A Recyclable, Immobilized Analogue of Benzotetramisole for Catalytic Enantioselective Domino Michael Addition/Cyclization Reactions in Batch and Flow by Javier Izquierdo (1333773)

“…A polystyrene-supported, enantiopure benzotetramisole (BTM) analogue (<b>5</b>) has been synthesized from (2<i>S</i>,3<i>S</i>)-phenylglycidol through a five-step sequence involving a copper-catalyzed alkyne azide cycloaddition (CuAAC) reaction as the final, immobilization step. …”

BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells by Ana Rita Thomazela Machado (6047777)

“…In co-culture, 1.00 and 5.00 μg/mL induced cytotoxicity (p < 0.05). BjussuLAAO-II increased the methylation of CCND1 and decreased the methylation of CDKN1A in monoculture and GADD45A in both cell-culture models (p < 0.05). …”

DataSheet_1_Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet.csv by Ana Ramos-Levi (724988)

“…In CAU, variants rs4402960, rs7651090, IGF2BP2; rs1387153, rs10830963, MTNR1B; rs17676067, GLP2R; rs1371614, DPYSL5; rs5215, KCNJ1; and rs2293941, PDX1 were significantly associated with an increased risk of GDM, whilst rs780094, GCKR; rs7607980, COBLL1; rs3746750, SLC17A9; rs6048205, FOXA2; rs7041847, rs7034200, rs10814916, GLIS3; rs3783347, WARS; and rs1805087, MTR, were significantly associated with a decreased risk of GDM, In HIS, variants significantly associated with increased risk of GDM were rs9368222, CDKAL1; rs2302593, GIPR; rs10885122, ADRA2A; rs1387153, MTNR1B; rs737288, BACE2; rs1371614, DPYSL5; and rs2293941, PDX1, whilst rs340874, PROX1; rs2943634, IRS1; rs7041847, GLIS3; rs780094, GCKR; rs563694, G6PC2; and rs11605924, CRY2 were significantly associated with decreased risk for GDM.…”

Neuroprotective body hypothermia among newborns with hypoxic ischemic encephalopathy: three-year experience in a tertiary university hospital. A retrospective observational study by Mauricio Magalhães (10445366)

“…Studies have shown that therapeutic hypothermia decreases neurological sequelae and death. Our aim was therefore to report on a three-year experience of therapeutic hypothermia among asphyxiated newborns.DESIGN AND SETTING:Retrospective study, conducted in a university hospital.METHODS:Thirty-five patients with perinatal asphyxia undergoing body cooling between May 2009 and November 2012 were evaluated.RESULTS:Thirty-nine infants fulfilled the hypothermia protocol criteria. …”

Venn diagram showing the number of operational taxonomic units (OTUs) unique to each region and shared between the regions (North, Central, and South) using a random subsample of n... by Rodrigo Villalobos (4566694)

BmSUH is a membrane-associated midgut protein. by Yanting Liang (10677417)

Effects of tumor necrosis factor inhibitors and tocilizumab on the glycosylated hemoglobin levels in patients with rheumatoid arthritis; an observational study by Yukimi Otsuka (5142788)

“…Our study suggests that TCZ decreases the HbA1c levels in RA patients to a greater extent than TNFi.…”

Comparison of DRM subunit chromatin localization in wild-type and <i>lin-35</i> null late embryos. by Paul D. Goetsch (4559587)

“…<p>(A) Heatmap of normalized ChIP-seq profiles of pooled replicates for each DRM subunit sorted from highest to lowest signal in the following classes. …”

Table_1_The role of miR-10a-5p in LPS-induced inhibition of progesterone synthesis in goose granulosa cells by down-regulating CYP11A1.XLSX by Xinyi Guo (3755509)

“…We also determined that the downregulation of miR-10a-5p led to CYP11A1 expression. Overexpression of miR-10a-5p suppressed LPS-induced CYP11A1 expression, resulting in decreased progesterone secretion. …”

Cooperativity increases with receptor density. by Stephan Eismann (835052)

Non-cytotoxic levels of propofol decrease LPS-induced ROS generation, which ROS is required for LPS-induced activation of Akt and NF-κB as well as NO generation. by Chung-Hsi Hsing (355049)

Table_1_Milled rapeseeds and oats decrease milk saturated fatty acids and ruminal methane emissions in dairy cows without changes in product sensory quality.docx by Anni Halmemies-Beauchet-Filleau (14683582)

“…The milk fat saturated FAs were decreased by 16%–20% in the test diet, mainly due to the de novo FAs of 6- to 16-carbons (a reduction of 22%–48%). …”

Ldb2a complexes suppress positive feedback while activating negative feedback for TGFβ family signalling. by Wenchao Gu (344453)

“…<p>(A) ChIP-qPCR analysis detected an enrichment of Ldb2a at the promoter of <i>Smad7</i> (15-fold) and the promoter of <i>Sqt</i> (5-fold) at the shield stage. …”

Acquisition of Mutant scFv With a Higher Affinity against Wild-type, Beta and Delta SARS-CoV-2 using a HEK 293T Antibody Surface Display Library. by Ye Yang (297214)

Cortisone (500 nM, 24 h, black) and cortisol (500 nM, 24 h, dark grey) decrease lipogenesis in differentiated Chub-S7 cells. by Laura L. Gathercole (341979)

Data_Sheet_5_Efficacy and Safety of Resistance Training for Coronary Heart Disease Rehabilitation: A Systematic Review of Randomized Controlled Trials.docx by Yixuan Fan (8782853)

Prevalence of deleterious hearing loss (A) based on CTCAEv4.03 ≥grade 2, Muenster ≥grade 2b, SIOP ≥grade 2, Brock ≥grade 2 and Chang ≥grade 2a, and ototoxicity grade distribution (... by E. Clemens (6335312)

Nile tilapia nursery feeding management in a biofloc system by Bruno Corrêa da Silva (4642855)

“…On the other hand, low feeding rates cause a decrease in the growth and uniformity of the tilapia juveniles. …”

Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P₂ by Kiyomi Nigorikawa (340973)

“…Inpp4a was recruited to the phagosome membrane by a mechanism other than the direct interaction with Rab5. …”

Numerical value for graphs Figs 3 and 5. by Attarat Pattanawongsa (497928)