SMC-specific knockout of Klf5 (smcKlf5^−/−) exacerbates the progression of Ang II–induced AAA by facilitating ROS formation. by Dong Ma (584680)

Surface tension versus time of the MHS solution (50 mM) and LNC dispersion containing 50 mM MHS as determined by drop tensiometry. by Celia R. A. Mouzouvi (4347937)

Klf5 expression is down-regulated in the ruptured human and experimental AAA. by Dong Ma (584680)

Progressive decrease in expression of Kcnj10, Kcnq1, Gjb2 and Gjb6 in <i>Spns2^tm1a/tm1a</i> mice. by Jing Chen (4762)

Klf5 down-regulation leads to human VSMC senescence. by Dong Ma (584680)

1,25D and phosphate treatment of Ocy454 cells decreases expression of genes implicated in perilacunar matrix resorption. by Ye Yuan (531126)

Islet2a morphant, but not mutant, larvae have a reduced number of dSMNs. by Rosa L. Moreno (5434796)

“…Scale bar in A, for A-C: 50 μm. (D) In tg(islet1:gfp) 72 hpf larvae, the numbers of gfp⁺ somas were reduced by injection of the Ctl MO (n = 17) and further reduced by injection of the T-MO (n = 20) compared to uninjected embryos (n = 10). ***, p<0.0001; **, p<0.0003; 8, p<0.0006; ANOVA with post-hoc Bonferroni. …”

Effect on the metabolic clearance rate (MCR) of CK under the inhibition of recombinant CYP2C9 and CYP3A4. by Jian Xiao (253329)

“…The MCRs of CK were significantly decreased compared with those of the control for CYP3A4 and CYP2C9.…”

MCP-1-deficiency decreased CD11c-expressing cells via impairing the production of ROS and decreased activation of PLCγ2, Akt, and ERK upon M-CSF stimulation in BMM. by Woon-Ki Kim (447798)

“…<p>BMMs from WT (open bar) and MCP-1-KO mice (oblique-lined bar) were incubated in the presence of M-CSF (30 ng/ml) with U73122 (10 µM), Akt inhibitor IV (0.3 µM), PD098059 (5 µM), DPI (50 nM), NAC (3 mM), or H₂O₂ (300 µM) for 4 d (A). *, <i>P</i><0.05; ***, <i>P</i><0.001 compared with vehicle-treated WT cells. …”

Absence of neocortex is associated with a dorsal shift of piriform cortex in <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

SgG2 increases NGF-dependent axonal growth. by Jorge Rubén Cabrera (685511)

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

“…Compound <b>19</b> displays antitumor activity in an AML tumor model and was also shown to decrease Foxp3 transcript levels in a dose dependent manner.…”

Growth disadvantage conferred by RecA D112R. by Irina V. Bakhlanova (2636080)

Subjects:

IL-17A promotes the expression of osteoclast-related genes involved in osteoclastogenesis. by Hao Tang (44155)

IL-17A promotes OCP autophagy through the ERK/mTOR/Beclin1 pathway induced by RANKL. by Hao Tang (44155)

Mean reaction times in ms to select the infant or the adult target (± SEM). by Sarah K. C. Holtfrerich (3353693)

Adaptation of SARS-CoV-2_Engl2 to VeroE6 and selection of decreased RDV sensitivity. by Agnieszka M. Szemiel (10196243)

IL-17A promotes RANKL-stimulated osteoclastogenesis. by Hao Tang (44155)

Inhibition of autophagy attenuates IL-17A-mediated osteoclastogenesis. by Hao Tang (44155)

Image_1_Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3).JPEG by Vania A. Figueroa (8332773)