Supplementary Material for: A Placebo-Controlled, Randomized Trial of Enarodustat in Patients with Chronic Kidney Disease Followed by Long-Term Trial by Akizawa T. (3588626)

“…<b><i>Methods:</i></b> Erythropoiesis-stimulating agent (ESA) naïve patients (correction group) and patients on a stable dose of ESA (conversion group) were randomized to receive 2, 4, or 6 mg of enarodustat or placebo once daily for 6 weeks in a double-blind manner (Period 1) followed by 24 weeks of open enarodustat treatment to maintain their hemoglobin (Hb) levels within a target range of 10.0–12.0 g/dL in reference to a dose adjustment algorithm (Period 2). …”

Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

Quantification of Lactobacillus (L) and Acetobacter (A) in P0 pupae and pharate adults without ecdysone signalling in the fat body and haemocytes. by Catarina Nunes (3542330)

“…<p><b>(A-B)</b> When ecdysone sensitivity is decreased in fat body and haemocytes, for both bacteria types, the number of individuals with increased bacterial loads is significantly higher in pharate adults compared to L3 larvae, revealing a deficit in bacterial growth control. …”

Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

Table1_Risk of drug-induced angioedema: a pharmacovigilance study of FDA adverse event reporting system database.xlsx by Maoxia Fan (16914033)

“…Based on the individual drug reporting odds ratio (95% confidence interval) as a measure of risk signal strength, the top five drugs are as follows: lisinopril [ROR (95% CI): 46.43 (42.59–50.62)], enalapril [ROR (95% CI): 43.51 (39.88–47.46)], perindopril [ROR (95% CI): 31.17 (27.5–35.32)], alteplase [ROR (95% CI): 29.3 (26.95–31.85)], ramipril [ROR (95% CI): 20.93 (19.66–22.28)]. …”

Table2_Risk of drug-induced angioedema: a pharmacovigilance study of FDA adverse event reporting system database.xlsx by Maoxia Fan (16914033)

“…Based on the individual drug reporting odds ratio (95% confidence interval) as a measure of risk signal strength, the top five drugs are as follows: lisinopril [ROR (95% CI): 46.43 (42.59–50.62)], enalapril [ROR (95% CI): 43.51 (39.88–47.46)], perindopril [ROR (95% CI): 31.17 (27.5–35.32)], alteplase [ROR (95% CI): 29.3 (26.95–31.85)], ramipril [ROR (95% CI): 20.93 (19.66–22.28)]. …”

Table_1_A missense mutation in the Hspa8 gene encoding heat shock cognate protein 70 causes neuroaxonal dystrophy in rats.pdf by Miyuu Tanaka (1944481)

DataSheet1_Miconazole Suppresses 27-Hydroxycholesterol-induced Inflammation by Regulating Activation of Monocytic Cells to a Proinflammatory Phenotype.docx by Bo-Young Kim (516332)

DataSheet1_Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25–35.PDF by Youn Young Lee (16841628)

“…Dex administration also resulted in decreased expression of the autophagy-related microtubule-associated proteins light chain 3-II (LC3-II), p62, lysosome-associated membrane protein2 (LAMP2), and cathepsin D in Aβ_25–35 mice and OHSC with Aβ_25–35. …”

DataSheet2_Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25–35.PDF by Youn Young Lee (16841628)

“…Dex administration also resulted in decreased expression of the autophagy-related microtubule-associated proteins light chain 3-II (LC3-II), p62, lysosome-associated membrane protein2 (LAMP2), and cathepsin D in Aβ_25–35 mice and OHSC with Aβ_25–35. …”

The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in <i>Trypanosoma brucei</i> by Federico Rojas (480253)

Data_Sheet_1_A Review and Meta-Analysis of Potential Impacts of Ocean Acidification on Marine Calcifiers From the Southern Ocean.docx by Blanca Figuerola (6672572)

miR-34a mediated Nrf-2 signaling pathway was implicated in the hepatoprotective effects of H₂S. by Xinli Huang (491724)

“…<p>The injection of miR-34a mimic decreased the mRNA (A) and protein (B) levels of Nrf-2, NQO1, GST and HO-1 in the young rats in the I/R+pretreatment with NaHS group. …”

Prenatal stress increases the spontaneous rearing (A) and spontaneous locomotor activity (B) responses in young adult rats (P60). by Ismael Palacios-García (697608)

Table_1_Effects of Virtual Reality Education on Procedural Pain and Anxiety During Venipuncture in Children: A Randomized Clinical Trial.DOCX by Jung-Hee Ryu (4339798)

“…This randomized clinical trial aimed to evaluate whether pre-procedural immersive virtual reality (VR) education could decrease pain and anxiety during venipuncture procedure of children.…”

Data_Sheet_1_Long-Term Increase in Cholesterol Is Associated With Better Cognitive Function: Evidence From a Longitudinal Study.docx by Huamin Liu (6852678)

“…</p><p>Methods: A total of 4,915 participants aged ≥45 years with normal cognition in baseline were included. …”

Fraction of model calculated data points that lie outside of the 95% confidence interval of the baseline case after a parameter has been perturbed. by KyungOh Choi (606429)

A Retrospective Longitudinal Within-Subject Risk Interval Analysis of Immunoglobulin Treatment for Recurrent Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Juthaporn Cowan (825122)

Figure 7 from Activation of Cell-Intrinsic Signaling in CAR-T Cells via a Chimeric IL7R Domain by Stamatia C. Vorri (19563842)

“…<p>Single-chain proximal IL7Rα CAR-T cells have decreased <i>in vivo</i> antileukemia activity. <b>A,</b> Schematic of the xenograft model. …”