β with siRNA decreased the proportion of extracellular FN matrix. by Morgan C. Hunter (513136)

Inhibition of TRPC3 decreases ATP- and OAG-induced Ca²⁺ transients in striatal astrocytes. by Karin M. Streifel (653838)

“…Prior treatment with Pyr3 for 30 minutes at 37°C decreased the Ca²⁺ response to ATP, whereas only a modest additive effect was observed with Pyr3 in the presence of 10 µM MPP⁺. …”

Frequency of IL-17 and/or IL-22 expressing mucosal CD4+T cells decreases by progression of Fiebig stage. by Alexandra Schuetz (327671)

“…<p>To quantify the expression of Il-17 and IL-22 in CD4+T cells, mucosal and peripheral mononuclear cells were stimulated for 5 hours with 40 ng/mL PMA and 1 µM Ionomycin. Gating strategy of sigmoid colon Th17 and Th22 CD4+T cells is shown for a FI subject (<b>a</b>) and representative flow cytometry plots including unstimulated controls (unstim) gated on CD4+T cells showing expression of IL-17 and/or IL-22 in FI (<b>b</b>), FIII (<b>c</b>) and FV (<b>d</b>) in the sigmoid colon. …”

siRNA treatment decreases ADAMTS-1 nuclear pattern in MDA-MB-231 cells. by Suély V. Silva (3233223)

“…<p>(A) Immunofluorescence shows reduced area of ADAMTS-1 (red) at nuclei with siRNA treatment. …”

Supplementary Material for: 3,4-Methylenedioxymethamphetamine (Ecstasy) Decreases Inflammation and Airway Reactivity in a Murine Model of Asthma by Stankevicius D. (4130146)

“…We also showed that MDMA decreased expression of both Th2-like cytokines (IL-4, IL-5 and IL-10) and adhesion molecules (L-selectin). …”

αTAT1 increases acetylated alpha-tubulin in distal axons and HDAC5 decreases acetylated alpha-tubulin along the length of the axon. by Shen Lin (519157)

Oxytocin decreases postsynaptic CeA spontaneous GABAergic transmission and blocks presynaptic alcohol effects. by Brendan J. Tunstall (6593357)

“…^#Significant difference between groups (<i>p</i> < 0.05). Amp, amplitude; CeA, central nucleus of the amygdala; EtOH, ethanol; Freq, frequency; mIPSC, miniature inhibitory postsynaptic current; OT, oxytocin; OTA, desGly-NH2-d(CH2)5[D-Tyr2,Thr4]OVT; sIPSC, spontaneous inhibitory postsynaptic current; TTX, tetrodotoxin.…”

The recruitment of MYD88 to TLR2 and IRAK-4 phosphorylation are decreased in β3-integrin–silenced cells. by Tatiana Gianni (499634)

MyD88^-/- mice have decreased levels of cytokines in the conjunctiva. by Rose Y. Reins (2586106)

Supplementary Material for: Use of the Myocardial Performance Index in Decreased Fetal Movement Assessment: A Case-Control Study by Ho D. (4108837)

A decrease in the amount of HBV nucleocapsids occurs when there is overexpression of singly-spliced2.2 kb RNA <i>in vivo</i>. by Yi-Ling Wang (704612)

Expression levels of miR-182 in endometrium at D5 and D15. by Lei Zhang (38117)

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Algal oil and Meganol D decreased early vascular lesions and upregulate plasma SPM in APOE^-/- mice. by Agua Sobrino (368634)

Silencing <i>cullin-1/5</i> decreased mRNA and protein expression of NF-κB dependent cytokines. by Attinder Chadha (11414273)

Subjects:

Five compounds significantly decrease MAPK1 phosphorylation in K562 cells. by Pamela Y. Ting (713174)

Nimodipine does not decrease markers of neuritic dystrophy in 5XFAD transgenic mice. by Katherine R. Sadleir (12035242)

“…<p><b>(</b>A and F) Representative immunoblots of hippocampal (A) and cortical (F) lysates of non-transgenic and 5XFAD mice treated with vehicle or nimodipine. …”