Oxidative and Anti-Oxidative Stress Markers in Chronic Glaucoma: A Systematic Review and Meta-Analysis by Cédric Benoist d’Azy (2817379)

“…We demonstrated an overall increase in oxidative stress markers in glaucoma (effect size = 1.64; 95%CI 1.20–2.09), ranging from an effect size of 1.29 in serum (95%CI 0.84–1.74) to 2.62 in aqueous humor (95%CI 1.60–3.65). Despite a decrease in antioxidative stress marker in serum (effect size = –0.41; 95%CI –0.72 to –0.11), some increased in aqueous humor (superoxide dismutase, effect size = 3.53; 95%CI 1.20–5.85 and glutathione peroxidase, effect size = 6.60; 95%CI 3.88–9.31). …”

FIGURE 2 from D-2-HG Inhibits <i>IDH1^mut</i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation by Sean T. Pianka (18237413)

“…<p>IDH1^mut production of D-2-HG inhibits gliomasphere growth. IDH1^mut inhibitors (C35 = 2 µmol/L; AG881 = 1 µmol/L) enhance growth of <i>IDH1^mut</i><b></b>patient-derived gliomaspheres HK252 (<b>A</b>) and HK211 (<b>B</b>). …”

DYRK1A activity on HBV transcription regulatory regions. by Florentin Pastor (19852287)

Norgestrel dampens pro-inflammatory microglial activity <i>in vivo</i> and decreases DAMP release from photoreceptors. by Sarah L. Roche (452321)

The process of data collection and annotation by drones. by Junyan Wang (4738518)

Subjects:

Visualization of heatmaps before and after improvement. by Junyan Wang (4738518)

Subjects:

Comparison of effects before and after improvement. by Junyan Wang (4738518)

Subjects:

Effect of single or combined DYRK1A/DYRK1B KD in HBV-infected PHHs. by Florentin Pastor (19852287)

“…Western blot analysis was performed at 7-dpt. Cyclin D1 levels were analyzed as a marker of functional DYRK1 KD, since its accumulation has been shown to depend on both DYRK1A and DYRK1B [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0311655#pone.0311655.ref058" target="_blank">58</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0311655#pone.0311655.ref076" target="_blank">76</a>]. …”

Expression levels of JAM-A, VE-cadherin, and integrin-α5 in the I/R-injured hearts with or without TXL treatment. by Kang Qi (703361)

“…<p>I/R injury decreased the expression levels of JAM-A (A), VE-cadherin (B), and Integrin-α5 (C). …”

Table_5_FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis.docx by Shanshan Xu (276428)

Bacteria quantification (<i>Lactobacillus</i> (L) and <i>Acetobacter</i> (A)) in P0 pupae and pharate adults in wild-type and <i>drs</i> mutants. by Catarina Nunes (3542330)

“…<p><b>(A-B)</b> In control flies <i>({w-}</i>;+;+), the number of pupae with more bacteria decreases between P0 and pharate adult stages. …”

Image_5_Intranasal Delivery of Recombinant S100A8 Protein Delays Lung Cancer Growth by Remodeling the Lung Immune Microenvironment.tif by Sze Wing Wong (1617550)

G2019S LRRK2 modulates Tf recycling in iPSC-derived human microglia. by Adamantios Mamais (302600)

“…G2019S LRRK2 iPSC microglia exhibited larger Tf vesicles compared to WT while LPS treatment induced a decrease in average vesicle size in both cohorts (C) (minimum 3,000 vesicles were counted from 16 cells per group from 2 differentiations, two-way ANOVA, genotype: <i>P</i> < 0.0001, F(1,17753) = 16.38, treatment: <i>P</i> < 0.0001, F(1,17753) = 20.57). …”

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV‑2 Main Protease by Julia M. Flynn (16475720)

“…Drugs that target the main protease (M^pro) of SARS-CoV-2 are effective therapeutics that have entered clinical use. …”

Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV‑2 Main Protease by Julia M. Flynn (16475720)

“…Drugs that target the main protease (M^pro) of SARS-CoV-2 are effective therapeutics that have entered clinical use. …”