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821
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822
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823
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824
Decreased neurogenesis and impaired PPI in MAM-treated wild-type rats.
Published 2009“…(C), PPI defects were observed at pp68 with a startle stimuli of 105 dB at 10 weeks in MAM-treated rats. …”
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825
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826
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827
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828
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829
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830
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831
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832
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833
Decreased FA number in Rgnef−/− MEFs on fibronectin (FN) at 90 min.
Published 2012“…Cells were fixed and analyzed for FA formation by paxillin staining (green), f-actin (phalloidin, red), and nuclei were stained with Hoechst (blue) as shown in a merged image. Scale is 10 µm. Significantly-reduced adhesion number (B) and decreased median adhesion size (C) in Rgnef−/− compared to normal (Rgnef+/+) MEFs. …”
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834
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835
Reduced p53 Activity Decreases Apoptosis but Does Not Increase Proliferation
Published 2013“…<p>Representative apoptosis levels of each mouse line correlate with T<sub>121</sub> expression as indicated by the percentage of TUNEL positive cells (A). Decreasing levels of p53 activity correlate with lower levels of apoptosis in transgenic mammary glands (B). …”
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836
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837
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838
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839
Down-regulation of Gli decreased ovarian cancer cell migration and invasion.
Published 2014“…<p>(<b>A</b>) Exposure to GANT61 (30 µM; 48 hr) reduces expression of both Gli1 and Gli2 protein, determined by Western blot. …”
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840