Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach. by Agrahari, Ashish Kumar

“…This substitution was identified in both familial and sporadic forms of PD with a higher frequency. Few computational studies have reported the impact of G2019S substitution on inhibitors of the kinase domain of LRRK2. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ibrahim, Ahmed S.

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Evaluating the impact of price regulation (Drug Price Control Order 2013) on antibiotic sales in India: a quasi-experimental analysis, 2008–2018 by Selvaraj, Sakthivel

“…However, in terms of ‘average monthly market share,’ the DPCO 2013 notification resulted in a sharp reduction of 579% (P < 0.05) (level change) followed by a sustained increase of 9.5% (P > 0.05) (trend change) in the ‘market share of antibiotics under DPCO’ as compared to pre-intervention trend. …”
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Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis by Nazmul, Islam

“…Meta-regression showed a significant decrease in SSI incidence in HICs. …”
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Trends in the global, regional, and national burden of oral conditions from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021 by Eduardo, Bernabe

“…Increasing counts of prevalent cases and DALYs were noted for all oral conditions but untreated caries of deciduous teeth (no percentage change in prevalence or DALYs) and orofacial clefts (–68·3% [–79·3 to –46·5] decrease in DALYs). There were decreases in both age-standardised prevalence and DALY rate for untreated caries of permanent teeth and edentulism, no change in both for untreated caries of deciduous teeth and severe periodontitis, an increase in the prevalence but no change in the DALY rate for lip and oral cavity cancer, and no change in the prevalence but a decrease in the DALY rate for orofacial clefts. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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Seasonal weather conditions affect training program efficiency and physical performance among special forces trainees: A long-term follow-up study by Dhahbi W.

“…These training-cycles induced a significant increase (p<0.05) in the 70-seconds push-ups, pull-ups and sit-ups and a decrease (p<0.01) in the 5-km cross-country running time among all trainees. …”
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil, Shallik

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil, Shallik

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
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Accelerated weathering effects on poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and PHBV/TiO2 nanocomposites by Antunes, A.

“…It also slowed down the decrease in mechanical properties. The mechanical properties were shown to gradually decrease for the PHBV/TiO2 nanocomposites, whereas a sharp drop was observed for the neat PHBV after an accelerated weathering exposure. …”
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Artificial weathering and accelerated heat aging studies on low-density polyethylene (Ldpe) produced via autoclave and tubular process technologies by Luyt, A. S.

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Microstructural, tribological and compression behaviour of Copper matrix reinforced with Graphite-SiC hybrid composites by Jamwal, A.

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A Methodology for daylight optimisation of high-rise buildings in the dense urban district using overhang length and glazing type variables with surrogate modelling by Ekici B.

“…Integrating daylight performance in building design supports reducing the energy consumption and satisfying occupants' comfort. This study presents a methodology to optimise the daylight performance of a high-rise building located in a dense urban district. …”
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Anticoagulant activity of cellulose nanocrystals from isora plant fibers assembled on cellulose and sio2 substrates via a layer-by-layer approach by Mohan T.

“…In this study, we report the isolation of cellulose nanocrystals (CNCs) from Isora plant fibers by sulfuric acid hydrolysis and their assembly on hydrophilic cellulose and silicon-di-oxide (SiO2) surfaces via a layer-by-layer (LBL) deposition method. The isolated CNCs were monodis-persed and exhibited a length of 200-300 nm and a diameter of 10-20 nm, a negative zetapotential (34-39 mV) over a wide pH range, and high stability in water at various concentrations. …”
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Growth performance, intestinal histomorphology, gut microflora and ghrelin gene expression analysis of broiler by supplementing natural growth promoters: A nutrigenomics approach by Gilani, S.M.H.

“…In an epoch of escalating number of antibiotic-resistance bacteria, there is a dire need to develop efficient and novel feeding strategies for animal nutrition as alternatives to antibiotics. …”
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A precious-metal-free Fe-intercalated carbon nitride porous-network with enhanced activity for the oxygen reduction reaction and methanol-tolerant oxygen reduction reaction by Bin Yousaf, Ammar

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A Reduction in Maximal Incremental Exercise Test Duration 48 h Post Downhill Run Is Associated with Muscle Damage Derived Exercise Induced Pain. by Chrismas, Bryna C R

“…Conclusion: EIMD resulted in premature termination of a MIE test (decreased TTE), which was associated with EIP, MVC, and VA. …”
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Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial. by Alam, Mohammed Fasihul

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Antagonistic Effects of Trichoderma harzianum Isolates against Ceratocystis radicicola: pioneering a Biocontrol Strategy against Black Scorch Disease in Date Palm Trees by Al-Naemi, Fatima A.

“…The aim of this study was to develop a method of biological control through the isolation, identification and examination of the effectiveness of bioagents in controlling black scorch disease. …”
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