Modulation of the persistent histamine responses by [Ca]_i and PKA. by Iustin V. Tabarean (302441)

“…Extracellular incubation with BAPTA-AM (1 mM) gradually decreases a persistent current activated by histamine (50 µM). …”

Neuregulin 1 type III (Nrg1III) overexpression worsens the radial sorting defects of Lama2^−/− mice. by Monica Ghidinelli (4164244)

“…Bar = 10 μm in A, 2 μm in B and D. The numerical data used in C–C” are included in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2001408#pbio.2001408.s001" target="_blank">S1 Data</a>.…”

Zebrafish Caudal Fin Angiogenesis Assay—Advanced Quantitative Assessment Including 3-Way Correlative Microscopy - Fig 4 by Ruslan Hlushchuk (56116)

“…<p><b>DAA: Assessment of the anti-angiogenic effects of PTK787 at different concentrations 50, 100, 250, 500 nM: a-c</b> Fluorescent images of regenerating caudal fins at 3 (<b>a</b>^<b>1</b><b>-c</b>^<b>1</b>), 5 (<b>a</b>^<b>2</b><b>-c</b>^<b>2</b>) and 7 dpa (<b>a</b>^<b>3</b><b>-c</b>^<b>3</b>) under 3 different conditions: vehicle control (left column), 100 nM (middle) and 500 nM PTK787 (right column). …”

Frequency of the top ten actionable phenotypes in Hong Kong Chinese compared to that of Africans and Europeans. by Mullin Ho Chung Yu (10039535)

“…Actionable phenotypes include <i>CYP2C19</i> IM and PM; <i>CYP3A5</i> EM and IM; <i>CYP2B6</i> IM and PM; carrier of <i>CYP4F2</i> decreased function allele; carrier of <i>HLA-B</i>*15:02; *57:01 and *58:01; <i>SLCO1B1</i> intermediate and low-function diplotypes; <i>NUDT15</i> IM and PM; <i>IFNL3</i> unfavorable response genotype; <i>CYP2D6</i> UM, IM, and PM; and <i>CYP2C9</i> IM and PM. …”

Monitoring of Diaphorina citri populations from Florida reveals reduced susceptibility to cyantraniliprole and thiamethoxam by Xuedong Chen (11951135)

“…A bottle bioassay method was used to measure direct toxicity of insecticides to <i>D. citri</i>. …”

Downregulated expression and enrichment of cancer genes among highly targeted genes by Lawrence S Hon (47277)

“…In a comparison of highly targeted genes (n > 20) versus less targeted genes (1 ≤ n ≤ 5) in normal tissue samples [46], 121 out of 158 samples exhibited decreased expression among highly targeted genes (= 1 × 10). …”

Comparison of platelet count, VWF:Ag, ADAMTS13:AC, AST, and T-Bil between patients treated with and not treated with bevacizumab. by Naoto Nishigori (828276)

“…<p>(A) Platelet counts decreased until months 3 as the number of chemotherapy cycles increased in both patients who received and did not receive bevacizumab. …”

Changes in hepatic IL-1β mRNA expression after hemorrhage. by Hiroaki Sato (207336)

“…In contrast, the serum IL-1β level in the FR+Hemorrhage group showed no change from the baseline value throughout the experiment. Data are shown as mean±SE. n = 5/groups, * p<0.05 vs Sham, + p<0.05 between Hemorrhage and FR+Hemorrhage.…”

Functionalization of reverse osmosis membrane with graphene oxide to reduce both membrane scaling and biofouling by Ashfaq M.Y.

Get full text
Get full text
Get full text

Adaptation enhances discrimination at the cost of reduced detection: Temporal coding. by Wesley P. Clawson (4053658)

“…<p>(<b>A</b>) The time course of population response during the 1 s (0.2 s resolution) following the four different foreground stimuli (red dots) showed little difference during the transient response. …”

Oridonin inhibited angiogenesis in vitro. by Yanmin Dong (107414)

“…<p>(A) The chemical structure of Oridonin (Raddosia rubescens) (left panel) and the MTS assay of HUVECs (right). 5×10³ HUVECs were seeded in each well of 96-well plates, and incubated with the indicated concentration of Oridonin after cell adhesion. 490 nm absorbance was measured after 48 hours treatment. …”

Reduced control model M4: Normative evidence accumulation. by Veith Weilnhammer (2909060)

“…(<b>D</b>) In the normative-evidence-accumulation model, the smoothed probabilities of stimulus- and history-congruence (sliding windows of ±5 trials) fluctuated as a scale-invariant process with a 1/f power law, i.e., at power densities that were inversely proportional to the frequency (power ∼ 1/<i>f</i>^<i>β</i>; stimulus-congruence: <i>β</i> = −0.78 ± 1.1×10⁻³, T(1.92×10⁵) = −706.93, <i>p</i> < 2.2×10⁻³⁰⁸; history-congruence: <i>β</i> = −0.79 ± 1.12×10⁻³, T(1.92×10⁵) = −702.46, <i>p</i> < 2.2×10⁻³⁰⁸). …”

The synthetic lethality of the <i>erd1</i>Δ mutation with the Neo1p-depleted <i>cfs1</i>Δ mutation is not caused by reduced levels of cytoplasmic Pi. by Mamoru Miyasaka (9187916)

“…Cells were grown and spotted, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0236520#pone.0236520.g001" target="_blank">Fig 1B</a>, in YPGA (galactose) or YPDA (glucose) medium with either 20 mM Pi or 50 mM Pi and then incubated at 30°C for 1.5 d. …”

DataSheet1_Modeling semiconducting silicene nanostrips: electronics and THz plasmons.docx by Talia Tene (15443348)

“…Our results reveal that SiNSs with widths ranging from 100 to 500 nm exhibit small bandgaps within the range of a few meV, specifically ranging from 30 to 6 meV, respectively. …”

Impact of recBCL-XL (ΔTM) microinjection on early embryo development. by Xinyu Liu (34266)

“…In addition, total cell number (TCN) per embryo was significantly increased and cell death index (CDI) was decreased (n = 71 for buffer injection; n = 110 for protein injection). …”

Enhanced Gene Expression Rather than Natural Polymorphism in Coding Sequence of the <i>OsbZIP23</i> Determines Drought Tolerance and Yield Improvement in Rice Genotypes by Avishek Dey (1693921)

“…<i>rufipogon</i> and drought-sensitive IR20 cultivar showed variation in the number of stress-responsive <i>cis</i>-elements and a 35-nucleotide deletion at 5’-UTR in IR20. Analysis of the <i>GFP</i> reporter gene function revealed that the promoter activity of <i>O</i>. …”

Impact of Xpert MTB/RIF Testing on Tuberculosis Management and Outcomes in Hospitalized Patients in Uganda by Christina Yoon (121836)

“…However, our study did not detect a decrease in two-month mortality following implementation of Xpert MTB/RIF possibly because of insufficient powering, differences in empiric TB treatment rates, and disease severity between study phases.…”

Supplementary Material for: Successful Reperfusion with Endovascular Therapy Has Beneficial Effects on Long-Term Outcome Beyond 90 Days by Todo K. (5732024)

“…<b><i>Results:</i></b> A total of 268 patients were included in the current study. …”

Mitochondrial Apoptotic Pathway Is Activated by H₂O₂-Mediated Oxidative Stress in BmN-SWU1 Cells from <i>Bombyx mori</i> Ovary by Peng Chen (6514)

“…Furthermore, western blot analysis revealed a significant increase in p53 and cytochrome c expression, and a decrease in Bcl-2 expression compared to the controls. …”

Impact of Manganese Carbonate Precipitation on Uranium(VI) Fate in Conditions Relevant to Carbonate-Buffered Aquifers by Surya Sujathan (11355082)

“…Reactive modeling of Mn and DIC data exhibited a decrease in the surface area normalized rate constants of MnCO_3(s) precipitation from 5.9 to 3.3 × 10^–8 mol m^–2 h^–1 with an increase in initial U(VI) from 0 to 500 μM. …”