Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

TG6-44 treatment decreases IFN-β levels in A/X31-infected THP-1 cells. by Juan A. De La Cruz (11154187)

GFP expression decreases upon differentiation towards pancreatic progenitor cells. by Nicole A. J. Krentz (669397)

Choroidal Neovascularization Is Inhibited in Splenic-Denervated or Splenectomized Mice with a Concomitant Decrease in Intraocular Macrophage by Xue Tan (2994324)

Effects of decreased NSUN2 and METTL1 expression on 5-FU-treatment and heat stress and 5-FU. by Mayumi Okamoto (280005)

Inhibition of RecA-mediated and DNA-dependent ATP hydrolysis by RecX proteins. by Irina V. Bakhlanova (2636080)

cGAS inhibition decreases ISG RNA in H358 cells. by Lorellin A. Durnell-Bettis (22656332)

Inhibition of RecA-mediated ATP hydrolysis by RecX proteins during DNA strand exchange. by Irina V. Bakhlanova (2636080)

Decrease in the operational range of the enzymatic controller of Fig 51 (in dual-E control mode) as a function to decreased values of the forward enzymatic rate constants <i>k</i>₉, <i>k</i>₁₁, <i>k</i>₁₃, and <i>k</i>₁₅. by Qaiser Waheed (5095328)

Effects of RecX proteins on the growth curves of cells expressing wild type RecA protein or RecA D112R protein. by Irina V. Bakhlanova (2636080)

Supplementary Material for: Anti-<b><i>Ascaris</i></b> IgE as a Risk Factor for Asthma Symptoms among 5-Year-Old Children in Rural Bangladesh with Even Decreased <b><i>Ascaris</i></b> Infection Prevalence by Takeuchi H. (12022622)

“…The association of anti-<i>Ascaris</i> IgE with increased asthma symptoms among children from a general population with a mild to moderate <i>Ascaris</i> infection prevalence was investigated. …”

Activity-dependent decrease in synaptic clusters of GABA_AR preceding that of gephyrin. by Fumihiro Niwa (168651)

“…<p>Left: Representative examples of immunoreactivity associated with GABA_AR (<b>A</b>, <b>C</b>) and gephyrin (<b>B</b>, <b>D</b>, <b>E</b>) in the presence (<b>A</b>, <b>B</b>: 4AP, <b>C</b>–<b>E</b>: NMDA) or absence (Con) of stimulation for the indicated times. …”

Growth disadvantage conferred by RecA D112R. by Irina V. Bakhlanova (2636080)

EL4 tumor growth causes a decrease in splenic and bone marrow NK cells. by John Richards (53768)

Establishing environmental soil phosphorus thresholds to decrease the risk of losses to water in soils from Rio Grande do Sul, Brazil by Luciano Colpo Gatiboni (4619761)

Stabilization of Hif-1α at early stages of infection leads to a decrease in bacterial burden. by Philip M. Elks (324793)

“…<p>(A) Quantification of bacterial burden by fluorescent pixel count after DMOG treatment between 5 and 6 dpi. …”

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. by Dennis Ochola (11626912)

Decreasing leads to smaller number of spikes but does not change the resting membrane potential. by Carlos Perez (1299798)

DataSheet1_A Non-Synonymous Point Mutation in a WD-40 Domain Repeat of EML5 Leads to Decreased Bovine Sperm Quality and Fertility.docx by Eriklis Nogueira (7475576)