Overexpression of mC4 decreased membrane capacitance without altering overall excitability. by Ashley L. Comer (8299128)

nLTD decreases the molecular proximity between endogenous spine cofilin and F-actin by Barbara Calabrese (553229)

Disruption of FGFR1-Frs2/3 pathway decreases the number of support cells. by Kazuya Ono (513633)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

DHT increases whereas orchidectomy decreases the weight and cross sectional area of hindlimb muscles. by Young-Eun Yoo (323357)

“…<b>A:</b> In WT mice, DHT increased the GN weight by 7% (212.4±8.8 mg), whereas orchidectomy decreased it by 14% (171.4±9.0 mg) compared with control WT mice (198.4±5.5 mg). …”

Ofd1 protection of photoreceptors from oxidative stress via decreasing ROS production. by Juan Wang (115708)

“…<p>(A) The intracellular oxidant DCFH of MNU-induced ROS in 661W cells observed by green fluorescence using Leica fluorescence microscope (with monochromatic CCD), and measured using fluorometer at wavelength of 488/525 nm. …”

Insulin ICV injection (14 mU) decreases olfactory detection in fasted rats. by Pascaline Aimé (293920)

“…Post-hoc comparisons showed that insulin ICV injections significantly decreased the olfactory detection index for both ISO 10⁻⁹ and ISO 10⁻⁸ odor dilutions (SNK, compared to NaCl for each odor # p¹<0.05; n = 18) and that the olfactory detection index is higher for ISO 10⁻⁸ compared to ISO 10⁻⁹ for each ICV treatment (SNK, § p¹<0.05; n = 18) (<i>D</i>) Insulin ICV injection (14 mU) does not change locomotor activity. …”

Loss of <i>Nf1</i> increases sleep fragmentation and decreases sleep depth. by Elizabeth B. Brown (4582978)

“…<b>D</b>. There is a significant effect of genotype on sleep duration (two-way ANOVA: F_2,312 = 46.27, <i>P</i><0.0001). …”

Rho kinase (ROCK) inhibitors promote neurite elongation of human model neurons. by Frank Roloff (695802)

Multiple trauma and hemorrhagic shock induce a transcriptional immune response. by Marc-Alexander Oestreich (13961375)

Ibuprofen increased neurite length of human model neurons. by Frank Roloff (695802)

RhoA and Rho kinase inhibitors promote initiation of neurites. by Frank Roloff (695802)

Revisiting the sealed heating method–heating cells in a low volume decreases nuclear Chk1. by Andrew J. Massey (239469)

SDG decreases iron-induced oxidative stress in H9c2 cells. by Stephanie Puukila (568109)

Fitting curve of rock E₅₀. by Junxia Zhou (14381598)

<i>Mycobacterium tuberculosis</i> thymidylate synthase (ThyX) is a target for plumbagin, a natural product with antimycobacterial activity - Fig 2 by Apurba Sarkar (8399571)

Cytochalasin D decreases ENaC activity when the channel coexpressed with RhoA. by Alexey V. Karpushev (367701)

Predicted distance (km) needed to achieve a correlation coefficient of at least r =  0.50 using the median-based linear regression models. by Claire Stevens (11127729)

HSF2 regulates ORF50 expression in an RTA independent manner. by Lorenza Cutrone (21144285)

Prediction accuracy as a function of patient variation for different noise strengths. by Manuel Mai (497861)