Data_Sheet_1_Altered White Matter Integrity at Illness Onset in Adolescents With a First Episode of Psychosis.PDF by Soledad Romero (688950)

“…Anatomical images and diffusion tensor sequences were acquired using a 1.5T scanner. Whole brain, voxel-wise group differences in fractional anisotropy (FA) were investigated between participants with a FEP and controls.…”

Chronic administration of isoproterenol causes a significant transcriptional deregulation of many <i>Hdacs</i> and <i>Sirtuins</i>. by Michal Mielcarek (195209)

“…<i>Sirt 1</i> and <i>Sirt 2</i> were decreased in the hearts of WT mice, but only <i>Sirt2</i> was decreased in the hearts of R6/2 mice. …”

Image 3_Using sodium glycodeoxycholate to develop a temporary infant-like gut barrier model, in vitro.pdf by Francesca Bietto (21511316)

“…The treatment also reduced the key tight junction protein, occludin, at the cell membrane, and increased acidic mucins and extracellular alkaline phosphatase activity. Additionally, GDC decreased cAMP, suggesting its mechanism of action was via activation of a G-protein coupled receptor. …”

qPCR and immunohistochemical assessments for MIP-2. by Noriko Suzuki-Kemuriyama (3164946)

Presentation_1_HIV Disease Progression Among Antiretroviral Therapy Patients in Zimbabwe: A Multistate Markov Model.pdf by Zvifadzo Matsena Zingoni (7870622)

“…</p><p>Methods: We partitioned HIV disease progression into four transient CD4 cell counts states: state 1 (CD4 ≥ 500 cells/μl), state 2 (350 cells/μl ≤ CD4 < 500 cells/μl), state 3 (200 cells/μl ≤ CD4 < 350 cells/μl), state 4 (CD4 < 200 cells/μl), and the absorbing state death (state 5). We proposed a semiparametric time-homogenous multistate Markov model to estimate bidirectional transition rates. …”

MiRNA-miRNA interaction network in peripheral blood of patients with myocardial infarction: a gene expression meta-analysis by Setareh Zahedian (18175375)

“…Among identified miRNA-miRNA-mRNA networks miR-188-5p/miR-299-3p/natural killer cell granule protein (NKG7), miR-200a-3p/miR-199b-5p/granzyme B (GZMB), and miR-377-3p/miR-581/oviductal glycoprotein 1 (OVGP1) exhibited higher scors in terms of expression levels (>2-fold increase or decrease) and strengh of interactions (ΔG < −5). …”

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases by Rachel A. Kline (3897250)

“…This cross species comparison has generated a refined list of differentially expressed genes, including CELF5, Col5a2, PGEMN1, SNCA, Stmn1 and HOXa5, alongside a further enrichment for synaptic and axonal transcripts. …”

Image1_ASC speck serum concentrations, a component of sterile cellular inflammation, are associated with individual cardiopulmonary capacity.JPEG by Alexander Kogel (13296595)

“…Athletes with an increase in ASC speck concentrations in response to CPET had a lower peak oxygen pulse compared to those with a decrease (17.1 ± 4.2 vs. 19.8 ± 4.1, p < 0.05).…”

Table_1_Pharmacotherapy for the Treatment of Overweight and Obesity in Children, Adolescents, and Young Adults in a Large Health System in the US.DOCX by Kathryn S. Czepiel (8830901)

“…We sought to investigate current prescribing patterns of AOMs from school age through to young adulthood in a large unified health system. Using a centralized clinical data registry containing the health data of ~6.5 million patients, individuals aged 5–25 years old with overweight and obesity who were taking one of eight commonly prescribed AOMs from 2009 to 2018 were extracted. …”

Data_Sheet_1_A designed antimicrobial peptide with potential ability against methicillin resistant Staphylococcus aureus.docx by Bingqian Yuan (11787110)

“…Based on our previous research, here we designed a new antimicrobial peptide named GW18, which showed excellent antimicrobial activity against S. aureus, even MRSA, with the hemolysis less than 5%, no cytotoxicity, and no acute toxicity. …”

A new combination of naringin and trimetazidine protect kidney Mitochondria dysfunction induced by renal Ischemia / Reperfusion injury in rat by Negin Amini (12990027)

“…Forty rats were randomly allocated into five groups, harboring eight rats each: Sham, IR, NAR (100 mg/kg), TMZ (5 mg/kg) and NAR plus TMZ. …”

Bmi1 expression alters <i>in vitro</i> pancreatic cancer cell invasion and induces a chemoresistant phenotype. by Erica Proctor (379690)

“…<p>A. Overexpression of Bmi1 in MiaPaCa2 cells enhances their invasiveness in in vitro Matrigel invasion assays (left panel). …”

A TRF2 mutant lacking the N-terminus binds specifically to telomeric DNA and is inhibited by 8oxoG by Patricia L. Opresko (7493)

Data_Sheet_1_Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.docx by Dayan Sun (9555338)

“…The survival rate of the M7 haplogroup group (6.1%) was lower than that of the non-M7 haplogroup group (9.5%) after a 6-year follow-up. In cellular studies, cytoplasmic hybrid (cybrid) cells with the M7 haplogroup showed distinct mitochondrial functions from the M8 haplogroup. …”

Supplemental Materials for "Effects of maternal edible THC consumption on offspring lung growth and function in a rhesus macaque model" by Lyndsey E. Shorey-Kendrick (20510240)

“…The objective of this study was to determine whether in utero exposure to delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, is deleterious to offspring lung development and function using a rhesus macaque model. Female rhesus macaques received a daily edible containing either THC (2.5mg/7kg/day, equivalent to a heavy medical cannabis dose) or placebo during gestation and postnatally. …”

Expression of angiotensin II receptor subtypes (AT1a and AT2), atrial natriuretic peptide (ANP) and Bax in the postnatal heart. by Daniel Biermann (123780)

“…C) Cardiac ANP mRNA expression declined in both WT and KO mice during cardiac development in the postnatal period, but ANP mRNA levels remained higher in KO as compared with WT mice from postnatal day 14 on. D) mRNA expression of pro-apoptotic protein Bax is decreased in cardiac tissue of neonatal AT2 receptor knockout mice. * <i>P</i><0.05 vs. …”

ERK phosphorylation status in cytoplasmatic (A) and nuclear (B) protein fractions from PVNs of virgin, pregnant, and lactating rats. by Benjamin Jurek (322560)

Validation of qRT-PCR primers. by Heng Lian (4109116)

“…Two miR172-RT primers are designed: The miR172-RT-Primer A is fully complementary to miR172a, miR172b, and miR172e, whereas the miR172-RT-Prime C is fully complementary to miR172c and miR172d. …”

A single systemic prophylactic treatment with CpG-C results in long-term reduction of metastatic burden in the brain. by Amit Benbenishty (6524375)

“…Interestingly, in two CpG-C–treated animals, the bioluminescent signal gradually decreased and disappeared on day 21. (<b>d</b>) Ex vivo bioluminescence imaging of the brains from the syngeneic model indicated a 48-fold reduced tumor burden (total flux) in CpG-C–treated animals (<i>n</i> = 6; two-tailed unpaired Student <i>t</i> test, <i>t</i>₍₁₀₎ = 3.722, <i>p</i> = 0.0040). …”

DataSheet1_Effectiveness of Shuxuening injection in coronary heart disease: a systematic review and meta-analysis.docx by Menglong Shi (16450710)

“…<p>Background: Coronary heart disease (CHD) poses a serious threat to public health, and the current medical management still faces significant challenges. …”