Effects of Exhaustive Aerobic Exercise on Tryptophan-Kynurenine Metabolism in Trained Athletes - Fig 2 by Barbara Strasser (498431)

“…<p><b>Divergent effects of moderate vs. exhaustive physical exercise on the production of neurotransmitters:</b> Pro-inflammatory cytokines like interferon-y (IFN-y) stimulates several enzymes including [a] indoleamine 2,3-dioxygenase-1 (IDO1), which degrades tryptophan (TRP) and serotonin (5HT), [b] NADPH oxidase (NOx), which produces reactive oxygen species (ROS), and [c] GTP-cyclohydrolase-1 (GCH1), which in human macrophages forms neopterin and in other cells tetrahydrobiopterin (BH₄), the necessary cofactor of several amino acid hydroxylases, including tryptophan 5-hydroxylase (TH) for the production of 5-hydroxytryptamine (5HT, serotonin) and phenylalanine 4-hydroxylase (PAH) for the production of tyrosine, precursor of dopamine, adrenaline and noradrenaline. …”

Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques by Pingchao Li (543008)

“…Herein, we report that the magnitude and persistence of antibody and cell-mediated immunity (CMI) elicited by an Ad5-vectored COVID-19 vaccine are impaired in SIV-infected macaques with high viral loads (> 10⁵ genome copies per ml plasma, SIV^hi) but not in macaques with low viral loads (< 10⁵, SIV^low). …”

hMSC adjunctive therapy failed to alter weight loss or improve survival compared to antiviral therapy alone in experimental severe influenza. by Ilyse Darwish (446378)

“…<p>Eight-week old male C57Bl/6 mice infected with 425 EID₅₀ influenza A/PR/8 virus were administered 2.5 mg/kg oseltamivir in 100 ul ddH2O via gavage, 1×daily for 5 days, beginning day 2 P.I., with or without hMSC administration (5×10⁵ cells) on day 2 P.I. …”

Data_Sheet_1_Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese.ZIP by Ping Xu (122619)

“…<p>The effects of brewers’ spent grain (BSG) diets on the fatty liver deposition and the cecal microbial community were investigated in a total of 320 healthy 5-day-old Landes geese. …”

Data_Sheet_1_Significant Global Yield-Gap Closing Is Possible Without Increasing the Intensity of Environmentally Harmful Nitrogen Losses.docx by Andrew Smerald (12416149)

“…To do this we use the process-based, biogeochemical model LandscapeDNDC to perform global simulations on a 0.5° grid, and evaluate the response of yields and environmental N-losses to changes in N-inputs. …”

Welfare issues associated with the different treatment groups. by Sara Hestehave (4610968)

“…<p>Numbers of animals experiencing various welfare problems, with "2/30" meaning that 2 out of a total of 30 animals were affected. …”

Difference of neural activity among neurons located at recording sites with different movement thresholds for intracortical microstimulation (ICMS). by Noriyuki Higo (364990)

“…The numbers of neurons for ≤5 μA, ≤10 μA, ≤20 μA, ≤30 μA and ≤50 μA were 23, 40, 26, 22, and 22, respectively.…”

Schematics of how feedback from PIs change small GTPase profiles. by Athanasius F. M. Marée (119130)

“…<p>Shown are the Rac distributions in the 2D cell [(<b>a</b>) and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002402#pcbi.1002402.s001" target="_blank">Video S1</a>] and in a representative 1D cross-section along the cell diameter (<b>b,c</b>). …”

Table_1_The Effects of Fenugreek Extract on Growth Performance, Serum Biochemical Indexes, Immunity and NF-κB Signaling Pathway in Broiler.XLSX by Hui Huang (4122)

“…<p>In order to study the regulation of Fenugreek seed extract (FSE) on the immunity of broilers, and explore the appropriate amount of FSE in broilers' production, 1-day-old yellow feather broilers with a total of 420 birds were randomly allocated into seven treatments. …”

Tissue tropisms and fluorescence intensity of positively and negatively charged 80 nm x 320 nm hydrogel nanoparticles in <i>Anopheles gambiae</i> females following 1 and 3 day(s) o... by Cynthia C. H. Paquette (742621)

“…<i>gambiae</i> following 1 day (B) and 3 day (D) oral challenge. In mosquitoes challenged for 1 d, tissue tropisms and fluorescence intensity decreased substantially by 1 or 2 d post challenge. …”

Table_4_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

Table_1_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

Table_2_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

Table_3_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

miRNAs that are most highly regulated in proliferating CD4⁺ T cells. by Connie L. Sommers (426576)

“…<p>a. miRNAs that are increased (↑) or decreased (↓) in expression more than 5-fold relative to C57BL/6 naïve CD4⁺ T cells. miRNAs that are increased or decreased in LAT Y136F CD4⁺ T cells more than 10-fold are shown in bold. b. miRNAs that are increased (↑) or decreased (↓) in expression more than 5-fold relative to C57BL/6 memory CD4⁺ T cells.…”

Role of CTLA4 in the Proliferation and Survival of Chronic Lymphocytic Leukemia by Amit K. Mittal (440288)

“…In addition, compared to controls, the CTLA4-downregulated CLL cells showed a decreased frequency of apoptosis, which also correlated with increased expression of Bcl-2. …”

HDAC inhibitors affect tissue-specific promoters differently. by Angelika Danielsson (229695)

“…Cells were then incubated with 3 ng/ml FK228 or 5 mM VPA for 48 h. Both FK228 and VPA enhanced the transgene expression of the Ad[CgA-LUC] vector in BON cells about 10 times although the increase was not significant. …”

Terminator digest of synthetic siRNAs and vsiRNAs. by Gyorgy Szittya (251034)

“…<p>A 19mer <i>in vitro</i> synthesised and phosphorylated siRNA was digested with Terminator™ 5′-Phosphate-Dependent Exonuclease in decreasing concentration without (left panel) or after denaturation (right panel)(A). …”

Validation of experimental protocol. by Manash S. Chatterjee (240613)

“…Experiments in panels A, B, C and D were carried out with blood from the same phlebotomy. …”

Presentation_1_Phosphorylated OmpR Is Required for Type 3 Fimbriae Expression in Klebsiella pneumoniae Under Hypertonic Conditions.PDF by Tien-Huang Lin (631773)

“…Although no typical OmpR∼P binding site was found in the P_mrkA sequence, mrkA mRNA levels and P_mrkA activity were decreased in the ΔompR and ompR_D55A strains compared with the wild type (WT) strain, indicating that OmpR∼P mediates type 3 fimbriae expression at the transcriptional level. …”