Effect of IL-10 receptor (IL-10R) blockade upon leukomyelitis in Theiler’s murine encephalomyelitis virus (TMEV)-infected SJL mice. by Ann-Kathrin Uhde (3110976)

“…Almost no CD3⁺ T cells were present in spinal cord cross sections of mock-infected animals. (D) Simultaneously, IL-6 mRNA expression significantly decreased in TMEV-infected animals following IL-10R blockade. white box = TMEV-infected mice without IL-10R Ab treatment (group “isotype_late/TMEV”), grey box = TMEV-infected mice with IL-10R treatment (group “IL10R↓_late/TMEV”), black box = mock-infected mice with IL-10R treatment (group “IL10R↓_late/mock”). …”

Fluorogenic Dimers as Bright Switchable Probes for Enhanced Super-Resolution Imaging of Cell Membranes by Ilya O. Aparin (4435837)

“…The concept was validated on cyanines 3 and 5. SMLM of live cells revealed that the new probes provided higher brightness and ∼10-fold slower diffusion at the cell surface, compared to reference probes Nile Red and DiD, which boosted axial localization precision >3-fold down to 31 nm. …”

F2Pal₁₀ induces pertussis toxin sensitive superoxide production and triggers mobilization of calcium from intracellular stores. by Michael Gabl (642838)

“…The response induced by the peptides was gradually decreased (shown for 90 and 120 min incubation). As a control, the PMA response (5×10⁻⁸ M final concentration) from control cells (120 min incubation without PTX, solid line in the inset) or treated with PTX for 120 min (dashed line in the inset) is shown. …”

The level of noise-induced ABR threshold shifts is correlated with the level of pre-noise cochlear dysfunction in Prestin-CreER^T2 homozygous mice. by Qunfeng Cai (385460)

“…There is a negative correlation between the two variables (Pearson's correlation analysis, <i>r</i> = −0.92, <i>p</i><0.001), indicating that, with the increase in the level of pre-noise hearing dysfunction, the noise-induced threshold shift decreases. …”

Supplementary Material for: How physicians and nursing staff perceive effectiveness and tolerability of Bryophyllum preparations: an online survey in an anthroposophic hospital by Huber T. (3218385)

“…Participants and Methods: All physicians and nursing staff with a valid email address at the hospital “Klinik Arlesheim AG” were invited via email to participate in this REDCap survey. …”

Image_1_Low-Dose Antibiotic Prophylaxis Induces Rapid Modifications of the Gut Microbiota in Infants With Vesicoureteral Reflux.JPEG by William Morello (10984251)

“…</p><p>Conclusions: In infants with VUR, even a short exposure to CAP definitely alters the GM composition, with increased relative abundance of opportunistic pathogens and decreased proportions of health-promoting taxa. …”

ChIP-seq analysis and miRNA expression in wt and mutated MCVSyn genomes. by Juliane Marie Theiss (776252)

“…<p>(<b>A</b>) Schematic depiction of the MCPyV genome with polyadenylation and transcriptional initiation sites as identified by RACE analyses. …”

Image_4_Low-Dose Antibiotic Prophylaxis Induces Rapid Modifications of the Gut Microbiota in Infants With Vesicoureteral Reflux.TIF by William Morello (10984251)

“…</p><p>Conclusions: In infants with VUR, even a short exposure to CAP definitely alters the GM composition, with increased relative abundance of opportunistic pathogens and decreased proportions of health-promoting taxa. …”

Fluorogenic Dimers as Bright Switchable Probes for Enhanced Super-Resolution Imaging of Cell Membranes by Ilya O. Aparin (4435837)

“…The concept was validated on cyanines 3 and 5. SMLM of live cells revealed that the new probes provided higher brightness and ∼10-fold slower diffusion at the cell surface, compared to reference probes Nile Red and DiD, which boosted axial localization precision >3-fold down to 31 nm. …”

Fluorogenic Dimers as Bright Switchable Probes for Enhanced Super-Resolution Imaging of Cell Membranes by Ilya O. Aparin (4435837)

“…The concept was validated on cyanines 3 and 5. SMLM of live cells revealed that the new probes provided higher brightness and ∼10-fold slower diffusion at the cell surface, compared to reference probes Nile Red and DiD, which boosted axial localization precision >3-fold down to 31 nm. …”

Image_2_Low-Dose Antibiotic Prophylaxis Induces Rapid Modifications of the Gut Microbiota in Infants With Vesicoureteral Reflux.TIF by William Morello (10984251)

“…</p><p>Conclusions: In infants with VUR, even a short exposure to CAP definitely alters the GM composition, with increased relative abundance of opportunistic pathogens and decreased proportions of health-promoting taxa. …”

Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models by Estelle Daudigeos-Dubus (829658)

“…<i>In vitro</i> effects on cell proliferation were screened against 33 solid tumor cell lines of the Innovative Therapies for Children with Cancer (ITCC) panel covering five pediatric solid malignancies. Regorafenib inhibited cell proliferation with a mean half maximal growth inhibition of 12.5 μmol/L (range 0.7 μmol/L to 28 μmol/L). …”

Thalamic generation of propofol phase amplitude coupling by Austin Soplata (12089999)

“…We included propofol dose effects by increasing maximal conductance and decay time constant of GABAa-mediated inhibition by either 2X or 3X normal, and by decreasing maximal H-current conductance (gH). We then considered for each a pair of 2-D parameter spaces, varying gH and applied current corresponding to peak and trough phases of the cortical slow wave. …”

Huaier Aqueous Extract Inhibits Ovarian Cancer Cell Motility via the AKT/GSK3β/β-Catenin Pathway by Xiaohui Yan (411294)

“…Western blot analysis further validated that Huaier treatment resulted in decreased AKT phosphorylation, enhanced expression of total GSK3β, inhibition of the phosphorylation of GSK3β on S9, reduction of both cytoplasmic β-catenin expression and nuclear β-catenin translocation, and transcriptional repression of several Wnt/β-catenin target genes (<i>DIXDC1, LRP6, WNT5A</i>, and cyclin D1). …”

Additional HAND2 or microRNA-1 could facilitate the progress of human iCM-reprogramming by GMTEMMZ 7 factors (7Fs). by Emre Bektik (4347667)

“…B) The quantification of three subpopulations in panel A showed that additional HAND2 or microRNA-1 significantly decreased the subpopulation of fibroblast-like reprogrammed iCMs, while the CM-like subpopulation was significantly enhanced only in 12W-7Fs-iCMs. …”

Data_Sheet_1_G721-0282 Exerts Anxiolytic-Like Effects on Chronic Unpredictable Mild Stress in Mice Through Inhibition of Chitinase-3-Like 1-Mediated Neuroinflammation.DOCX by Hyeon Joo Ham (7623410)

“…In the present study, we investigated the anxiolytic-like effect of N-Allyl-2-[(6-butyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-5-yl)sulfanyl]acetamide (G721-0282), an inhibitor of CHI3L1, on mice treated with chronic unpredictable mild stress (CUMS), as well as the mechanism of its action. …”

Data_Sheet_1_Mental health disparities in Latinx immigrant communities residing in the United States during COVID-19: Implications for policy and practice.docx by María Pineros-Leano (10192295)

“…Key themes identified describing the impact of COVID-19 on the mental health needs of Latinx families included: (1) exacerbation of mental health symptoms, (2) financial stressors, (3) preoccupation regarding transnational lives, (4) secondary needs becoming more salient, and (5) immigration status as a main driver of inequality.…”

Image_3_Low-Dose Antibiotic Prophylaxis Induces Rapid Modifications of the Gut Microbiota in Infants With Vesicoureteral Reflux.TIF by William Morello (10984251)

“…</p><p>Conclusions: In infants with VUR, even a short exposure to CAP definitely alters the GM composition, with increased relative abundance of opportunistic pathogens and decreased proportions of health-promoting taxa. …”

Human biliary tree stem cell (hBTSC) differentiation towards pancreatic fate induced <i>in vitro</i> by Pdx1 peptide. by Vincenzo Cardinale (781191)

“…(B, C) In hBTSCs cultured for 14 days in KM containing 0.1 μM Pdx1, the glucagon and somatostatin mRNA levels increased 6- (data are means ± SD of 6 experiments; ***p< 0.001) and 2-folds (data are means ± SD of 6 experiments; **p< 0.01), respectively, in comparison with KM. (D) In hBTSCs cultured for 14 days in KM containing 0.1 μM Pdx1, MafA (4.5-folds) (data are means ± SD of 6 experiments; **p< 0.01) or Pdx1 (2-folds) (data are means ± SD of 6 experiments; **p< 0.01) gene expression increased in comparison with KM, while EpCAM mRNA decreased (average 4-folds) (data are means ± SD of 6 experiments; *p< 0.05).…”

PTEN regulates Maf1 protein expression. by Beth M. Palian (673045)

“…<p>(<b>A</b>) <u>Maf1 expression is decreased in mouse cells and tissues lacking PTEN</u>. …”