Islets from hyperglycemic GK rats exhibit decreased proteasome activities together with increased cleaved PARP levels. by Christophe Broca (538652)

Increasing the number of commonly represented features decreases the assignment error rate, but increases the level of redundancy between the representations. by W. Jeffrey Johnston (8463480)

“…<p>The color legend is the same throughout the plot, and provided in <b>D</b>. <b>A</b> Schematic showing that the distance between two points increases with the dimensionality of the space that they are in. …”

EDN3 is associated with decreased levels of RA receptor mRNA and RA metabolic enzyme mRNA. by Jonathan M. Gisser (456149)

“…(D) EDN3 also reduced <i>Cyp26a1</i> mRNA levels, but only in the presence of RA. …”

Overexpression of <i>EVI1</i> decreases the sensitivity of U937 cells to drugs used in AML therapy. by Anna Rommer (241040)

VEGF and sFlt-1 mutants exhibit changes in stem cell marker gene expression by RT-qPCR. by Christopher R. Schlieve (3179439)

“…<p>(A) VEGF mutants demonstrated 0.55-fold reduction in Lgr5 expression compared to littermates (*p = 0.04). …”

Free energy landscape between PC1 and PC2 of native and mutant complexes. by Sneha P. (3926957)

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Video_2_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Video_3_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Image_2_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TIF by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Image_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TIF by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Video_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Mean probability of reporting a specific health status in non-hypertensive and hypertensive patients, with and without related medication, while excluding the effects of other fact... by Jesús Martín-Fernández (406234)

Activity of hepatic injury associated enzymes was decreased in CD44KO(HFD) compared to WT(HFD) mice. by Hong Soon Kang (386679)

Treatment of filarial infection is associated with decreased F_o of antigen – specific Th2 subsets. by Rajamanickam Anuradha (129298)

Lentivirus shRNA knockdown experiment and MTT analysis showing the effect of bortezomib/venetoclax on the cell viability of sLCL 381 and 421 panels. by Kam Pui Tam (19746865)