Graphical summary of differential sense and antisense expression (DE) in Rho⁺ and Δ<i>rho</i> across strands and growth phases. by Vladimir Bidnenko (4258573)

<i>Vps13</i> mutant flies show a decreased life span, age dependent impairment of locomotor function and neurodegeneration. by Jan J. Vonk (3686662)

LiCl administered via 0.5% LiCl food pellets for 4 wks decreases the antioxidant stress response. by Christine M. LaPash Daniels (796881)

“…<p>(A) LiCl decreases <i>Nrf2</i> transcripts in hippocampus and cortex of R236H/+ mice (N = 5 male mice per group). …”

Missense Variant in MAPK Inactivator <i>PTPN5</i> Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring by Ravi F. Sood (263139)

“…</p><p>Results</p><p>Our study population consisted of 538 adults (median age 40 years) who were predominantly White (76%) males (71%) admitted to our center from 2007–2014 with small-to-moderate-sized burns (median burn size 6% total body surface area). Of 2,146 SNPs tested, a rare missense variant in the <i>PTPN5</i> gene (rs56234898; minor allele frequency 1.5%) was significantly associated with decreased severity of post-burn HTS (<i>P</i> = 1.3×10⁻⁶). …”

Panel probit models: Dummy variable which takes a value of 1 for a top 5 publication. by Sergey V. Popov (6719075)

Theme 5 results—mortality. by Corey J. A. Bradshaw (8032406)

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa by Andrej Emanuel Cotman (5203904)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”

Mutation of Ser-473 in GC-A to alanine but not glutamate decreases ANP-stimulated guanylyl cyclase activity. by Andrea R. Yoder (165684)

Decrease of cell viability and alterations of cell membrane permeability by infection with rotavirus isolates. by Carlos A. Guerrero (1264551)

Data for Figs 1A–1I, 2A–2J, 3B–3H, 4A–4L, 5A–5C, 6A–6C, 6E, by Xiaohua Zhang (350570)

Unadjusted associations between breastfeeding exclusivity and CD8+ T cell numbers at 6 months. by Michelle A. E. Jansen (740955)

Adjusted associations between breastfeeding and cell numbers at 6 and 14 months. by Michelle A. E. Jansen (740955)

Adjusted associations between breastfeeding and memory B- and T-cell subsets at 6 months. by Michelle A. E. Jansen (740955)

Adjusted associations between breastfeeding exclusivity and CD8+T cell numbers at 6 months. by Michelle A. E. Jansen (740955)

Schematic illustration of the prediction model for all the five vignettes. by Michelle Dey (525235)

Impact of breastfeeding duration on T-lymphocyte subsets at 6 months of age. by Michelle A. E. Jansen (740955)

Suppression of the growth defects in flippase mutants by decreased synthesis of PI. by Kanako Yamagami (703555)

<i>Oenocarpus bacaba</i> palm tree (A) and fruit (B). by Eudes Alves Simões-Neto (19697968)

“…Its spread to non-endemic areas has made it a global health issue. The aim of this work is to demonstrate the difficulties encountered in handling a real-life situation.…”