Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Patterns of Gene and Metabolite Define the Effects of Extracellular Osmolality on Kidney Collecting Duct by Hyo-Jung Choi (317873)

“…Integrated analysis of the transcriptome and metabolome revealed that decreased extracellular osmolality was associated with decreased levels of organic osmolytes, glucose, intermediates of citric acid cycle, and branched-chain amino acids (BCAA) in IMCD cells, along with significantly decreased gene expression and protein abundance of P-type transporters (ATP1B1), ABC transporters (ABCC5 and ABCG1), and insulin signaling pathways (IRS2). …”

Integrating expression data, regulatory motif conservation and protein–DNA binding information by Christopher E. Hart (8187)

“…In each heat-map genes are ordered by decreasing MCS score. Significant correlation can be seen between a high MCS score, protein–DNA binding and the expected expression pattern.…”

Onset of an epileptic seizure in the Stuart-Landau-like neurons population and the outcome of the controlled system. by Malbor Asllani (5537012)

“…Then we assume the coupling parameter to start to increase to eventually remain quite large, on average 0.5, in the time interval [∼ 90, ∼170]; we can observe that the SL synchronises (see inset B) while the controlled version still exhibit a non-synchronised regime (see inset D). …”

Reversible Adsorption and Interfacial Photoisomerization of Azobenzene Surfactants Studied by QCM by Maren Umlandt (9638121)

Identification of Glucose Transporters in <i>Aspergillus nidulans</i> by Thaila Fernanda dos Reis (162684)

“…The <i>ΔhxtD</i> mutant had a 7.8-fold reduction in affinity, but a 3-fold increase in the capacity for glucose uptake. …”

Characterization of the Ti Kβ spectral profile by C T Chantler (557430)

“…The peak energy of the titanium Kβ spectral profile is found to be 4931.966 ± 0.022 eV prior to instrumental broadening. This 4.5 ppm result decreases the uncertainty over the past literature by a factor of 2.6 and is 2.4 standard deviations from the previous standard. …”

Org 214007-0 does not effect rates of hepatic enzyme fluxes. by Marie-José C. van Lierop (120014)

“…<p>Mass Isotopomer Distribution Analysis (MIDA), as described in detail in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048385#s4" target="_blank">Materials and Methods</a>, was performed in mice treated p.o., once daily, for 7 days with either vehicle, prednisolone (10 mg/kg) or Org 214007-0 (1.5 mg/kg). …”

File S1 - Oligosaccharide Substrate Preferences of Human Extracellular Sulfatase Sulf2 Using Liquid Chromatography-Mass Spectrometry Based Glycomics Approaches by Yu Huang (15093)

“…<p>Contains the following files: <b>Figure S1. Normalized decreases for each HS composition assuming one sulfate removal turnover by HSulf2 from </b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105143#pone-0105143-g001" target="_blank"><b>Fig. 1</b></a><b>.…”

Longitudinal examination of morphosyntactic skills in bilingual children (Castilla-Earls et al., 2023) by Anny Castilla-Earls (10032681)

“…The average age of the children at the beginning of the study was 5;11 (years;months). A subset of the participants was identified as children with developmental language disorder (DLD, <i>n</i> = 43). …”

Supplementary Material for: Characteristics and Outcomes of Endoscopies before and during the COVID-19 Pandemic in New York by Annadurai V. (10645559)

“…<b><i>Methods:</i></b> Across 3 hospitals, we compared demographics, indications, and yield of endoscopies before and after March 16, 2020, the date on which elective procedures were canceled, as well as a recovery period for 5 months after they were resumed. …”

Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences by Vinal V. Lakhani (249536)

Disease modifying drugs in idiopathic sclerosing orbital inflammatory syndrome by Farzad Pakdel (16948)

“…<p>Idiopathic sclerosing orbital inflammatory syndrome (ISOIS) is a rare, progressive and hard to control disease. …”

Supplementary Figure 2 from MALAT1 Is Associated with Poor Response to Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients and Promotes Chemoresistance through EZH2 by Peilong Li (755143)

“…The concentration -effect curve indicated that the IC50 value of oxaliplatin for HT29 OxR cells was 10.2 μM, while the IC50 of oxaliplatin on HT29 parental cells was 1.5 μM, which means that the HT29 OxR cells was 6.8 times the ability of oxaliplatin resistance of HT29 parental cells. …”

Phase-response curves (PRCs) of the Morris-Lecar DS model for various <i>τ</i>_<i>δ</i> and <i>G</i>_in. Values of <i>G</i>_in and <i>τ</i><sub><i>δ</... by Robert P. Gowers (8735679)

“…When ( ms), increasing <i>G</i>_in switches the onset PRC shape first from a symmetric SNIC PRC (<b>A</b>) to an asymmetric HOM PRC (<b>B-C</b>), and later to a Hopf-like PRC (<b>D</b>). …”

Table_11_Dysregulation of Transcription Factor Networks Unveils Different Pathways in Human Papillomavirus 16-Positive Squamous Cell Carcinoma and Adenocarcinoma of the Uterine Cer... by Saloe Bispo (10036170)

“…Additional analysis revealed a set of MODY TFs regulated in the sequence predicted to be repressed by miR-96-5p or miR-28-3p in ADC. …”