Data_Sheet_1_Novel PANK2 Mutations in Patients With Pantothenate Kinase-Associated Neurodegeneration and the Genotype–Phenotype Correlation.PDF by Wen-Bin Li (296290)

“…In this study, we identified eight PANK2 mutations, including three novel mutations (c.1103A > G/p.D368G, c.1696C > G/p.L566V, and c.1470delC/p.R490fs494X), in seven unrelated families with PKAN. …”

Table_1_Novel PANK2 Mutations in Patients With Pantothenate Kinase-Associated Neurodegeneration and the Genotype–Phenotype Correlation.DOCX by Wen-Bin Li (296290)

“…In this study, we identified eight PANK2 mutations, including three novel mutations (c.1103A > G/p.D368G, c.1696C > G/p.L566V, and c.1470delC/p.R490fs494X), in seven unrelated families with PKAN. …”

Table_2_Novel PANK2 Mutations in Patients With Pantothenate Kinase-Associated Neurodegeneration and the Genotype–Phenotype Correlation.XLSX by Wen-Bin Li (296290)

“…In this study, we identified eight PANK2 mutations, including three novel mutations (c.1103A > G/p.D368G, c.1696C > G/p.L566V, and c.1470delC/p.R490fs494X), in seven unrelated families with PKAN. …”

Table_4_Novel PANK2 Mutations in Patients With Pantothenate Kinase-Associated Neurodegeneration and the Genotype–Phenotype Correlation.XLSX by Wen-Bin Li (296290)

“…In this study, we identified eight PANK2 mutations, including three novel mutations (c.1103A > G/p.D368G, c.1696C > G/p.L566V, and c.1470delC/p.R490fs494X), in seven unrelated families with PKAN. …”

Table_3_Novel PANK2 Mutations in Patients With Pantothenate Kinase-Associated Neurodegeneration and the Genotype–Phenotype Correlation.DOCX by Wen-Bin Li (296290)

“…In this study, we identified eight PANK2 mutations, including three novel mutations (c.1103A > G/p.D368G, c.1696C > G/p.L566V, and c.1470delC/p.R490fs494X), in seven unrelated families with PKAN. …”

Image1_Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human... by Sara Traserra (11013556)

“…The association of paracetamol (10⁻⁴ M) and hyoscine butylbromide (10⁻⁷–10⁻⁵ M) was not different from hyoscine butylbromide alone (10⁻⁷–10⁻⁵ M). …”

Table2_Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human... by Sara Traserra (11013556)

“…The association of paracetamol (10⁻⁴ M) and hyoscine butylbromide (10⁻⁷–10⁻⁵ M) was not different from hyoscine butylbromide alone (10⁻⁷–10⁻⁵ M). …”

Table1_Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human... by Sara Traserra (11013556)

“…The association of paracetamol (10⁻⁴ M) and hyoscine butylbromide (10⁻⁷–10⁻⁵ M) was not different from hyoscine butylbromide alone (10⁻⁷–10⁻⁵ M). …”

DataSheet1_Dectin-1 participates in the immune-inflammatory response to mouse Aspergillus fumigatus keratitis by modulating macrophage polarization.doc by Liu Guibo (19857723)

“…The number of macrophages in the corneal stroma of mice in the curdlan pretreatment group increased significantly compared with the PBS group, while in the laminaran pretreatment group this number decreased significantly. 5. The results of flow cytometry showed that after 3 days of mouse corneal A. fumigatus infection, the number of macrophages in the mouse A. fumigatus model in the curdlan pretreatment group was increased (10.4%) and the number of macrophages in the mouse A. fumigatus model in the laminaran pretreatment group (6.31%), when compared with the AF+FBS group (7.91%). …”

Image_1_Variations in Energy Metabolism Precede Alterations in Cardiac Structure and Function in Hypertrophic Preconditioning.PDF by Jian Wu (41301)

“…However, glut4, pdk4, mcad, pgc1α, mcd, and pparα were all decreased, while AMPK and ACC were activated in TAC 3d and returned to Sham level in De-TAC 4d, suggesting that the change in myocardial energy metabolism in HP mice was earlier than that in cardiac structure and function. …”

Table_1_Variations in Energy Metabolism Precede Alterations in Cardiac Structure and Function in Hypertrophic Preconditioning.DOCX by Jian Wu (41301)

“…However, glut4, pdk4, mcad, pgc1α, mcd, and pparα were all decreased, while AMPK and ACC were activated in TAC 3d and returned to Sham level in De-TAC 4d, suggesting that the change in myocardial energy metabolism in HP mice was earlier than that in cardiac structure and function. …”

<i>In vitro</i> dose-response and cytotoxicity of compounds against RVFV (MP12). by Elizabeth Geerling (9566942)

Parameters of proteome evolution from histograms of amino-acid sequence identities of paralogous proteins-1 by Jacob Bock Axelsen (87041)

“…Solid blue circles show the distribution of all paralogous pairs in the genome (as in Figure 1), while solid black diamonds – what is left after removing the above 5 largest families. Dashed line corresponds to a power law with the slope -4, while the solid one – the slope -5.…”

Neuronal CAPS/<i>unc-31</i> and <i>egl-21</i> function in PFT defense. by Ferdinand C. O. Los (103091)

“…<p>(A) <i>unc-31(e928)</i> and <i>egl-21(n476)</i> mutants are qualitatively hypersensitive to <i>E. coli</i>-expressed Cry5B after 48 hr exposure. …”

Treg^KIF retain their suppressive function in an <i>in vitro</i> MLR. by Elaine T. Long (367599)

“…Treg were cultured with CD3/CD28 beads with rhIL-2 for 24 hours and cultured at decreasing ratios with 1×10⁵ CFSE-labelled CD25⁻CD4⁺ effector K^b+ T cells along with (a) 3×10⁵ irradiated B10.B10S.F1 splenocytes or (b) 1×10⁵ CD3/CD28 beads. …”

Promoter methylation analysis of FGFR4 and PTPRS gene. by Constance Nebendahl (486992)

“…<p>As shown in Figure A, low birth weight (U) induced increased methylation status of FGFR4 gene in amplicons 04 (#1and #2 = −2635_−263 and −2625_−2624 and #9 = −2453_−2452) and amplicon 44 (#4 = −1046_−1045 and #5 = −1109_−1108) when related to normal birth weight animals (N). …”

Correlation of topographic and tomographic retinal imaging with functional mapping. by Peter Charbel Issa (241475)

“…<p>Threshold values of retinal sensitivity derived from microperimetry are presented according to the scale below panel i) in 2 dB steps. Normal sensitivity is indicated by green colour, and decreased sensitivity is indicated by red colour; open rectangles demonstrate absolute defects (as defined in Ref <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0012864#pone.0012864-CharbelIssa1" target="_blank">[11]</a>). …”

Normative and empirically observed estimates of incentive effects on DDM parameters. by Xiamin Leng (11883811)

“…To a lesser extent, we found a decreased threshold with higher expected rewards. …”

mRNA expression of <i>Xenopus zfp36</i> genes during development. by Karine Tréguer (103065)

“…(B) <i>In situ</i> hybridization showed that all four <i>zfp36</i> mRNA are localized at the animal pole in 4-cell stage (a–d) and morula stage (i–l) embyos. e–h correspond to histological sections from embryos shown in a–d. …”

Administration of R037 inhibits the secretion of inflammatory cytokines. by Kazushiro Takata (339569)

“…IL-17, IFN-γ and IL-10 in the culture supernatants were assayed by ELISA. Decreased IL-17 production by both dLN cells and splenocytes and decreased IFN-γ by splenocytes were observed in the R037-treated group. …”