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  1. 1821

    A brief course of RAP treatment decreases markers of proliferation and increases markers of differentiation. by Karin M. Hardiman (555189)

    Published 2014
    “…<p><i>CDX2P-CreER<sup>T2</sup> Apc<sup>fl/fl</sup></i> mice were injected with TAM and monitored until polyposis was seen endoscopically, then the mice were treated with vehicle or RAP at 3 mg/kg concentration for periods of one, three, or five days (N = 5 per timepoint). (A) and (B) Immunostaining of distal colons from these mice or Cre negative <i>Apc<sup>fl/fl</sup></i> mice for phospho-mTOR and phospho-S6. …”
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