Image_1_Lung Neutrophilic Recruitment and IL-8/IL-17A Tissue Expression in COVID-19.tiff by Marina Luise Viola Azevedo (10503320)

“…However, the G allele (GG and GA) of rs3819025 was correlated with higher tissue expression of IL-17A in the COVID-19 group. SARS-CoV-2 virus evokes an exacerbated response of the host’s immune system but differs from that observed in the H1N1pdm09 infection since the IL-8/IL-17A tissue expression, and lung neutrophilic recruitment may be decreased. …”

Table_1_Lung Neutrophilic Recruitment and IL-8/IL-17A Tissue Expression in COVID-19.docx by Marina Luise Viola Azevedo (10503320)

“…However, the G allele (GG and GA) of rs3819025 was correlated with higher tissue expression of IL-17A in the COVID-19 group. SARS-CoV-2 virus evokes an exacerbated response of the host’s immune system but differs from that observed in the H1N1pdm09 infection since the IL-8/IL-17A tissue expression, and lung neutrophilic recruitment may be decreased. …”

A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury by Veronica Redaelli (7586621)

“…The aims of this investigation were 1- to assess acute surgical pain in mice subjected to SCI, 2- to compare the efficacy of commonly used analgesia (three buprenorphine subcutaneous injection in 48 hours, 0,15 mg/kg each) with a combination of opioid and NSAID (one subcutaneous injection of 5 mg/kg carprofen before surgery followed by three buprenorphine subcutaneous injection in 48 hours, 0,15 mg/kg each) and 3- to test if Infrared Thermography (IRT) could be a potential new Refinement method to easily assess thermoregulation, an important metabolic parameter. …”

PEA performed at different extension times and different enzyme inactivation times, for three concentrations of rPCT. by Frederic Bedin (3402254)

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity by Brandon L. Probst (727964)

“…Consistent with the direct effect of AIMs on IKKβ, RTA 408 inhibited NF-κB signaling and decreased cyclin D1 levels at the same concentrations that inhibited cell growth and induced apoptosis. …”

Electrocardiogram during the treatment. by Thaysa de Sousa Reis (19338663)

Opercular activity during the recovery. by Thaysa de Sousa Reis (19338663)

Opercular activity during the treatment. by Thaysa de Sousa Reis (19338663)

Electrocardiogram during the recovery. by Thaysa de Sousa Reis (19338663)

Western blot and TR-FRET analyses revealed an age dependent decrease of soluble mutant ataxin-3 levels in cerebellum. by Huu Phuc Nguyen (110694)

“…<p>A–D) Two animals of the indicated genotypes per age were immunoblotted and detected with an ataxin-3 (clone 1H9) antibody. …”

Liquid Crystalline Features in a Polyolefin of Poly(methylene-1,3-cyclopentane) by Naofumi Naga (2084077)

“…A liquid crystalline phase has been discovered in a polyolefin of poly(methylene-1,3-cyclopentane) (PMCP) having low molecular weight, which was obtained with cyclization polymerization of 1,5-hexadiene (HD) using a zirconocene catalyst in the presence of chain transfer reagents. …”

Oral infection with <i>K</i>. <i>pneumoniae</i> is highly pathogenic in elderly mice but not in young adult mice. by Hitoshi Tsugawa (296864)

DataSheet1_Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disord... by Johannes Matthaei (3534620)

“…In a second, independent study sample of 50 patients who underwent amitriptyline therapy of 75 mg twice daily, a significant trend of increasing amitriptyline plasma concentrations with decreasing OCT1 activity was observed (p = 0.018), while nortriptyline plasma concentrations were unaffected by the OCT1 genotype. …”

Description of results of SD-TOPSIS application (combination A) using selected moment characteristics. by Roman Vavrek (13200141)

Model prediction of the IOP with varying MicroShunt lumen diameters. by Inês C. F. Pereira (13607517)

CMPK2 inhibits the replication of multiple pathogenic flaviviruses but not viruses of the <i>Corona-</i>, <i>Orthomyxo-</i>, <i>Paramyxo-</i>, <i>Rhabdo-</i> and <i>Herpes-viridae<... by Joanna B. Pawlak (5210639)

High initiation rates decrease protein output of stall-containing <i>S</i>. <i>cerevisiae</i> mRNAs. by Heungwon Park (3859507)

Data_Sheet_5_P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.docx by Jiawen Zhou (2323381)

“…P16^INK4a deletion could maintain barrier function and microbiota balance in Bmi-1^–/– mice through strengthening formation of TJ and decreasing macrophages-secreted TNF-α induced by Desulfovibrio entering the intestinal epithelium. …”

Data_Sheet_5_P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.docx by Jiawen Zhou (2323381)

“…P16^INK4a deletion could maintain barrier function and microbiota balance in Bmi-1^–/– mice through strengthening formation of TJ and decreasing macrophages-secreted TNF-α induced by Desulfovibrio entering the intestinal epithelium. …”

A model of the interactions from a systemic view showing how TCs affect development. by Bruno César Feltes (407939)

“…TCs are connected to ALOX5 and ALOX15B, which are proteins involved in the synthesis of leukotriene, a molecule that plays pivotal roles in pro-inflammatory responses. …”