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dna decrease » _ decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a dna » _ dna (Expand Search), b dna (Expand Search), i dna (Expand Search)
dna decrease » _ decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a dna » _ dna (Expand Search), b dna (Expand Search), i dna (Expand Search)
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Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey
Published 2013“…Univariate sensitivity analysis highlighted that increasing the duration of voriconazole by >1.2 days or decreasing LAmB by >1.0 days changes the result. Monte Carlo Simulation resulted in 69.4% of simulations favouring voriconazole per patient treated.Conclusion: There is a strong likelihood that voriconazole is economically more favourable than LAmB in the empiric treatment of IFI in Turkey.…”
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688
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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…We anticipate that mutations affecting conserved residues or cofactor binding sites will lead to pronounced disruptions in enzymatic activity and protein stability and allow us to elucidate the underlying molecular mechanisms of disease pathogenesis for each CBS-associated missense mutation. Utilizing a multidisciplinary approach, including site-directed mutagenesis and DNA cloning, recombinant protein expression, affinity chromatography purification, circular dichroism spectroscopy, enzymatic assays, and in silico modeling, we assessed the impact of these mutations on CBS stability and function. …”
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690
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The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.
Published 2020“…One hundred and fifty warfarin-treated Qatari patients on a stable dose and with a therapeutic INR for at least three consecutive clinic visits were recruited. …”
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694
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