Flow diagram of different experiments and the study process. by Omid Mehrpour (9385929)

Subjects:

Analysis of independent prognostic factors. by Yajia Chen (20685780)

Association of vitamin D3, VDR gene polymorphisms, and LL-37 with a clinical form of Chagas Disease by Luiz Roberto de Oliveira Junior (7369052)

The efflux of 6 representative isolates (A; standard strain and B, C, D, E, and F; 5 tested isolates) in the absence of the tested compounds (acridine orange only; AO, negative con... by Safaa Abdel-Aal Mohamed Abdel-Karim (13175696)

Heat map of gene expression, averaged across all samples representing each combination of factors (population and time-point). by Line K. Bay (411810)

DOT or SAT for Rifampicin-resistant tuberculosis? A non-randomized comparison in a high HIV-prevalence setting by Erika Mohr (3331566)

“…</p><p>Conclusion</p><p>The introduction of SAT during the continuation phase of RR-TB treatment does not adversely affect final RR-TB treatment outcomes in a high TB and HIV-burden setting. This differentiated, patient-centred model of care could be considered in RR-TB programmes to decrease the burden of DOT on patients and health facilities.…”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…While screening off-target effects of rigid (<i>N</i>)-methanocarba-adenosine 5′-methylamides as A₃ adenosine receptor (AR) agonists, we discovered μM binding hits at the δ-opioid receptor (DOR) and translocator protein (TSPO). …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…While screening off-target effects of rigid (<i>N</i>)-methanocarba-adenosine 5′-methylamides as A₃ adenosine receptor (AR) agonists, we discovered μM binding hits at the δ-opioid receptor (DOR) and translocator protein (TSPO). …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…While screening off-target effects of rigid (<i>N</i>)-methanocarba-adenosine 5′-methylamides as A₃ adenosine receptor (AR) agonists, we discovered μM binding hits at the δ-opioid receptor (DOR) and translocator protein (TSPO). …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…While screening off-target effects of rigid (<i>N</i>)-methanocarba-adenosine 5′-methylamides as A₃ adenosine receptor (AR) agonists, we discovered μM binding hits at the δ-opioid receptor (DOR) and translocator protein (TSPO). …”

Even a Chronic Mild Hyperglycemia Affects Membrane Fluidity and Lipoperoxidation in Placental Mitochondria in Wistar Rats - Fig 6 by María del Consuelo Figueroa-García (832711)

Bald thigh syndrome in sighthounds—Revisiting the cause of a well-known disease by Magdalena A. T. Brunner (4532341)

“…Further research is required to clarify whether the <i>IGFBP5</i> variant represents a predisposing genetic risk factor. …”

Effects of cathode and anode of the direct current on changes in palmar grip strength: assessment through a dynamometry by Hernán Andrés de la Barra Ortiz (5084759)

Comparison of the time course of the SARS-CoV-2 pandemic up to 7 November 2020 for the seven regions in England for the time-varying IFR model between using death within 28 days of... by Siyu Chen (278663)

Stress-sensitive antidepressant-like effects of ketamine in the mouse forced swim test by Paul J. Fitzgerald (3239337)

“…This combination of fast action and a therapeutic effect that lasts far beyond the drug’s half-life points to a unique mechanism of action. …”

Synthesis, Crystal Structure, and Spectroscopic Characterization of a Series of Cubane-like Mo−Sb Clusters Containing a [Mo₃SbOS₃]⁷⁺ Core by Shao-Fang Lu (2974926)

“…Crystal data:  <b>1</b>, triclinic, <i>P</i>-1, <i>a</i> = 11.746(4) Å, <i>b</i> = 12.462(3) Å, <i>c</i> = 17.851(6) Å, α = 73.54(2)°, β = 75.06(3)°, γ = 88.11(3)°, <i>V</i> = 2419(3) ų, <i>Z</i> = 2, 4253 reflections, <i>R</i> = 0.055; <b>2</b>, triclinic, <i>P</i>-1, <i>a</i> = 12.76(1) Å, <i>b</i> = 17.86(1) Å, <i>c</i> = 11.882(4) Å, α = 75.05(4)°, β = 88.15(7)°, γ = 73.24(4)°, <i>V</i> = 2502(6) ų, <i>Z</i> = 2, 1849 reflections, <i>R</i> = 0.086; <b>3</b>, triclinic, <i>P</i>-1, <i>a</i> = 11.727(4) Å, <i>b</i> = 12.951(3) Å, <i>c</i> = 17.957(4) Å, α = 73.52(3)°, β = 76.22(3)°, γ = 89.00(2)°, <i>V</i> = 2536(3) ų, <i>Z</i> = 2, 6306 reflections, <i>R</i> = 0.053; <b>5</b>, triclinic, <i>P</i>-1, <i>a</i> = 13.261(4) Å, <i>b</i> = 13.529(4) Å, <i>c</i> = 12.535(8) Å, α = 101.54(3)°, β = 105.13(4)°, γ = 93.20(2)°, <i>V</i> = 2113(2) ų, <i>Z</i> = 2, 4104 reflections, <i>R</i> = 0.060.…”

A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country by Zaghloul, Nancy

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The effect of normobaric oxygen in patients with acute stroke: a systematic review and meta-analysis by Jiayue Ding (4689559)

“…Compared to controls, there was a minor trend toward NBO benefits in short-term prognostic indices, as indicated by decreased ΔNIHSS at our defined time points. …”

Photographs of the left eye 5 years (A–D) and 8 years (E) after systemic corticosteroid therapy in a patient shown in Fig 2. by Saho Saito (731215)

Image_5_Thermal preconditioning in a reef-building coral alleviates oxidative damage through a BI-1-mediated antioxidant response.jpeg by Eva Majerová (13895703)