The consequences of STAT and SMAD downregulation on FA gene expression in HeLa cells. by Daniel Meier (346896)

“…<p>(<b>A</b>) The strongly reduced mRNA expression of <i>FANCA, -B, -C, -E and -L</i> following <i>STAT1</i> knockdown in the respective FANC gene (<i>FANCA</i>, <i>-B</i>, <i>-C</i>, <i>-E</i>, <i>-F</i>, <i>-G</i>, <i>-L</i> and <i>M</i> correspond to lanes 1–8, respectively). …”

Topological changes of the Gαs protein upon β₂AR binding. by Min Hyeok Kim (2071243)

“…The distance between the α5 helix and α4-β6 decreases to 7 Å, which is within the interaction range. …”

Improved control of blood pressure and albuminuria among patients with type-2 diabetes in Finnish open care by Juha Varis (2746075)

“…This calls for good care of patient with diabetes with a focus on hypertension. Patient data were collected from 42 Finnish primary care centres. …”

Capsaicin inhibited the growth of human SCLC tumors <i>in vivo</i>. by Kathleen C. Brown (365508)

“…(F) Western blotting of tumor lysates from mice showed that capsaicin treatment decreased the expression of E2F-responsive proliferative genes namely cyclin E, TS, cdc25A and cdc6. β-actin was used as the loading control for the western blotting experiments. …”

The dynamic causal models compared using Bayesian model selection (model space). by Josh Kahan (291836)

“…Positive B-matrix parameters (value in green) represent an increased target response to input (i.e. an increased gain), whereas negative values indicate a decreased target response to input (i.e. a reduced gain). …”

Chronic EtOH exposure alters prefrontal neurotrophin levels. by Gina M. Fernandez (2547475)

“…(B) Mean concentration levels (pg/mg) for β-NGF in the prefrontal cortex by Age and Treatment group, collapsed across time-points. There was a main effect of Treatment [E, p<0.05], with CET rats displaying significantly decreased levels of β-NGF in the prefrontal cortex. …”

The MTE posits that temperature constrains rates of metabolic processes within cells, and these constraints emerge at higher levels of biological organization, such as individuals,... by Mary I. O’Connor (5047526)

“…<p>Within individuals, constraints imposed by temperature on cellular respiration and associated biological processes (A) can be estimated as the exponential increase of metabolic rate over a temperature gradient (described by the activation energy parameter <i>E</i>_<i>a</i>). …”

Import risk aggregated on regional level “to target” vs. “from source” and its geodesic distance dependence. by Pascal P. Klamser (10305732)

“…The fitted exponent <i>α</i> of the import risk to a single target decreases with the respective regional WAN flow out of the target region (<b>F</b>), i.e. the more connected a region, the weaker the import risk decays with distance. …”

Intracellular ROS levels in melanoma cells and melanocytes determined by DCFH-DA assay. by Irene L. Ibañez (137874)

“…<p>(A–D) Intracellular ROS levels decreased in melanoma cells either when treated with catalase or when overexpressing it. …”

The impact of stressor exposure on the commensal flora. by Thomas Maslanik (295204)

“…<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050636#pone-0050636-g005" target="_blank">Figure 5A</a> depicts the relative abundance of <i>Prevotella</i> decreased in fecal samples immediately following termination of the stressor. …”

Table_2_Reduced NK Cell Cytotoxicity by Papillomatosis-Derived TGF-β Contributing to Low-Risk HPV Persistence in JORRP Patients.docx by Xunyao Wu (12208700)

“…Finally, RT-PCR analysis show that both HPV6-E6-E7 and HPV11-E6-E7 overexpression leads to higher TGFB1 expression compared with control SNU-1076 cell line, and higher CXCR6 expression is detected on NK coculture with HPV11-E6-E7-overexpressing cells. …”

Table_1_Reduced NK Cell Cytotoxicity by Papillomatosis-Derived TGF-β Contributing to Low-Risk HPV Persistence in JORRP Patients.docx by Xunyao Wu (12208700)

“…Finally, RT-PCR analysis show that both HPV6-E6-E7 and HPV11-E6-E7 overexpression leads to higher TGFB1 expression compared with control SNU-1076 cell line, and higher CXCR6 expression is detected on NK coculture with HPV11-E6-E7-overexpressing cells. …”

Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease by Michael R. Heaven (2812981)

“…Alexander disease (AxD) is a neurodegenerative disorder characterized by astrocytic protein aggregates called Rosenthal fibers (RFs). …”

Effector cytokine potential is acquired alongside CD200R expression in vivo. by Stefano Caserta (173252)

“…A. Infection with <i>S. mansoni</i> (8wk) increased CD200R⁺ IL-4⁺ CD4 cells in MesLN from 0.017±0.019% to 3.39±1.36% and 83±4.14% of IL-4⁺ cells were CD200R⁺, while CD200R^– TNFα⁺ CD4 cells decreased from 47.5±4.66% to 30.0±0.99%. …”

Suitability of different levels of sunflower cake from biodiesel production as feed ingredient for lamb production by Lidiane Fagundes da Silva Monteiro (10446558)

“…A control diet without SFC was compared with diets containing 5, 10, and 15% of dietary dry matter (DM) of SFC replacing soybean meal and corn. …”

Table 1_Effect of propinox and pinaverium bromide on ex vivo colonic motor patterns and their synergistic effect with hyoscine butyl bromide.docx by Sara Traserra (11013556)

“…EFS-induced contractions were slightly decreased by pinaverium bromide (10^–5 M; circular muscle: 39% reduction, but no effect on longitudinal muscle) and propinox (10^–5 M: circular 48% and longitudinal 37%), and to a greater extent, by the combination with HBB. …”

Suppressed miRNAs identified by RNA sequencing analysis both cytoplasm and whole cell using qPCR with normalization of weighted cDNA templates. by Lingzhi She (11981756)

“…<p>qPCR analysis showed that the expression of 6 out of the top 15 downregulated DE miRNAs was decreased in whole-cell samples (left panel, two-sided t test, W-: n = 4, W+: n = 4, aae-miR-9a: <i>P</i> = 0.0043, aae-miR-281-5p: <i>P</i> = 0.0010, aae-miR-252-5p: <i>P</i> = 0.0449, aae-miR-2a-3p: <i>P</i> = 0.0192, aae-miR-12-5p: <i>P</i> = 0.0089, aae-miR-1175-5p: <i>P</i> = 2.1435×10⁻⁶) and cytoplasm samples (right panel, two-sided t test, W-: n = 3, W+: n = 3, aae-miR-9a: <i>P</i> = 0.0130, aae-miR-281-5p: <i>P</i> = 0.0005, aae-miR-252-5p: <i>P</i> = 0.0087, aae-miR-2a-3p: <i>P</i> = 0.0058, aae-miR-12-5p: <i>P</i> = 0.0002, aae-miR-1175-5p: <i>P</i> = 0.0033) from W+ cells in small RNA sequencing. …”

DLK inhibition on low dose nocodazole treatment impacts gene expression. by Laura DeVault (798362)

“…E) Cell compartment enrichment in cell cortex (GO:0005938, FDR 0.28243, p = 0.0057389), neuron projection terminus (GO:0044306, FDR 0.46809, p = 0.006) F) Molecular function enrichment in DNA-binding Transcription Activator Activity increased after nocodazole treatment in a DLK-dependent manner (NES: -2.0360, FDR: 0.043388, GO:0001228, p = 0.003). …”

Table_1_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.docx by Thomas Kjeld (5685143)

“…</p><p>Results: During pool apnea of maximum duration (385 ± 70 s), SAT decreased from 99.6 ± 0.5 to 58.5 ± 5.5% (∼PaO₂ 4.8 ± 1.5 kPa, P < 0.001), while Glu increased from 5.8 ± 0.2 to 6.2 ± 0.2 mmol/l (P = 0.009). …”

Data_Sheet_2_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.zip by Thomas Kjeld (5685143)

“…</p><p>Results: During pool apnea of maximum duration (385 ± 70 s), SAT decreased from 99.6 ± 0.5 to 58.5 ± 5.5% (∼PaO₂ 4.8 ± 1.5 kPa, P < 0.001), while Glu increased from 5.8 ± 0.2 to 6.2 ± 0.2 mmol/l (P = 0.009). …”