Development and characterization of MPL36 mutants. by Weinan Zhu (1640407)

GTPCH-1 overexpression (GTPCH-1 OE) in endothelial cells (ECs) decreased LDH activity and increased NO production, tetrahydrobiopterin, and the ratio of eNOS dimer/monomer in the p... by Thorsten M. Leucker (435692)

<i>Sox17</i> mutants exhibit a failure in emVE dispersal. by Manuel Viotti (27396)

“…(A′–D′) Brightfield and MIPs of EHF stage <i>Sox17</i>^{−<i>/</i>−}<i>; Afp::GFP^Tg/+</i> embryo. …”

Fig 2 - by Tachpon Techarang (12295244)

Effect of BM pretreatment on CYP3A at mRNA and functional activity level. by Rajbir Singh (451210)

“…BM treatment decreases the mRNA levels of CYP3A1and CYP3A2 in liver and intestine as assessed by real-time PCR as described in Materials and Methods. …”

LRRK2-KO neurites show increased motility and those from LRRK2-WT^OE and LRRK2-G2019S^OE show decreased motility on PLL. by Bryan Sepulveda (408810)

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Effect of Curcumin on Serum Urate in Asymptomatic Hyperuricemia: A Randomized Placebo-Controlled Trial by Pannipa Bupparenoo (8855129)

“…Curcumin inhibits xanthine oxidase and increases uricosuric activity and, as a result, decreases serum urate (SU). This randomized controlled trial aimed to determine the effects of curcumin versus placebo on SU in subjects with asymptomatic hyperuricemia (SU level ≥ 6 mg/dL in women or ≥ 7 mg/dL in men).…”

Difference in 3 month growth outcomes by treatment arm stratified by pathogen detection at 6 and 12 months of age. by Godfrey Guga (12152390)

Knockdown of CN-A attenuate the protein synthesis inhibition under ER stress. by Mariana Bollo (244365)

“…Note that CN is decreased by the CN-A morpholinos treatment only after ER stress (lane M-tg 6). …”

Test apparatus. by Sara Hintze (3216885)

A list of the genes that are significantly downregulated or upregulated in <i>Gpdh1</i>^{<i>A10/B18</i>}<i>; Ldh</i>^<i>16/17</i> double mutant larvae relative to... by Madhulika Rai (4352803)

Fig 2 - by Atikarn Janthongkaw (17020498)

Quantitative structure–toxicity relationship models for predication of toxicity of ionic liquids toward leukemia rat cell line IPC-81 based on index of ideality of correlation by Shahin Ahmadi (9334861)

“…The outliers and promoters of increase/decrease of logEC₅₀ are extracted and the mechanistic interpretation of effective descriptors for the model is also offered.Highlights</p><p>Global SMILES-based QSAR model was developed to predict the toxicity of ILs.…”

Canonical and Noncanonical Sites Determine NPT2A Binding Selectivity to NHERF1 PDZ1 by Tatyana Mamonova (753968)

“…Experimentally introduced mutation in PDZ1 (Glu43Asp and His27Asn) decreased binding to NPT2A. Conversely, introduction of Asp183Glu and Asn167His mutations in PDZ2 promoted the formation of favorable interactions yielding micromolar <i>K</i>_Ds. …”

DataSheet1_CYP2A6 and GABRA2 Gene Polymorphisms are Associated With Dexmedetomidine Drug Response.docx by Chao Fang (456315)

“…In particular, individuals with the GG genotype had a 4-fold higher risk of heart rate abnormality than carriers of the T allele (OR = 4.32, 95% CI: 1.96–9.50, p = 0.00027).…”