DataSheet_1_Dual targeting of glutamine and serine metabolism in acute myeloid leukemia.pdf by Kanwal M. Hameed (18386853)

“…Rylaze-BI4916 treatment in AML cell lines led to the inhibition of cap-dependent mRNA translation and protein synthesis, as well as a marked decrease in intracellular glutathione levels, a critical cellular antioxidant. …”

Prevalence of self-referred chronic pain and intercurrences in the health of the elderly by Ezequiel Vitório Lini (5255471)

“…CONCLUSION: Measures to decrease chronic pain in the elderly should be priority, especially in primary health attention services, because this is a multidimensional and complex public health problem.…”

Inhibiting S6K1 does not alter pFMRP S499 levels <i>in vivo</i>. by Christopher M. Bartley (560971)

“…(<b>C</b>) Quantification verifies a significant decrease in pS6:S6 but no change in pFMRP:FMRP following mTORC1 or S6K1 inhibition <i>in vivo</i>. …”

Comparison between selecting mt protein-coding (PC) genes by individual gene performance vs. by length. by Justin C. Havird (507301)

“…<p>Utilizing the three mt protein-coding (PC) genes that individually performed “best” (based on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084080#pone-0084080-g003" target="_blank">Figure 3:</a> ND5, ND4, ND2), rather than the three longest (i.e, ND5, COX1, and ND4) mt PC genes, resulted in a significantly lower decrease in Ln <i>L</i> (± S.E.M.) compared to the “supergene” (i.e., all 13 mt PC genes) topology (<i>t</i>-test, <i>t</i> = 2.21, <i>df</i> = 1, 66, <i>P</i> = 0.03). …”

Characterization of urinary exosomes. by Tim Lange (2385133)

“…Zetasizer analysis of urinary exosome samples (C). The results of the 5 measurements of the urine sample displayed in TEM (A) are shown (C, a). …”

Endocytosed albumin co-localized with lysosomes and was degraded in podocytes. by John M. Carson (577297)

“…<p>Confocal microscopy image demonstrating co-localization of albumin and lysosomes in a podocyte treated with 1.5 mg/mL FITC-albumin and Cathepsin B Magic Red for 1 hour. …”

Activated carbon loaded with manganese and iron for glyphosate adsorption: Kinetics, isotherms and thermodynamic studies by Natalia Ueda Yamaguchi (6722057)

“…Adsorption isotherm experiments were carried out at 5, 15, 25, 35 and 45°C. The adsorption isotherms presented a better fitting using the Freundlich model (R2>0.98), indicating a multilayer adsorption of glyphosate. …”

OCT imaging during ON in MOG^TCRxThy1CFP mice by Katie Lidster (479714)

“…<p>(A) Histological changes in the thickness of RGC layer in control mice (n=5) and MOG^TCRxThy1CFP mice (n=5) at day 21. …”

Kinetics of PfR6 interaction with HMG-box. by Diego F. Joseph (6569912)

“…Mixing the labeled protein with the probe-bound aptamer (green) resulted in a decrease of fluorescence over time, indicating that the binding of both components results in the quenching of fluorescein due to its vicinity with the quencher in the protein. …”

Simulation of [Mg²⁺]_i–mediated changes of junctional conductance (black traces) measured in RIN cells expressing Cx36. by Mindaugas Snipas (3909556)

“…The fitted junctional conductance (g_j) kinetics (red trace) was obtained at ~4.5-fold V₀ increase and ~1000-fold p_c1→c2 decrease. …”

The Effect of p38MAPK on Cyclic Stretch in Human Facial Hypertrophic Scar Fibroblast Differentiation by Qi-cui Du (468638)

“…The fibroblasts were synchronized and randomly assigned to two groups: cyclic stretch and cyclic stretch pre-treated with SB203580 (a p38MAPK inhibitor). Cyclic stretch at 10% strain was applied at a loading frequency of 10 cycles per minute (i.e. 5 seconds of tension and 5 seconds of relaxation) for 0 h, 6 h and 12 h. …”

Kupffer cell populations. by Ivan Linares (5059373)

“…<p>Flow-cytometry analysis showed a significant decrease on pro-inflammatory NO+ KCs population in RGZ vs CTRL group since 1hr (28.49±4.99 vs 53.54±9.15%; p = 0.040), this difference further increase at 6hr (5.51±0.54 vs 31.12±9.58%; p = 0.009) and 24hr (4.15±1.50 vs 17.10±4.77%; p = 0.043) following reperfusion (A). …”

Homozygous <i>mray</i> mutants show severe craniofacial malformations starting early in development. by Adam P. Ross (437534)

“…<p><b>A, B,</b> Fluorescent images of a wild-type embryo compared to a homozygous <i>mray</i> littermate at E12.5. …”

OVA-specific cytokine production and proliferation of splenic lymphocytes. by Carolin Boehne (10531245)

“…<p>(A-C) Production of IL-5 (A), IL-10 (B) and IL-13 (C) in cell culture supernatants of spleens showed a significant decrease after tolerization compared to allergic (<i>OVA</i>) animals in both, WT and Tim-3^-/- mice. …”

Data_Sheet_1_Constitutionally High Serotonin Tone Favors Obesity: Study on Rat Sublines With Altered Serotonin Homeostasis.PDF by Maja Kesić (8620716)

“…<p>Central and peripheral pools of biogenic monoamine serotonin (5-hydroxytryptamine [5HT]) exert opposite effects on the body weight regulation: increase in brain 5HT activity is expected to decrease body weight, whereas increase in peripheral 5HT activity will increase body weight and adiposity. …”

Hh ligands produced by tumor cells impacts the osteoblast differentiation and expression of RANKL and PTHrP. by Shamik Das (174657)

“…Addition of the Hh neutralizing antibody, 5E1, caused a reduction in ALP activity. SUM1315+5E1 (∧p = 0.014); MDA-MB-231+5E1 (p = 0.12), SUM159+5E1 (∧p = 0.04), MDA-MB-435+5E1 (p = 0.6). …”

Summary of <i>CHL1</i> expression in 11 tumor types as measured with the Clontech Cancer Profiling Arrays I and II. by Vera N. Senchenko (53211)

Supplementary Material for: Maternal Thinness and Obesity and Customized Fetal Weight Charts by GonzálezGonzález N.L. (11288730)

“…<b><i>Conclusion:</i></b> The use of CC_(18.5–25) allows a more accurate identification of LGA and SGA infants at risk of perinatal morbidity than conventional CC. …”

Polyethersulfone hollow fiber membranes: effect of the internal liquid and the addition of clay by Rodholfo da Silva Barbosa Ferreira (6721565)

“…From the flow measurements it was possible to observe that the membrane containing 5% CLNa with the presence of the solvent in the internal liquid obtained a greater flow over time, this occurred due to the presented more uniform morphology of the membrane.…”

Feeding effects of cottonseed and its co-products on the meat proteome from ram lambs by Tiago do Prado Paim (5671568)

“…The effect of gossypol (a compound present in cotton co-products) in ruminant metabolism and meat quality is not yet clear. …”